Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer's Disease
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Clearance systems in the brain-implications for Alzheimer diseaseThe Impact of Vitamin E and Other Fat-Soluble Vitamins on Alzheimer´s DiseaseBiological mechanisms underlying the ultraviolet radiation-induced formation of skin wrinkling and sagging II: over-expression of neprilysin plays an essential roleIn silico design of BACE1 inhibitor for Alzheimer's disease by traditional Chinese medicine.Alzheimer's disease: relevant molecular and physiopathological events affecting amyloid-β brain balance and the putative role of PPARs.Mitofusin-2 knockdown increases ER-mitochondria contact and decreases amyloid β-peptide productionGranulocyte-colony stimulating factor attenuates oligomeric amyloid β neurotoxicity by activation of neprilysin.Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer's disease.Prion Disease Induces Alzheimer Disease-Like Neuropathologic Changes.Dynamic alteration of neprilysin and endothelin-converting enzyme in age-dependent APPswe/PS1dE9 mouse model of Alzheimer's disease.APP Function and Lipids: A Bidirectional Link.Amyloid-clearing proteins and their epigenetic regulation as a therapeutic target in Alzheimer's disease.β-Amyloid peptides and amyloid plaques in Alzheimer's disease."Boomerang Neuropathology" of Late-Onset Alzheimer's Disease is Shrouded in Harmful "BDDS": Breathing, Diet, Drinking, and Sleep During Aging.Neprilysin gene transfer: A promising therapeutic approach for Alzheimer's disease.Regenerative therapy for hippocampal degenerative diseases: lessons from preclinical studies.New Insights into Epigenetic and Pharmacological Regulation of Amyloid-Degrading Enzymes.Vitamin E: Curse or Benefit in Alzheimer's Disease? A Systematic Investigation of the Impact of α-, γ- and δ-Tocopherol on Aß Generation and Degradation in Neuroblastoma Cells.Epithelial-mesenchymal interaction mechanisms leading to the over-expression of neprilysin are involved in the UVB-induced formation of wrinkles in the skin.Activation of 5-HT(2C) receptor promotes the expression of neprilysin in U251 human glioma cells.Omega-3 fatty acids, lipids and apoE lipidation in Alzheimer's disease: a rationale for multi-nutrient dementia prevention.The anti-inflammatory Annexin A1 induces the clearance and degradation of the amyloid-β peptide.Organotypic vibrosections from whole brain adult Alzheimer mice (overexpressing amyloid-precursor-protein with the Swedish-Dutch-Iowa mutations) as a model to study clearance of beta-amyloid plaques.Neuroprotective effects of the anticancer drug NVP-BEZ235 (dactolisib) on amyloid-β 1-42 induced neurotoxicity and memory impairment.APP intracellular domain derived from amyloidogenic β- and γ-secretase cleavage regulates neprilysin expression.Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein.Role of Notch-1 signaling pathway in PC12 cell apoptosis induced by amyloid beta-peptide (25-35)Synthesis, secretion, function, metabolism and application of natriuretic peptides in heart failure.The relationship between cholesterol level and Alzheimer's disease-associated APP proteolysis/Aβ metabolism.The nuclear transportation routes of membrane-bound transcription factors.Tongluo Xingnao effervescent tablet reverses memory deficit and reduces plaque load in APPswe/PS1dE9 mice.Modulation of the expression of genes related to the system of amyloid-beta metabolism in the brain as a novel mechanism of ceftriaxone neuroprotective properties.
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P2860
Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer's Disease
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 December 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Neprilysin and Aβ Clearance: I ...... cations in Alzheimer's Disease
@en
Neprilysin and Aβ Clearance: I ...... ations in Alzheimer's Disease.
@nl
type
label
Neprilysin and Aβ Clearance: I ...... cations in Alzheimer's Disease
@en
Neprilysin and Aβ Clearance: I ...... ations in Alzheimer's Disease.
@nl
prefLabel
Neprilysin and Aβ Clearance: I ...... cations in Alzheimer's Disease
@en
Neprilysin and Aβ Clearance: I ...... ations in Alzheimer's Disease.
@nl
P2093
P2860
P356
P1476
Neprilysin and Aβ Clearance: I ...... cations in Alzheimer's Disease
@en
P2093
Christoph P Stahlmann
Janine Mett
Valerie C Zimmer
Viola J Haupenthal
P2860
P356
10.3389/FNAGI.2013.00098
P577
2013-12-23T00:00:00Z