Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. - Wikidata - awgldk - TriplyDB

Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2.

Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2.

http://www.wikidata.org/entity/Q34059266

about

Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosis RBR E3 ubiquitin ligases: new structures, new insights, new questions Structure and apoptotic function of p73 Structure and Kinetic Stability of the p63 Tetramerization Domain RNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damage The p53 circuit board p73 as a pharmaceutical target for cancer therapy TP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy.p63 transcriptionally regulates the expression of matrix metallopeptidase 13.Transcriptional regulation of the p73 gene by Nrf-2 and promoter CpG methylation in human breast cancer.p53 Family and Cellular Stress Responses in Cancer.p73 in Cancer.Induction of apoptotic genes by a p73-phosphatase and tensin homolog (p73-PTEN) protein complex in response to genotoxic stress.Regulation of p73 activity by post-translational modifications.TAp73 transcriptionally represses BNIP3 expression.Regulation of RNF144A E3 Ubiquitin Ligase Activity by Self-association through Its Transmembrane Domain Disruption of chromosomal locus 1p36 differentially modulates TAp73 and ΔNp73 expression in follicular lymphoma.High ΔNp73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia.TAp73 protein stability is controlled by histone deacetylase 1 via regulation of Hsp90 chaperone function.Analysis of the oligomeric state and transactivation potential of TAp73α.Regulatory feedback loop between TP73 and TRIM32.p53 and p73 Regulate Apoptosis but Not Cell-Cycle Progression in Mouse Embryonic Stem Cells upon DNA Damage and Differentiation.Functions, divergence and clinical value of TAp73 isoforms in cancer.The TP73 complex network: ready for clinical translation in cancer?How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors.The Role of the Transmembrane RING Finger Proteins in Cellular and Organelle Function Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities.Emerging from the shade of p53 mutants: N-terminally truncated variants of the p53 family in EMT signaling and cancer progression.A balancing act: orchestrating amino-truncated and full-length p73 variants as decisive factors in cancer progression.p73-Binding Partners and Their Functional Significance.High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy DEC1 coordinates with HDAC8 to differentially regulate TAp73 and ΔNp73 expression.p73 regulates serine biosynthesis in cancer.PIR2/Rnf144B regulates epithelial homeostasis by mediating degradation of p21WAF1 and p63.Apoptin induces apoptosis by changing the equilibrium between the stability of TAp73 and ΔNp73 isoforms through ubiquitin ligase PIR2.The E3 ubiquitin ligase RNF144B is LPS-inducible in human, but not mouse, macrophages and promotes inducible IL-1β expression.Rapamycin regulates biochemical metabolites.Relative expression of TAp73 and ΔNp73 isoforms.WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ΔNp73 levels.Pir2/Rnf144b is a potential endometrial cancer biomarker that promotes cell proliferation.

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P2860

Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2.

http://www.wikidata.org/entity/Q34059266

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Differential control of TAp73 ...... finger ubiquitin ligase PIR2.

@ast

Differential control of TAp73 ...... finger ubiquitin ligase PIR2.

@en

Differential control of TAp73 ...... finger ubiquitin ligase PIR2.

@nl

type

label

Differential control of TAp73 ...... finger ubiquitin ligase PIR2.

@ast

Differential control of TAp73 ...... finger ubiquitin ligase PIR2.

@en

Differential control of TAp73 ...... finger ubiquitin ligase PIR2.

@nl

prefLabel

Differential control of TAp73 ...... finger ubiquitin ligase PIR2.

@ast

Differential control of TAp73 ...... finger ubiquitin ligase PIR2.

@en

Differential control of TAp73 ...... finger ubiquitin ligase PIR2.

@nl

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PNAS.0911828107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Differential control of TAp73 ...... g finger ubiquitin ligase PIR2

@en

P2093

Ai Li Yang

http://www.w3.org/2001/XMLSchema#string

Berna S Sayan

http://www.w3.org/2001/XMLSchema#string

Franco Conforti

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Gareth J Browne

http://www.w3.org/2001/XMLSchema#string

Gerry Melino

http://www.w3.org/2001/XMLSchema#string

Maria Cristina Piro

http://www.w3.org/2001/XMLSchema#string

Paola Tucci

http://www.w3.org/2001/XMLSchema#string

Richard A Knight

http://www.w3.org/2001/XMLSchema#string

Sergio Bernardini

http://www.w3.org/2001/XMLSchema#string

Tak W Mak

http://www.w3.org/2001/XMLSchema#string

P2860

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

The ubiquitin-protein ligase Itch regulates p73 stability

The p53-inducible E3 ubiquitin ligase p53RFP induces p53-dependent apoptosis

p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1

The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73

The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch

The ubiquitin system

A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73

An anti-apoptotic role for the p53 family member, p73, during developmental neuron death

Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73

P304

12877-12882

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scholarly article

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10.1073/PNAS.0911828107

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P407

P433

29

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P478

107

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Massimiliano Agostini

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2010-07-06T00:00:00Z

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45113508

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20615966

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2919933

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