Secretion-capture role for apolipoprotein E in remnant lipoprotein metabolism involving cell surface heparan sulfate proteoglycans
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Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnantsIdentification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1The effect of old age on apolipoprotein E and its receptors in rat liverCyclosporin A decreases apolipoprotein E secretion from human macrophages via a protein phosphatase 2B-dependent and ATP-binding cassette transporter A1 (ABCA1)-independent pathway.Obesity favors apolipoprotein E- and C-III-containing high density lipoprotein subfractions associated with risk of heart diseaseReceptors, mediators, and mechanisms involved in bacterial sepsis and septic shock.Decreased selective uptake of high density lipoprotein cholesteryl esters in apolipoprotein E knock-out miceDominant expression of type III hyperlipoproteinemia. Pathophysiological insights derived from the structural and kinetic characteristics of ApoE-1 (Lys146-->Glu).Human ApoA-II inhibits the hydrolysis of HDL triglyceride and the decrease of HDL size induced by hypertriglyceridemia and cholesteryl ester transfer protein in transgenic miceAntisense inhibition of apoB synthesis with mipomersen reduces plasma apoC-III and apoC-III-containing lipoproteinsRemnant lipoproteins inhibit malaria sporozoite invasion of hepatocytes.Vitamin K nutrition, metabolism, and requirements: current concepts and future research.Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycansDietary monounsaturated fat activates metabolic pathways for triglyceride-rich lipoproteins that involve apolipoproteins E and C-IIIModification by acrolein, a component of tobacco smoke and age-related oxidative stress, mediates functional impairment of human apolipoprotein E.Apolipoprotein e sets the stage: response to injury triggers neuropathology.Genetic variation and atherosclerosis.Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytesAn apolipoprotein E synthetic peptide targets to lipoproteins in plasma and mediates both cellular lipoprotein interactions in vitro and acute clearance of cholesterol-rich lipoproteins in vivo.Phenotype-dependent differences in apolipoprotein E metabolism and in cholesterol homeostasis in human monocyte-derived macrophagesLipoprotein lipase- and hepatic triglyceride lipase- promoted very low density lipoprotein degradation proceeds via an apolipoprotein E-dependent mechanism.Hepatic apo E expression is required for remnant lipoprotein clearance in the absence of the low density lipoprotein receptor.Increased expression of apolipoprotein E in transgenic rabbits results in reduced levels of very low density lipoproteins and an accumulation of low density lipoproteins in plasma.Cholesterol lowering in low density lipoprotein receptor knockout mice overexpressing apolipoprotein E.HIV-1 TAT inhibits microglial phagocytosis of Abeta peptide.Nascent very-low-density lipoprotein triacylglycerol hydrolysis by lipoprotein lipase is inhibited by apolipoprotein E in a dose-dependent manner.Atherogenic remnant lipoproteins: role for proteoglycans in trapping, transferring, and internalizing.chylomicron remnant + apoE => chylomicron remnant:apoE complexchylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complexchylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent)
P2860
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P2860
Secretion-capture role for apolipoprotein E in remnant lipoprotein metabolism involving cell surface heparan sulfate proteoglycans
description
1994 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1994
@ast
im Januar 1994 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/01/28)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/01/28)
@nl
наукова стаття, опублікована в січні 1994
@uk
name
Secretion-capture role for apo ...... heparan sulfate proteoglycans
@ast
Secretion-capture role for apo ...... heparan sulfate proteoglycans
@en
Secretion-capture role for apo ...... heparan sulfate proteoglycans
@nl
type
label
Secretion-capture role for apo ...... heparan sulfate proteoglycans
@ast
Secretion-capture role for apo ...... heparan sulfate proteoglycans
@en
Secretion-capture role for apo ...... heparan sulfate proteoglycans
@nl
prefLabel
Secretion-capture role for apo ...... heparan sulfate proteoglycans
@ast
Secretion-capture role for apo ...... heparan sulfate proteoglycans
@en
Secretion-capture role for apo ...... heparan sulfate proteoglycans
@nl
P2093
P921
P1476
Secretion-capture role for apo ...... heparan sulfate proteoglycans
@en
P2093
P304
P407
P577
1994-01-28T00:00:00Z