A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS) - Wikidata - awgldk - TriplyDB

A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS)

A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS)

http://www.wikidata.org/entity/Q28610409

about

T cell activation Roquin--a multifunctional regulator of immune homeostasis ICOS Co-Stimulation: Friend or Foe?Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling CD28 and CTLA-4 coreceptor expression and signal transduction Controlling NF-kappaB activation in T cells by costimulatory receptors CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis Evidence implicating the Ras pathway in multiple CD28 costimulatory functions in CD4+ T cells AP-1 is involved in ICOS gene expression downstream of TCR/CD28 and cytokine receptor signaling Quantitative analysis by surface plasmon resonance of CD28 interaction with cytoplasmic adaptor molecules Grb2, Gads and p85 PI3K.Antigen-independent adhesion and cell spreading by inducible costimulator engagement inhibits T cell migration in a PI-3K-dependent manner.Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation.Chimeric antigen receptors for T cell immunotherapy: current understanding and future directions The B7/CD28 costimulatory family in autoimmunity.The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.Molecules involved in T-B co-stimulation and B cell homeostasis: possible targets for an immunological intervention in autoimmunity.Genetic defects in common variable immunodeficiency PD-1 signaling in primary T cells Dynamic regulation of T cell activation and co-stimulation through TCR-microclusters.CD28 co-signaling in the adaptive immune response.Biased binding of class IA phosphatidyl inositol 3-kinase subunits to inducible costimulator (CD278).Akt is a neutral amplifier for Th cell differentiation.Multifaceted role of BTLA in the control of CD8+ T cell fate after antigen encounter.Signals that drive T follicular helper cell formation.The regulation of T-cell cytokine production by ICOS-B7H2 interactions at the human fetomaternal interface.Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse.CD28 and Grb-2, relative to Gads or Grap, preferentially co-operate with Vav1 in the activation of NFAT/AP-1 transcription.ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6 Membrane Rafts in T Cell Activation: A Spotlight on CD28 Costimulation.Glycogen Synthase Kinase 3 Inactivation Compensates for the Lack of CD28 in the Priming of CD8+ Cytotoxic T-Cells: Implications for anti-PD-1 Immunotherapy.PI3K binds ICOS Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins.CD28 signaling in primary CD4(+) T cells: identification of both tyrosine phosphorylation-dependent and phosphorylation-independent pathways.Coming of Age: CD96 Emerges as Modulator of Immune Responses.ICOS signal facilitates Foxp3 transcription to favor suppressive function of regulatory T cells.

P2860

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P2860

A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS)

http://www.wikidata.org/entity/Q28610409

description

2003 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հունվարին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2003

@ast

im Januar 2003 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2003/01/20)

@sk

vědecký článek publikovaný v roce 2003

@cs

wetenschappelijk artikel (gepubliceerd op 2003/01/20)

@nl

наукова стаття, опублікована в січні 2003

@uk

مقالة علمية (نشرت في 20-1-2003)

@ar

name

A single amino acid alteration ...... inducible costimulator (ICOS)

@ast

A single amino acid alteration ...... inducible costimulator (ICOS)

@en

A single amino acid alteration ...... inducible costimulator (ICOS)

@nl

type

label

A single amino acid alteration ...... inducible costimulator (ICOS)

@ast

A single amino acid alteration ...... inducible costimulator (ICOS)

@en

A single amino acid alteration ...... inducible costimulator (ICOS)

@nl

prefLabel

A single amino acid alteration ...... inducible costimulator (ICOS)

@ast

A single amino acid alteration ...... inducible costimulator (ICOS)

@en

A single amino acid alteration ...... inducible costimulator (ICOS)

@nl

P1433

Q28610409-33908097-3AE0-4759-89F8-062D1FCFED9B

P1476

Q28610409-86AEFFB2-22C5-4278-B7E1-390E0239A1CA

P2093

Q28610409-144D805D-6AD0-4C68-A6B2-5ED70F26D58B

Q28610409-4D5062CB-1756-4B12-A37C-A935FF343D12

Q28610409-7459499E-E4F5-467E-BEC5-F10BC1473BED

Q28610409-7B2E3569-EC61-4B1C-A9F9-899F5FC62738

Q28610409-89C7D1A9-DCFF-4C5A-A33D-D934FDB16C1C

Q28610409-B704BA6B-3716-4DE0-B45D-45BB5ADCE371

Q28610409-BE8FC8E3-7D22-4A62-BAF3-BBE2D50E80D4

Q28610409-CE97D99F-C39A-467F-B101-1EA64EF1CE2A

Q28610409-E76103D3-B313-44AD-87DE-F753D051DF03

P2860

Q28610409-094E9139-FFC3-49DE-B6EC-7DB7757B99D2

Q28610409-2075D1DD-DB94-476F-9FDE-D56A0DA99AD0

Q28610409-2664D217-CB79-4531-AC65-C5B66992B33B

Q28610409-2834A119-2D17-497B-A018-B87ECA302EFF

Q28610409-298D9785-04B3-4C3B-83F4-DCDFE7CDF34F

Q28610409-31705B5A-BC3D-4929-9361-656FB97842B0

Q28610409-406A6437-3223-4E52-B836-B83EF9902514

Q28610409-4CDA90B4-9FA7-4E77-B7C3-32D636682A4E

Q28610409-4EE77FD7-25D4-4B67-B288-6D417AE6F34A

Q28610409-50058694-3D9E-41E2-9FE1-F92D5D95B98C

P304

Q28610409-2A61B595-3123-4760-9C38-A9C689EEA757

P31

Q28610409-29808EC0-0F17-4753-8690-B9A55472C2D2

P3181

Q28610409-EF271219-955C-40DC-B576-9BCED45EA454

P356

Q28610409-8D646D88-E4B4-4E13-A24E-11EFC4F0108C

P407

Q28610409-FC7A90C7-761A-46A9-9F69-D2C54F0F3523

P433

Q28610409-08A9EC8A-7033-4E1D-826F-A35777C827EB

P478

Q28610409-0CDF3C79-1264-4192-A34D-39891354508C

P577

Q28610409-E29F6C02-F11A-4D07-8D0E-E7AABFF68B67

P5875

Q28610409-5DFA4D1F-907A-4E89-A18B-E21FD4CAE6C6

P698

Q28610409-1BDF80C5-691B-4787-B19D-118D2A46FB46

P932

Q28610409-8151FC99-1EE4-4507-A78C-B6CB0C6F4C58

P3181

P356

P1433

Journal of Experimental Medicine

P1476

A single amino acid alteration ...... inducible costimulator (ICOS)

@en

P2093

Amnon Altman

http://www.w3.org/2001/XMLSchema#string

Daisuke Ohgai

http://www.w3.org/2001/XMLSchema#string

Hiroshi Toma

http://www.w3.org/2001/XMLSchema#string

Kazuhiro Okano

http://www.w3.org/2001/XMLSchema#string

Kazunari Tanabe

http://www.w3.org/2001/XMLSchema#string

Osamu Koiwai

http://www.w3.org/2001/XMLSchema#string

Ryo Abe

http://www.w3.org/2001/XMLSchema#string

Ryosuke Watanabe

http://www.w3.org/2001/XMLSchema#string

Yohsuke Harada

http://www.w3.org/2001/XMLSchema#string

P2860

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

T-cell co-stimulation through B7RP-1 and ICOS

ICOS co-stimulatory receptor is essential for T-cell activation and function

AILIM/ICOS: a novel lymphocyte adhesion molecule

ICOS is critical for CD40-mediated antibody class switching

ICOS is essential for effective T-helper-cell responses

Cellular survival: a play in three Akts

Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation

Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo.

The B7-CD28 superfamily.

P304

257–262

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

4160341

http://www.w3.org/2001/XMLSchema#string

P356

10.1084/JEM.20021305

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

197

http://www.w3.org/2001/XMLSchema#string

P577

2003-01-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

10940550

http://www.w3.org/2001/XMLSchema#string

P698

12538664

http://www.w3.org/2001/XMLSchema#string

P932

2193818

http://www.w3.org/2001/XMLSchema#string