Active PI3K pathway causes an invasive phenotype which can be reversed or promoted by blocking the pathway at divergent nodes
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Reverse causal reasoning: applying qualitative causal knowledge to the interpretation of high-throughput data.Anti-EGFR antibody reduces lung nodules by inhibition of EGFR-pathway in a model of lymphangioleiomyomatosis.Everolimus restrains the paracrine pro-osteoclast activity of breast cancer cells.PIK3CA dependence and sensitivity to therapeutic targeting in urothelial carcinoma.Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare MutationsLentiviral vector PLV-PI3KCG gene transfer inhibits hypoxic cardiomyocytes apoptosis.Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies.Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling.Signaling via class IA Phosphoinositide 3-kinases (PI3K) in human, breast-derived cell linesImpact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas.Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds.PI3K in cancer-stroma interactions: bad in seed and ugly in soil.NOV is upregulated and promotes migration and invasion in bladder cancer.Insulin like growth factor binding protein 4 promotes GBM progression and regulates key factors involved in EMT and invasion.The role of autophagy in the cross-talk between epithelial-mesenchymal transitioned tumor cells and cancer stem-like cells.Extract of Perilla frutescens inhibits tumor proliferation of HCC via PI3K/AKT signal pathway.PAK1 mediates pancreatic cancer cell migration and resistance to MET inhibition.Phosphorylated ribosomal protein S6 correlation with p21 expression and inverse association with tumor size in oral squamous cell carcinoma.
P2860
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P2860
Active PI3K pathway causes an invasive phenotype which can be reversed or promoted by blocking the pathway at divergent nodes
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Active PI3K pathway causes an ...... the pathway at divergent nodes
@ast
Active PI3K pathway causes an ...... the pathway at divergent nodes
@en
Active PI3K pathway causes an ...... the pathway at divergent nodes
@nl
type
label
Active PI3K pathway causes an ...... the pathway at divergent nodes
@ast
Active PI3K pathway causes an ...... the pathway at divergent nodes
@en
Active PI3K pathway causes an ...... the pathway at divergent nodes
@nl
prefLabel
Active PI3K pathway causes an ...... the pathway at divergent nodes
@ast
Active PI3K pathway causes an ...... the pathway at divergent nodes
@en
Active PI3K pathway causes an ...... the pathway at divergent nodes
@nl
P2093
P2860
P50
P3181
P1433
P1476
Active PI3K pathway causes an ...... the pathway at divergent nodes
@en
P2093
Anthony C Torres
Christopher Torrance
Jeffrey J Wallin
John E Goodall
Klaus P Hoeflich
Kyla M Grimshaw
Kyle A Edgar
Lori S Friedman
Marcia Belvin
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0036402
P407
P577
2012-01-01T00:00:00Z