Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix components
about
Protoporphyrins enhance oligomerization and enzymatic activity of HtrA1 serine proteaseAlpha-1-antitrypsin: a novel human high temperature requirement protease A1 (HTRA1) substrate in human placental tissueSynonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling.Variants at chromosome 10q26 locus and the expression of HTRA1 in the retina.Comparison of drusen and modifying genes in autosomal dominant radial drusen and age-related macular degeneration.Gene expression in Atlantic salmon skin in response to infection with the parasitic copepod Lepeophtheirus salmonis, cortisol implant, and their combinationStudying age-related macular degeneration using animal models.Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signalingDysregulation of protease and protease inhibitors in a mouse model of human pelvic organ prolapse.Interaction of complement factor h and fibulin3 in age-related macular degenerationSerine protease HTRA1 antagonizes transforming growth factor-β signaling by cleaving its receptors and loss of HTRA1 in vivo enhances bone formationHTRA1 (high temperature requirement A serine peptidase 1) gene is transcriptionally regulated by insertion/deletion nucleotides located at the 3' end of the ARMS2 (age-related maculopathy susceptibility 2) gene in patients with age-related macular dJoint Effect of CFH and ARMS2/HTRA1 Polymorphisms on Neovascular Age-Related Macular Degeneration in Chinese PopulationRestoration of mesenchymal retinal pigmented epithelial cells by TGFβ pathway inhibitors: implications for age-related macular degenerationGenetic insights into age-related macular degeneration: controversies addressing risk, causality, and therapeutics.Angiographic features of transgenic mice with increased expression of human serine protease HTRA1 in retinal pigment epitheliumThe differential role of HTRA1 in HPV-positive and HPV-negative cervical cell line proliferationAge-related macular degeneration-associated silent polymorphisms in HtrA1 impair its ability to antagonize insulin-like growth factor 1.Oxidative stress, innate immunity, and age-related macular degenerationCumulative association between age-related macular degeneration and less studied genetic variants in PLEKHA1/ARMS2/HTRA1: a meta and gene-cluster analysisHigh temperature requirement A1 and fibronectin: two possible players in placental tissue remodelling.Low-density lipoprotein receptor-related protein-1: role in the regulation of vascular integrity.Highly penetrant alleles in age-related macular degeneration.Roles of exosomes in the normal and diseased eye.Protective effects of an HTRA1 insertion-deletion variant against age-related macular degeneration in the Chinese populations.Inhibition of cell proliferation and migration after HTRA1 knockdown in retinal pigment epithelial cells.Overexpression of HTRA1 leads to down-regulation of fibronectin and functional changes in RF/6A cells and HUVECs.Novel Function of Serine Protease HTRA1 in Inhibiting Adipogenic Differentiation of Human Mesenchymal Stem Cells via MAP Kinase-Mediated MMP Upregulation.The salt-sensitive structure and zinc inhibition of Borrelia burgdorferi protease BbHtrA.LRP1 protects the vasculature by regulating levels of connective tissue growth factor and HtrA1Determinants of amyloid fibril degradation by the PDZ protease HTRA1.Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates.Guest editorial: visionary genomics.A69S and R38X ARMS2 and Y402H CFH gene polymorphisms as risk factors for neovascular age-related macular degeneration in Poland - a brief report.A functional approach to examine the role of HTRA1 versus ARMS2 in AMD.HtrA1 activation is driven by an allosteric mechanism of inter-monomer communication.Lipopolysaccharide increases the incidence of collagen-induced arthritis in mice through induction of protease HTRA-1 expression.Macrophage migration inhibitory factor (MIF) modulates trophic signaling through interaction with serine protease HTRA1.Borrelia burgdorferi BbHtrA degrades host ECM proteins and stimulates release of inflammatory cytokines in vitro.Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair.
P2860
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P2860
Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix components
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Overexpression of HTRA1 leads ...... xtracellular matrix components
@ast
Overexpression of HTRA1 leads ...... xtracellular matrix components
@en
Overexpression of HTRA1 leads ...... xtracellular matrix components
@nl
type
label
Overexpression of HTRA1 leads ...... xtracellular matrix components
@ast
Overexpression of HTRA1 leads ...... xtracellular matrix components
@en
Overexpression of HTRA1 leads ...... xtracellular matrix components
@nl
prefLabel
Overexpression of HTRA1 leads ...... xtracellular matrix components
@ast
Overexpression of HTRA1 leads ...... xtracellular matrix components
@en
Overexpression of HTRA1 leads ...... xtracellular matrix components
@nl
P2093
P2860
P3181
P1433
P1476
Overexpression of HTRA1 leads ...... xtracellular matrix components
@en
P2093
Philipp S Muether
Sarah Vierkotten
Sascha Fauser
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0022959
P407
P577
2011-01-01T00:00:00Z