Cytoplasmic retention, DNA binding and processing of the NF-kappa B p50 precursor are controlled by a small region in its C-terminus
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I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA bindingPurification of the major histocompatibility complex class I transcription factor H2TF1. The full-length product of the nfkb2 geneBCL3 encodes a nuclear protein which can alter the subcellular location of NF-kappa B proteinsNuclear uptake control of NF-kappa B by MAD-3, an I kappa B protein present in the nucleusRegulation of NFKB1 proteins by the candidate oncoprotein BCL-3: generation of NF-kappaB homodimers from the cytoplasmic pool of p50-p105 and nuclear translocation.The NF-kappa B precursor p105 and the proto-oncogene product Bcl-3 are I kappa B molecules and control nuclear translocation of NF-kappa BThe glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domainThe bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent mannerPurification, reconstitution, and I kappa B association of the c-Rel-p65 (RelA) complex, a strong activator of transcriptionRegulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-kappa B/Rel transcription factorsControl of NF-kappa B transcriptional activation by signal induced proteolysis of I kappa B alphaTax induces nuclear translocation of NF-kappa B through dissociation of cytoplasmic complexes containing p105 or p100 but does not induce degradation of I kappa B alpha/MAD3Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa BTumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activationDNA binding alters the protease susceptibility of the p50 subunit of NF-kappa B.Mechanisms directing the nuclear localization of the CtBP family proteins.Transcription factor NF-kappaB is transported to the nucleus via cytoplasmic dynein/dynactin motor complex in hippocampal neurons.The NF-kappa B p50 precursor, p105, contains an internal I kappa B-like inhibitor that preferentially inhibits p50.N-myc suppresses major histocompatibility complex class I gene expression through down-regulation of the p50 subunit of NF-kappa B.Dissection of a novel nuclear localization signal in open reading frame 29 of varicella-zoster virus.The truncation that generated the v-cbl oncogene reveals an ability for nuclear transport, DNA binding and acute transformation.A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation.The oncoprotein Bcl-3 can facilitate NF-kappa B-mediated transactivation by removing inhibiting p50 homodimers from select kappa B sites.Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62.Proteolytic degradation of MAD3 (I kappa B alpha) and enhanced processing of the NF-kappa B precursor p105 are obligatory steps in the activation of NF-kappa B.The C terminus of the NF-kappa B p50 precursor and an I kappa B isoform contain transcription activation domains.Posttranslational modification and cell type-specific degradation of varicella-zoster virus ORF29p.Hepatitis B virus HBx protein activates transcription factor NF-kappaB by acting on multiple cytoplasmic inhibitors of rel-related proteinsAlterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.Cytoplasmic retention of Xenopus nuclear factor 7 before the mid blastula transition uses a unique anchoring mechanism involving a retention domain and several phosphorylation sites.Ligand-induced desensitization of interleukin 1 receptor-initiated intracellular signaling events in T helper lymphocytes.Dissociation of the dorsal-cactus complex and phosphorylation of the dorsal protein correlate with the nuclear localization of dorsal.Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.Rearranged NFKB-2 genes in lymphoid neoplasms code for constitutively active nuclear transactivators.Finely tuned regulation of cytoplasmic retention of Xenopus nuclear factor 7 by phosphorylation of individual threonine residues.Regulated nuclear import of the Drosophila rel protein dorsal: structure-function analysis.IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice.The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers.Heterologous C-terminal sequences disrupt transcriptional activation and oncogenesis by p59v-rel.An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation
P2860
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P2860
Cytoplasmic retention, DNA binding and processing of the NF-kappa B p50 precursor are controlled by a small region in its C-terminus
description
1991 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1991
@ast
im Dezember 1991 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1991/12/01)
@sk
vědecký článek publikovaný v roce 1991
@cs
wetenschappelijk artikel (gepubliceerd op 1991/12/01)
@nl
наукова стаття, опублікована в грудні 1991
@uk
مقالة علمية (نشرت في ديسمبر 1991)
@ar
name
Cytoplasmic retention, DNA bin ...... small region in its C-terminus
@ast
Cytoplasmic retention, DNA bin ...... small region in its C-terminus
@en
Cytoplasmic retention, DNA bin ...... small region in its C-terminus
@nl
type
label
Cytoplasmic retention, DNA bin ...... small region in its C-terminus
@ast
Cytoplasmic retention, DNA bin ...... small region in its C-terminus
@en
Cytoplasmic retention, DNA bin ...... small region in its C-terminus
@nl
prefLabel
Cytoplasmic retention, DNA bin ...... small region in its C-terminus
@ast
Cytoplasmic retention, DNA bin ...... small region in its C-terminus
@en
Cytoplasmic retention, DNA bin ...... small region in its C-terminus
@nl
P2093
P2860
P1433
P1476
Cytoplasmic retention, DNA bin ...... small region in its C-terminus
@en
P2093
P2860
P304
P407
P577
1991-12-01T00:00:00Z