Selective killing of human malignant cell lines deficient in methylthioadenosine phosphorylase, a purine metabolic enzyme
about
Assignment of the gene for methylthioadenosine phosphorylase to human chromosome 9 by mouse-human somatic cell hybridizationGenomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancersDiscovery of a potent, nonpolyglutamatable inhibitor of glycinamide ribonucleotide transformylaseHomozygous deletion of the alpha- and beta 1-interferon genes in human leukemia and derived cell linesSelective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy.Continuous Fluorescence Assays for Reactions Involving AdenineChemical genetic screening for compounds that preferentially inhibit growth of methylthioadenosine phosphorylase (MTAP)-deficient Saccharomyces cerevisiaeEFA (9-beta-D-erythrofuranosyladenine) is an effective salvage agent for methylthioadenosine phosphorylase-selective therapy of T-cell acute lymphoblastic leukemia with L-alanosine.Characterization of MTAP Gene Expression in Breast Cancer Patients and Cell LinesComprehensive analysis of the 9p21 region in neuroblastoma suggests a role for genes mapping to 9p21-23 in the biology of favourable stage 4 tumoursAssociation of common variants in MTAP with susceptibility and overall survival of osteosarcoma: a two-stage population-based study in Han Chinese.Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategiesRecent advances in the biochemistry of polyamines in eukaryotes.Six-layer structure for genomics and its applications.Deletion of dinucleotide repeat (Delta 14 allele) in the methylthioadenosine phosphorylase (MTAP) promoter and the allelotype of MTAP promoter in the Japanese population.Methional derived from 4-methylthio-2-oxobutanoate is a cellular mediator of apoptosis in BAF3 lymphoid cells.Primate genome gain and loss: a bone dysplasia, muscular dystrophy, and bone cancer syndrome resulting from mutated retroviral-derived MTAP transcripts.Regulation of human methylthioadenosine phosphorylase gene by the CBF (CCAAT binding factor)/NF-Y (nuclear factor-Y)Deficiency of 5'-deoxy-5'-methylthioadenosine phosphorylase activity in malignancy. Absence of the protein in human enzyme-deficient cell linesThe methylthioadenosine phosphorylase gene is frequently co-deleted with the p16INK4a gene in acute type adult T-cell leukemia.MTA is cleaved and phosphorylatedMitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation.4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents
P2860
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P2860
Selective killing of human malignant cell lines deficient in methylthioadenosine phosphorylase, a purine metabolic enzyme
description
1981 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1981 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1981
@ast
im Februar 1981 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1981/02/01)
@sk
vědecký článek publikovaný v roce 1981
@cs
wetenschappelijk artikel (gepubliceerd op 1981/02/01)
@nl
наукова стаття, опублікована в лютому 1981
@uk
name
Selective killing of human mal ...... ase, a purine metabolic enzyme
@ast
Selective killing of human mal ...... ase, a purine metabolic enzyme
@en
Selective killing of human mal ...... ase, a purine metabolic enzyme
@nl
type
label
Selective killing of human mal ...... ase, a purine metabolic enzyme
@ast
Selective killing of human mal ...... ase, a purine metabolic enzyme
@en
Selective killing of human mal ...... ase, a purine metabolic enzyme
@nl
prefLabel
Selective killing of human mal ...... ase, a purine metabolic enzyme
@ast
Selective killing of human mal ...... ase, a purine metabolic enzyme
@en
Selective killing of human mal ...... ase, a purine metabolic enzyme
@nl
P2093
P2860
P356
P1476
Selective killing of human mal ...... ase, a purine metabolic enzyme
@en
P2093
D. A. Carson
N. Kamatani
W. A. Nelson-Rees
P2860
P304
P356
10.1073/PNAS.78.2.1219
P407
P577
1981-02-01T00:00:00Z