Delta-1 activation of notch-1 signaling results in HES-1 transactivation.
about
Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptorsCyclic stretch stimulates vascular smooth muscle cell alignment by redox-dependent activation of Notch3Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptorDifferential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiationThe p53 family member genes are involved in the Notch signal pathwayIntegrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.Notch signaling induces rapid degradation of achaete-scute homolog 1.Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterationsThe nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathwayThyroid hormone, brain development, and the environment.Human SRCAP and Drosophila melanogaster DOM are homologs that function in the notch signaling pathway.SHARP is a novel component of the Notch/RBP-Jkappa signalling pathway.p300 acts as a transcriptional coactivator for mammalian Notch-1SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradationBinding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2IkappaBalpha and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFkappaB pathwaysHERP, a new primary target of Notch regulated by ligand bindingDelta-1 enhances marrow and thymus repopulating ability of human CD34(+)CD38(-) cord blood cellsBasic helix-loop-helix transcription factors and enteroendocrine cell differentiationThe Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretaseLoss of negative regulation by Numb over Notch is relevant to human breast carcinogenesisHES6 acts as a transcriptional repressor in myoblasts and can induce the myogenic differentiation programImpaired neural differentiation of induced pluripotent stem cells generated from a mouse model of Sandhoff diseaseMouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methodsNotch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse developmentHes1 and Hes5 as notch effectors in mammalian neuronal differentiation.Multiple requirements for Hes 1 during early eye formationContext-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In VivoPremature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutantsO-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand functionO-fucosylation of DLL3 is required for its function during somitogenesisPatterns of Jagged1, Jagged2, Delta-like 1 and Delta-like 3 expression during late embryonic and postnatal brain development suggest multiple functional roles in progenitors and differentiated cellsAlterations of Notch/Jagged mRNA and protein expression after partial hepatectomy in ratsCharacterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line.Coordinate Notch3-hairy-related transcription factor pathway regulation in response to arterial injury. Mediator role of platelet-derived growth factor and ERKRbm15 modulates Notch-induced transcriptional activation and affects myeloid differentiationPremature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1Calcium depletion dissociates and activates heterodimeric notch receptorsGeneration of structurally and functionally distinct factors from the basic helix-loop-helix gene Hes3 by alternative first exons.OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development.
P2860
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P2860
Delta-1 activation of notch-1 signaling results in HES-1 transactivation.
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Delta-1 activation of notch-1 signaling results in HES-1 transactivation
@nl
Delta-1 activation of notch-1 signaling results in HES-1 transactivation.
@ast
Delta-1 activation of notch-1 signaling results in HES-1 transactivation.
@en
type
label
Delta-1 activation of notch-1 signaling results in HES-1 transactivation
@nl
Delta-1 activation of notch-1 signaling results in HES-1 transactivation.
@ast
Delta-1 activation of notch-1 signaling results in HES-1 transactivation.
@en
prefLabel
Delta-1 activation of notch-1 signaling results in HES-1 transactivation
@nl
Delta-1 activation of notch-1 signaling results in HES-1 transactivation.
@ast
Delta-1 activation of notch-1 signaling results in HES-1 transactivation.
@en
P2093
P2860
P3181
P356
P1476
Delta-1 activation of notch-1 signaling results in HES-1 transactivation
@en
P2093
C F Strong
E Hirsinger
N G Seidah
S Jarriault
P2860
P304
P3181
P356
10.1128/MCB.18.12.7423
P407
P577
1998-12-01T00:00:00Z