A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice
about
The Alzheimer's amyloid-degrading peptidase, neprilysin: can we control it?The emerging role of the mitochondrial-derived peptide humanin in stress resistanceSH3-binding protein 5 mediates the neuroprotective effect of the secreted bioactive peptide humanin by inhibiting c-Jun NH2-terminal kinaseMitochondrial stress signaling in longevity: a new role for mitochondrial function in agingS14G-humanin restored cellular homeostasis disturbed by amyloid-beta proteinHumanin: a harbinger of mitochondrial-derived peptides?S14G-humanin inhibits Aβ1-42 fibril formation, disaggregates preformed fibrils, and protects against Aβ-induced cytotoxicity in vitro.Humanin and age-related diseases: a new link?Humanin binds MPP8: mapping interaction sites of the peptide and protein.Secreted calmodulin-like skin protein inhibits neuronal death in cell-based Alzheimer's disease models via the heterotrimeric Humanin receptorPharmacokinetics and tissue distribution of humanin and its analogues in male rodents.Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer's DiseaseThe mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus.Protective effects of Humanin and calmodulin-like skin protein in Alzheimer's disease and broad range of abnormalities.Impact of Insulin Degrading Enzyme and Neprilysin in Alzheimer's Disease Biology: Characterization of Putative Cognates for Therapeutic Applications.Humanin: Functional Interfaces with IGF-I.Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells.Humanin attenuates Alzheimer-like cognitive deficits and pathological changes induced by amyloid β-peptide in ratsHumanin Specifically Interacts with Amyloid-β Oligomers and Counteracts Their in vivo Toxicity.Humanin decreases mitochondrial membrane permeability by inhibiting the membrane association and oligomerization of Bax and Bid proteins.Calmodulin-like skin protein protects against spatial learning impairment in a mouse model of Alzheimer disease.Humanin (HN) and glucose transporter 8 (GLUT8) in pregnancies complicated by intrauterine growth restriction.Intracerebroventricular Administration of L-arginine Improves Spatial Memory Acquisition in Triple Transgenic Mice Via Reduction of Oxidative Stress and Apoptosis.Humanin Prevents Age-Related Cognitive Decline in Mice and is Associated with Improved Cognitive Age in HumansImportance of GPCR-Mediated Microglial Activation in Alzheimer's Disease
P2860
Q21296650-4213185F-9334-4DB7-9E21-2179C6AB5219Q24602234-664A5619-A1CC-4929-9203-71903327D81BQ30009605-FFB11287-50D2-4528-AA29-BF068BE46F73Q34085957-DC0AC09A-120A-4855-8A85-2431C5DD3AF6Q34094639-FA956186-A244-41FC-87EE-667376FF0C42Q34327412-1A25E93D-7937-4659-8C3D-F1E284141CBFQ34561747-CE958546-3829-4A2D-890C-F5A566B0F6D1Q34631026-D5A6CA55-5038-4530-BD4D-10B8F7BBAC1AQ34637404-02DA7BA5-7B23-43BD-9A58-5DD9FE238C76Q36738098-D2B3A73B-D46B-4B26-8A67-CC97781772CFQ37181873-3DED228D-D766-4BE5-BA23-5C713D52CC06Q37408544-D6E5C569-9713-48CD-984B-7541DE9521A8Q37564985-2CC23549-119A-4B49-8D9B-C3489057CD88Q38223607-5EC1C37A-64AC-4DBC-9727-3B2A80471C82Q38601445-73393AA9-49A0-400D-A97E-C8B687E22A74Q38809118-D8F9B484-A472-4B3E-B19E-6ECF977F9501Q41319863-7488B68E-AD56-4106-AA36-8EB685224866Q41457813-ED80EC5E-5A06-4611-BD5D-B114C0415ED9Q46405748-A716846D-7DB4-42A7-BBDF-42EB94BE117DQ47267139-F3D3CA0C-7330-4B2D-8CD0-732D0D2F0910Q47375015-13832A4C-989B-40AA-B90A-5A277FF43291Q52625664-59F6E891-AEC6-4BC8-9700-453250A0D4DEQ54968348-CC05EC7B-434F-46DC-829C-B9B4310AC729Q58705968-F0BD168B-4178-432D-96DB-D3521C98699AQ58729326-F67890C8-F07A-452C-931F-730C8FF34A35
P2860
A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A humanin derivative reduces a ...... icit in triple transgenic mice
@ast
A humanin derivative reduces a ...... icit in triple transgenic mice
@en
A humanin derivative reduces a ...... icit in triple transgenic mice
@nl
type
label
A humanin derivative reduces a ...... icit in triple transgenic mice
@ast
A humanin derivative reduces a ...... icit in triple transgenic mice
@en
A humanin derivative reduces a ...... icit in triple transgenic mice
@nl
prefLabel
A humanin derivative reduces a ...... icit in triple transgenic mice
@ast
A humanin derivative reduces a ...... icit in triple transgenic mice
@en
A humanin derivative reduces a ...... icit in triple transgenic mice
@nl
P2093
P2860
P3181
P1433
P1476
A humanin derivative reduces a ...... icit in triple transgenic mice
@en
P2093
Chiho Hirata-Fukae
Elkhansa Sidahmed
Takako Niikura
Yasuji Matsuoka
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0016259
P407
P577
2011-01-17T00:00:00Z