Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions.
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DNA Sequence Modulates the Conformation of the Food Mutagen 2-Amino-3-methylimidazo[4,5- f ]quinoline in the Recognition Sequence of the Nar I Restriction Enzyme † , ‡Base-displaced intercalation of the 2-amino-3-methylimidazo[4,5-f]quinolone N2-dG adduct in the NarI DNA recognition sequenceMetabolism and biomarkers of heterocyclic aromatic amines in molecular epidemiology studies: lessons learned from aromatic aminesBase-Displaced Intercalated Structure of the N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone DNA Adduct.Conformational differences of the C8-deoxyguanosine adduct of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) within the NarI recognition sequence.The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro.Structural and energetic characterization of the major DNA adduct formed from the food mutagen ochratoxin A in the NarI hotspot sequence: influence of adduct ionization on the conformational preferences and implications for the NER propensityStructure-based DNA-targeting strategies with small molecule ligands for drug discovery.Bifacial nucleoside as a surrogate for both T and A in duplex DNA.Synthesis of oligonucleotides containing the N2-deoxyguanosine adduct of the dietary carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline.Translesion synthesis past the C8- and N2-deoxyguanosine adducts of the dietary mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in the NarI recognition sequence by prokaryotic DNA polymerasesBase-Displaced Intercalated Conformation of the 2-Amino-3-methylimidazo[4,5-f]quinoline N(2)-dG DNA Adduct Positioned at the Nonreiterated G(1) in the NarI Restriction Site.Conformational and thermodynamic properties modulate the nucleotide excision repair of 2-aminofluorene and 2-acetylaminofluorene dG adducts in the NarI sequence.DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cellsChemical and electrochemical oxidation of C8-arylamine adducts of 2'-deoxyguanosineDNA adduct structure-function relationships: comparing solution with polymerase structures.Influence of flanking sequence context on the conformational flexibility of aminofluorene-modified dG adduct in dA mismatch DNA duplexes.Synthesis of oxygen-linked 8-phenoxyl-deoxyguanosine nucleoside analogues.DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.Chemistry and structural biology of DNA damage and biological consequencesC8-linked bulky guanosine DNA adducts: experimental and computational insights into adduct conformational preferences and resulting mutagenicity.Double-stranded RNA-binding artificial cationic oligosaccharides stabilizing siRNAs with a low N/P ratio.Adenine versus guanine DNA adducts of aristolochic acids: role of the carcinogen-purine linkage in the differential global genomic repair propensity.Translesion Synthesis of the N(2)-2'-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases η, ζ, and Rev1.Repair-Resistant DNA Lesions.Conformational insights into the lesion and sequence effects for arylamine-induced translesion DNA synthesis: 19F NMR, surface plasmon resonance, and primer kinetic studies.Enthalpy-entropy contribution to carcinogen-induced DNA conformational heterogeneityStructural and biochemical impact of C8-aryl-guanine adducts within the NarI recognition DNA sequence: influence of aryl ring size on targeted and semi-targeted mutagenicityProbing the sequence effects on NarI-induced -2 frameshift mutagenesis by dynamic 19F NMR, UV, and CD spectroscopy.Translesion Synthesis of 2'-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases.AMOEBA Polarizable Atomic Multipole Force Field for Nucleic Acids.Synergistic effects of H3 and H4 nucleosome tails on structure and dynamics of a lesion-containing DNA: Binding of a displaced lesion partner base to the H3 tail for GG-NER recognition.
P2860
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P2860
Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions.
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2006 nî lūn-bûn
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2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2006 թվականի օգոստոսին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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name
Base-displaced intercalated st ...... a hotspot for -2 bp deletions.
@ast
Base-displaced intercalated st ...... a hotspot for -2 bp deletions.
@en
type
label
Base-displaced intercalated st ...... a hotspot for -2 bp deletions.
@ast
Base-displaced intercalated st ...... a hotspot for -2 bp deletions.
@en
prefLabel
Base-displaced intercalated st ...... a hotspot for -2 bp deletions.
@ast
Base-displaced intercalated st ...... a hotspot for -2 bp deletions.
@en
P2093
P2860
P356
P1476
Base-displaced intercalated st ...... a hotspot for -2 bp deletions.
@en
P2093
C Eric Elmquist
James S Stover
Michael P Stone
Nicholas E DeMuro
P2860
P304
10085-10095
P356
10.1021/JA062004V
P407
P577
2006-08-01T00:00:00Z