Negative regulation by HLA-DO of MHC class II-restricted antigen processing - Wikidata - awgldk - TriplyDB

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

http://www.wikidata.org/entity/Q28613199

about

Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis Human leukocyte Antigen-DM polymorphisms in autoimmune diseases HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice Proteases involved in MHC class II antigen presentation The impact of the non-classical MHC proteins HLA-DM and HLA-DO on loading of MHC class II molecules Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction Cytomegalovirus infection enhances the immune response to influenza.The binding of TAPBPR and Tapasin to MHC class I is mutually exclusive.Upregulation of the CLIP self peptide on mature dendritic cells antagonizes T helper type 1 polarization.Pathways of antigen processing.Phagocytic antigen processing and effects of microbial products on antigen processing and T-cell responses.Targeted regulation of self-peptide presentation prevents type I diabetes in mice without disrupting general immunocompetence.A point mutation in the groove of HLA-DO allows egress from the endoplasmic reticulum independent of HLA-DM.Intracellular transport and peptide loading of MHC class II molecules: regulation by chaperones and motors.Peptide exchange in MHC molecules.The role of H2-O and HLA-DO in major histocompatibility complex class II-restricted antigen processing and presentation.Inflammation-related genetic variations and survival in patients with advanced non-small cell lung cancer receiving first-line chemotherapy On the perils of poor editing: regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes.H2-O, a MHC class II-like protein, sets a threshold for B-cell entry into germinal centers.Phagocytic processing of antigens for presentation by class II major histocompatibility complex molecules.Genetic variants in major histocompatibility complex-linked genes associate with pediatric liver transplant rejection.Binding interactions between peptides and proteins of the class II major histocompatibility complex.Early endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM.Functional HLA-DM on the surface of B cells and immature dendritic cells.HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation.Clustering of MHC-peptide complexes prior to their engagement in the immunological synapse: lipid raft and tetraspan microdomains.The mechanism of HLA-DM induced peptide exchange in the MHC class II antigen presentation pathway Compartmentalization of class II antigen presentation: contribution of cytoplasmic and endosomal processing.Right place, right time, right peptide: DO keeps DM focused.pH-susceptibility of HLA-DO tunes DO/DM ratios to regulate HLA-DM catalytic activity.Invariant chain controls H2-M proteolysis in mouse splenocytes and dendritic cells DM determines the cryptic and immunodominant fate of T cell epitopes.Regulated expression of human histocompatibility leukocyte antigen (HLA)-DO during antigen-dependent and antigen-independent phases of B cell development.Conformational variants of class II MHC/peptide complexes induced by N- and C-terminal extensions of minimal peptide epitopes.Ubiquitination of HLA-DO by MARCH family E3 ligases.GILT expression in B cells diminishes cathepsin S steady-state protein expression and activity.MHC class II molecules on the move for successful antigen presentation.MHC class II antigen presentation and immunological abnormalities due to deficiency of MHC class II and its associated genes.MHC class II transport at a glance

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Negative regulation by HLA-DO of MHC class II-restricted antigen processing

http://www.wikidata.org/entity/Q28613199

description

1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Science

@fr

artículu científicu espublizáu en 1997

@ast

im Oktober 1997 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1997/10/03)

@sk

vědecký článek publikovaný v roce 1997

@cs

wetenschappelijk artikel (gepubliceerd op 1997/10/03)

@nl

наукова стаття, опублікована в жовтні 1997

@uk

name

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

@ast

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

@en

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

@nl

type

label

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

@ast

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

@en

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

@nl

prefLabel

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

@ast

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

@en

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

@nl

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P356

SCIENCE.278.5335.106

P1433

P1476

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

@en

P2093

C. Hammond

http://www.w3.org/2001/XMLSchema#string

D. B. Sant'Angelo

http://www.w3.org/2001/XMLSchema#string

L. K. Denzin

http://www.w3.org/2001/XMLSchema#string

M. J. Surman

http://www.w3.org/2001/XMLSchema#string

P. Cresswell

http://www.w3.org/2001/XMLSchema#string

P2860

HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading

DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide

HLA-DO is an intracellular class II molecule with distinctive thymic expression

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH

Assembly, transport, and function of MHC class II molecules.

Isolation and characterization of the intracellular MHC class II compartment.

T cell-dependent B cell activation.

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106–109

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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4370828

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10.1126/SCIENCE.278.5335.106

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5335

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278

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9311912

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