about
Retinoblastoma tumor suppressor functions shared by stem cell and cancer cell strategiesRB1: a prototype tumor suppressor and an enigmaThe multiple connections between pRB and cell metabolismDisruptive chemicals, senescence and immortalityDrugging the addict: non-oncogene addiction as a target for cancer therapyProteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylationLoss of dE2F compromises mitochondrial functionMechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.Hyperactivated Wnt signaling induces synthetic lethal interaction with Rb inactivation by elevating TORC1 activities.Regulation of cell transformation by Rb-controlled redox homeostasis.Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addictionIdentification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells.Deficiencies in Cellular Processes Modulated by the Retinoblastoma Protein Do Not Account for Reduced Human Cytomegalovirus Replication in Its AbsenceActivated E2F activity induces cell death in papillary thyroid carcinoma K1 cells with enhanced Wnt signalingRecruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression.E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis.Metabolic Reprogramming of Pancreatic Cancer Mediated by CDK4/6 Inhibition Elicits Unique VulnerabilitiesRB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation.Skp2 suppresses apoptosis in Rb1-deficient tumours by limiting E2F1 activity.Antitumor mechanisms when pRb and p53 are genetically inactivated.The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity.LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.A relative quantitative positive/negative ion switching method for untargeted lipidomics via high resolution LC-MS/MS from any biological source.Triomics Analysis of Imatinib-Treated Myeloma Cells Connects Kinase Inhibition to RNA Processing and Decreased Lipid Biosynthesis.Integrin-linked kinase regulates senescence in an Rb-dependent manner in cancer cell lines.Glutamine Metabolism in Cancer: Understanding the Heterogeneity.Exploring cancer metabolism using stable isotope-resolved metabolomics (SIRM).Glucose-dependent anaplerosis in cancer cells is required for cellular redox balance in the absence of glutamine.The intersection of RB tumor suppressor function, stem cells, metabolism and inflammation.Genome-Wide Analysis of Drosophila RBf2 Protein Highlights the Diversity of RB Family Targets and Possible Role in Regulation of Ribosome BiosynthesisDefining a new vision for the retinoblastoma gene: report from the 3rd International Rb MeetingRB in glutamine metabolism.Cancer metabolism: feeding a worm to starve a tumor.Defects in a new class of sulfate/anion transporter link sulfur acclimation responses to intracellular glutathione levels and cell cycle control.The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival.Glutamine Synthetase: Localization Dictates Outcome.RNA-Sequencing of Primary Retinoblastoma Tumors Provides New Insights and Challenges Into Tumor Development.Mitochondrial dysfunction in cancer
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Loss of RBF1 changes glutamine catabolism
@ast
Loss of RBF1 changes glutamine catabolism
@en
Loss of RBF1 changes glutamine catabolism
@nl
type
label
Loss of RBF1 changes glutamine catabolism
@ast
Loss of RBF1 changes glutamine catabolism
@en
Loss of RBF1 changes glutamine catabolism
@nl
prefLabel
Loss of RBF1 changes glutamine catabolism
@ast
Loss of RBF1 changes glutamine catabolism
@en
Loss of RBF1 changes glutamine catabolism
@nl
P2093
P2860
P3181
P356
P1433
P1476
Loss of RBF1 changes glutamine catabolism
@en
P2093
Andreas M Heilmann
Brandon N Nicolay
Gregory Stephanopoulos
John M Asara
Katrin Tschöp
Michael Korenjak
Nicholas J Dyson
Othon Iliopoulos
Paulo A Gameiro
P2860
P304
P3181
P356
10.1101/GAD.206227.112
P407
P577
2013-01-15T00:00:00Z