Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression - Wikidata - awgldk - TriplyDB

Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression

Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression

http://www.wikidata.org/entity/Q28610062

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Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer Deregulated signaling pathways in glioblastoma multiforme: molecular mechanisms and therapeutic targets The Ca(2+) -activated Cl(-) channel, ANO1 (TMEM16A), is a double-edged sword in cell proliferation and tumorigenesis Circulating tumor cells in the diagnosis and management of pancreatic cancer The New Role for an Old Kinase: Protein Kinase CK2 Regulates Metal Ion Transport Decreased zinc in the development and progression of malignancy: an important common relationship and potential for prevention and treatment of carcinomas.Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function.A tumorigenic factor interactome connected through tumor suppressor microRNA-198 in human pancreatic cancer.ZIP4 confers resistance to zinc deficiency-induced apoptosis in pancreatic cancer.Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration.ZIP4 regulates pancreatic cancer cell growth by activating IL-6/STAT3 pathway through zinc finger transcription factor CREB.ZIP4 upregulates the expression of neuropilin-1, vascular endothelial growth factor, and matrix metalloproteases in pancreatic cancer cell lines and xenografts Free zinc ions outside a narrow concentration range are toxic to a variety of cells in vitro Maternal folate supply and sex influence gene-specific DNA methylation in the fetal gut.Thymosin beta-10 is aberrantly expressed in pancreatic cancer and induces JNK activation Somatostatin receptor-1 induces cell cycle arrest and inhibits tumor growth in pancreatic cancer.Profiling of 95 microRNAs in pancreatic cancer cell lines and surgical specimens by real-time PCR analysis Molecular pathogenesis of spondylocheirodysplastic Ehlers-Danlos syndrome caused by mutant ZIP13 proteins.Uptake epithelia behave in a cell-centric and not systems homeostatic manner in response to zinc depletion and supplementation.Zinc in innate and adaptive tumor immunity.Zinc in specialized secretory tissues: roles in the pancreas, prostate, and mammary gland.Clioquinol synergistically augments rescue by zinc supplementation in a mouse model of acrodermatitis enteropathica Overcoming drug resistance in pancreatic cancer.Zinc transporter expression in zebrafish (Danio rerio) during development.Genomic profiling guides the choice of molecular targeted therapy of pancreatic cancer.The large intracellular loop of hZIP4 is an intrinsically disordered zinc binding domain Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration.Zinc and cancer: implications for LIV-1 in breast cancer.Imaging-guided curative surgical resection of pancreatic cancer in a xenograft mouse model.Pathological fractures in predicting clinical outcomes for patients with osteosarcoma.Cellular sensing and transport of metal ions: implications in micronutrient homeostasis.Cellular mechanisms of zinc dysregulation: a perspective on zinc homeostasis as an etiological factor in the development and progression of breast cancer.ZIP4 silencing improves bone loss in pancreatic cancer In Vivo Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors.Study human pancreatic cancer in mice: how close are they?The genetics of essential metal homeostasis during development New applications of old metal-binding drugs in the treatment of human cancer.Dithiocarbamate-based coordination compounds as potent proteasome inhibitors in human cancer cells.ZIP4 is a novel molecular marker for glioma.Structural insights of ZIP4 extracellular domain critical for optimal zinc transport

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Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression

http://www.wikidata.org/entity/Q28610062

description

2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

article publié dans les Procee ...... f the United States of America

@fr

artículu científicu espublizáu en 2007

@ast

im November 2007 veröffentlichter wissenschaftlicher Artikel

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scientific journal article

@en

vedecký článok (publikovaný 2007/11/20)

@sk

vědecký článek publikovaný v roce 2007

@cs

wetenschappelijk artikel (gepubliceerd op 2007/11/20)

@nl

наукова стаття, опублікована в листопаді 2007

@uk

name

Aberrant expression of zinc tr ...... r pathogenesis and progression

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Aberrant expression of zinc tr ...... r pathogenesis and progression

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Aberrant expression of zinc tr ...... r pathogenesis and progression

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type

label

Aberrant expression of zinc tr ...... r pathogenesis and progression

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Aberrant expression of zinc tr ...... r pathogenesis and progression

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Aberrant expression of zinc tr ...... r pathogenesis and progression

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prefLabel

Aberrant expression of zinc tr ...... r pathogenesis and progression

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Aberrant expression of zinc tr ...... r pathogenesis and progression

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Aberrant expression of zinc tr ...... r pathogenesis and progression

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PNAS.0709307104

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Proceedings of the National Academy of Sciences of the United States of America

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Aberrant expression of zinc tr ...... r pathogenesis and progression

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Changyi Chen

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Craig D. Logsdon

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F. Charles Brunicardi

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Hao Wang

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Juan P. Liuzzi

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Min Li

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Qizhi Yao

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Robert J. Cousins

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Sheng Zhang

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Shou-Mei Chang

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P2860

The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots

cDNA array analysis identifies thymic LCK as upregulated in moderate murine zinc deficiency before T-lymphocyte population changes

Zn2+-stimulated endocytosis of the mZIP4 zinc transporter regulates its location at the plasma membrane

Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters

The SLC39 family of metal ion transporters

Identification of SLC39A4, a gene involved in acrodermatitis enteropathica

The ZIP family of metal transporters.

Mammalian zinc transport, trafficking, and signals.

Cancer statistics, 1998.

A novel member of a zinc transporter family is defective in acrodermatitis enteropathica.

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18636–18641

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10.1073/PNAS.0709307104

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