ICOS co-stimulatory receptor is essential for T-cell activation and function
about
B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cellsICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cellsAntigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivityNo evidence for dualism in function and receptors: PD-L2/B7-DC is an inhibitory regulator of human T cell activationFollicular helper T cells: lineage and locationThe costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cellsLigand binding sites of inducible costimulator and high avidity mutants with improved functionCurrent status of immunotherapyAutoimmune therapies targeting costimulation and emerging trends in multivalent therapeuticsThe role of costimulatory receptors of the tumour necrosis factor receptor family in atherosclerosisImmunoregulatory molecules are master regulators of inflammation during the immune responseTregs Modulate Lymphocyte Proliferation, Activation, and Resident-Memory T-Cell Accumulation within the Brain during MCMV InfectionICOS Co-Stimulation: Friend or Foe?The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signallingIn situ expression and significance of B7 costimulatory molecules within tissues of human gastric carcinomaUnifying concepts in CD28, ICOS and CTLA4 co-receptor signallingExpression of the costimulatory molecule B7-H2 (inducible costimulator ligand) by human airway epithelial cellsGenetics of type 1 diabetes mellitusCo-stimulatory pathways in lymphocyte regulation: the immunoglobulin superfamilyVISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responsesT helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gammaA RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunityGeneration and characterization of B7-H4/B7S1/B7x-deficient miceBTNL2, a butyrophilin-like molecule that functions to inhibit T cell activationThe B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responsesA single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS)Cloning and characterization of porcine 4Ig-B7-H3: a potent inhibitor of porcine T-cell activationA distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17Modulation of NKT cell development by B7-CD28 interaction: an expanding horizon for costimulation.Separable effector T cell populations specialized for B cell help or tissue inflammation.T cell immune abnormalities in immune thrombocytopenia.Inducible costimulator expression regulates the magnitude of Th2-mediated airway inflammation by regulating the number of Th2 cellsCorrelation of clinical and immunological data in a metastatic melanoma patient with heterogeneous tumor responses to ipilimumab therapyRegulation of T cell response by blocking the ICOS signal with the B7RP-1-specific small antibody fragment isolated from human antibody phage library.ICOS promotes IL-17 synthesis in colonic intraepithelial lymphocytes in IL-10-/- mice.Production of IgG antibodies to pneumococcal polysaccharides is associated with expansion of ICOS+ circulating memory T follicular-helper cells which is impaired by HIV infection.Innate and adaptive immunity in atherosclerosis.The inducible T-cell co-stimulator molecule is expressed on subsets of T cells and is a new marker of lymphomas of T follicular helper cell-derivation.ICOS/ICOSL interaction is required for CD4+ invariant NKT cell function and homeostatic survival.B7h is required for T cell activation, differentiation, and effector function.
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P2860
ICOS co-stimulatory receptor is essential for T-cell activation and function
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
ICOS co-stimulatory receptor is essential for T-cell activation and function
@ast
ICOS co-stimulatory receptor is essential for T-cell activation and function
@en
ICOS co-stimulatory receptor is essential for T-cell activation and function
@nl
type
label
ICOS co-stimulatory receptor is essential for T-cell activation and function
@ast
ICOS co-stimulatory receptor is essential for T-cell activation and function
@en
ICOS co-stimulatory receptor is essential for T-cell activation and function
@nl
prefLabel
ICOS co-stimulatory receptor is essential for T-cell activation and function
@ast
ICOS co-stimulatory receptor is essential for T-cell activation and function
@en
ICOS co-stimulatory receptor is essential for T-cell activation and function
@nl
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ICOS co-stimulatory receptor is essential for T-cell activation and function
@en
P2093
A E Juedes
J P Allison
N H Ruddle
R A Flavell
U A Temann
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P2888
P304
P3181
P356
10.1038/35051100
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P577
2001-01-04T00:00:00Z
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P6179
1029587160