Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73
about
Oncogenic Intra-p53 Family Member Interactions in Human CancersThe Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome SystemRecurrent epimutations activate gene body promoters in primary glioblastomap73 as a pharmaceutical target for cancer therapyFunctional interplay between MDM2, p63/p73 and mutant p53TP53 NetworkdeltaNp73 facilitates cell immortalization and cooperates with oncogenic Ras in cellular transformation in vivoOverexpressed TP73 induces apoptosis in medulloblastomaThe antiapoptotic DeltaNp73 is degraded in a c-Jun-dependent manner upon genotoxic stress through the antizyme-mediated pathway.BUB3 that dissociates from BUB1 activates caspase-independent mitotic death (CIMD).Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2.TAp73 and ΔNp73 have opposing roles in 5-aza-2'-deoxycytidine-induced apoptosis in breast cancer cells.Regulation of p53 family member isoform DeltaNp63alpha by the nuclear factor-kappaB targeting kinase IkappaB kinase betaTranscriptional regulation of the p73 gene by Nrf-2 and promoter CpG methylation in human breast cancer.Regulation of ΔNp63α by NFκΒU-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of DeltaNp63alpha.Ubiquitin and ubiquitin-like modifications of the p53 family.p73 in Cancer.Hsp72 mediates TAp73α anti-apoptotic effects in small cell lung carcinoma cells.p53 Family: Role of Protein Isoforms in Human Cancer.Aberrant expression of DeltaNp73 in benign and malignant tumours of the prostate: correlation with Gleason scoreAssociation of p73 G4C14-to-A4T14 polymorphism with non-small cell lung cancer risk.Interplay between TAp73 Protein and Selected Activator Protein-1 (AP-1) Family Members Promotes AP-1 Target Gene Activation and Cellular Growth.DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors.Specific isoforms of p73 control the induction of cell death induced by the viral proteins, E1A or apoptinHigh ΔNp73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia.Therapeutic prospects for p73 and p63: rising from the shadow of p53.Regulatory feedback loop between TP73 and TRIM32.The interaction between C35 and ΔNp73 promotes chemo-resistance in ovarian cancer cellsHow many mutant p53 molecules are needed to inactivate a tetramer?ΔNp73 overexpression promotes resistance to apoptosis but does not cooperate with PML/RARA in the induction of an APL-leukemic phenotype.Senescence regulation by the p53 protein familyThe Role of the Transmembrane RING Finger Proteins in Cellular and Organelle Functionp73-Binding Partners and Their Functional Significance.p53- and p73-independent activation of TIGAR expression in vivo.IkappaB kinase beta promotes cell survival by antagonizing p53 functions through DeltaNp73alpha phosphorylation and stabilization.DeltaNp73beta is active in transactivation and growth suppression.p73 is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF and TGFβ signaling.p73 plays a role in erythroid differentiation through GATA1 induction.p73 deficiency results in impaired self renewal and premature neuronal differentiation of mouse neural progenitors independently of p53.
P2860
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P2860
Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73
description
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Februar 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/02/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/02/01)
@nl
наукова стаття, опублікована в лютому 2002
@uk
مقالة علمية (نشرت في فبراير 2002)
@ar
name
Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73
@ast
Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73
@en
Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73
@nl
type
label
Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73
@ast
Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73
@en
Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73
@nl
prefLabel
Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73
@ast
Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73
@en
Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73
@nl
P2093
P3181
P1433
P1476
Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73
@en
P2093
Chikashi Kawahara
Kentaro Enjo
Masuo Obinata
Osamu Ishimoto
Shuntaro Ikawa
Toshihiro Nukiwa
P304
P3181
P407
P577
2002-02-01T00:00:00Z