Cell-type-specific activation and repression of PU.1 by a complex of discrete, functionally specialized cis-regulatory elements
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Regulatory gene network circuits underlying T cell development from multipotent progenitorsThe RUNX1 +24 enhancer and P1 promoter identify a unique subpopulation of hematopoietic progenitor cells derived from human pluripotent stem cellsA far downstream enhancer for murine Bcl11b controls its T-cell specific expressionTranscriptional establishment of cell-type identity: dynamics and causal mechanisms of T-cell lineage commitment.Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitmentBcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network.GATA-3 dose-dependent checkpoints in early T cell commitment.Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.Irreversibility of T-Cell Specification: Insights from Computational Modelling of a Minimal Network Architecture.Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosisPositive feedback between PU.1 and the cell cycle controls myeloid differentiationMultilayered specification of the T-cell lineage fate.T cell lineage commitment: identity and renunciation.Transcriptional control of early T and B cell developmental choicesDevelopmental gene networks: a triathlon on the course to T cell identity.Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control.Hematopoiesis and T-cell specification as a model developmental system.Cytokines, Transcription Factors, and the Initiation of T-Cell Development.FGFR3 is a target of the homeobox transcription factor SHOX in limb development.Distinct Genetic Networks Orchestrate the Emergence of Specific Waves of Fetal and Adult B-1 and B-2 Development.DNA methylation-mediated silencing of PU.1 in leukemia cells resistant to cell differentiation.Ikaros represses and activates PU.1 cell-type-specifically through the multifunctional Sfpi1 URE and a myeloid specific enhancer.Dynamic transformations of genome-wide epigenetic marking and transcriptional control establish T cell identity.Differential Expression of PU.1 and Key T Lineage Transcription Factors Distinguishes Fetal and Adult T Cell Development.Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding
P2860
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P2860
Cell-type-specific activation and repression of PU.1 by a complex of discrete, functionally specialized cis-regulatory elements
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Cell-type-specific activation ...... alized cis-regulatory elements
@ast
Cell-type-specific activation ...... alized cis-regulatory elements
@en
Cell-type-specific activation ...... alized cis-regulatory elements
@nl
type
label
Cell-type-specific activation ...... alized cis-regulatory elements
@ast
Cell-type-specific activation ...... alized cis-regulatory elements
@en
Cell-type-specific activation ...... alized cis-regulatory elements
@nl
prefLabel
Cell-type-specific activation ...... alized cis-regulatory elements
@ast
Cell-type-specific activation ...... alized cis-regulatory elements
@en
Cell-type-specific activation ...... alized cis-regulatory elements
@nl
P2860
P3181
P356
P1476
Cell-type-specific activation ...... alized cis-regulatory elements
@en
P2093
Mark A Zarnegar
P2860
P304
P3181
P356
10.1128/MCB.00354-10
P407
P577
2010-10-01T00:00:00Z