about
LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory elementComplement C1q activates canonical Wnt signaling and promotes aging-related phenotypesβ-catenin/TCF-1 pathway in T cell development and differentiationWnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia developmentStimulation of Wnt/ß-catenin pathway in human CD8+ T lymphocytes from blood and lung tumors leads to a shared young/memory phenotypePharmacological inhibition of glycogen synthase kinase 3 regulates T cell development in vitroLoss of adenomatous polyposis coli gene function disrupts thymic developmentWnt/beta-catenin signaling is required for development of the exocrine pancreasCell-type-specific activation and repression of PU.1 by a complex of discrete, functionally specialized cis-regulatory elementsWnt signalling in stem cells and cancerT cell factor 1 regulates thymocyte survival via a RORγt-dependent pathwayWnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration.Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner.β-Catenin promotes colitis and colon cancer through imprinting of proinflammatory properties in T cells.T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma.Stabilisation of β-catenin downstream of T cell receptor signalling.TCF1 and beta-catenin regulate T cell development and functionEssential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory.Human FasL gene is a target of β-catenin/T-cell factor pathway and complex FasL haplotypes alter promoter functions.Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1Dysregulation of Frizzled 6 is a critical component of B-cell leukemogenesis in a mouse model of chronic lymphocytic leukemia.Suppressive regulatory T cell activity is potentiated by glycogen synthase kinase 3{beta} inhibitionWnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules.The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas.αβ versus γδ fate choice: counting the T-cell lineages at the branch point.A critical role for the regulated wnt-myc pathway in naive T cell survivalT cell factor-1 controls the lifetime of CD4+ CD8+ thymocytes in vivo and distal T cell receptor α-chain rearrangement required for NKT cell developmentβ-Catenin is required for the differentiation of iNKT2 and iNKT17 cells that augment IL-25-dependent lung inflammation.MicroRNA-142-3p Negatively Regulates Canonical Wnt Signaling Pathway.T cell factor-1 and β-catenin control the development of memory-like CD8 thymocytes.Establishment and functioning of intrathymic microenvironments.T-cell development: an extrathymic perspective.Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor.At the crossroads: diverse roles of early thymocyte transcriptional regulators.Beta-catenin/Tcf determines the outcome of thymic selection in response to alphabetaTCR signaling.Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo.Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivoMolecular basis for the tissue specificity of β-catenin oncogenesis.Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development.
P2860
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P2860
description
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Dezember 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/12/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/12/01)
@nl
наукова стаття, опублікована в грудні 2003
@uk
مقالة علمية (نشرت في ديسمبر 2003)
@ar
name
Deletion of beta-catenin impairs T cell development
@ast
Deletion of beta-catenin impairs T cell development
@en
Deletion of beta-catenin impairs T cell development
@nl
type
label
Deletion of beta-catenin impairs T cell development
@ast
Deletion of beta-catenin impairs T cell development
@en
Deletion of beta-catenin impairs T cell development
@nl
prefLabel
Deletion of beta-catenin impairs T cell development
@ast
Deletion of beta-catenin impairs T cell development
@en
Deletion of beta-catenin impairs T cell development
@nl
P2093
P3181
P356
P1433
P1476
Deletion of beta-catenin impairs T cell development
@en
P2093
Daliya Banerjee
Joerg Huelsken
Jyoti Misra Sen
Walter Birchmeier
Youyuan Xu
P304
P3181
P356
10.1038/NI1008
P407
P577
2003-12-01T00:00:00Z