Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers - Wikidata - awgldk - TriplyDB

Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers

Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers

http://www.wikidata.org/entity/Q28757672

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Molecular testing in lung cancer in the era of precision medicine Epidermal growth factor signaling in transformed cells Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines.Power to detect selective allelic amplification in genome-wide scans of tumor data.East meets West: ethnic differences in epidemiology and clinical behaviors of lung cancer between East Asians and Caucasians.Deregulated EGFR signaling during lung cancer progression: mutations, amplicons, and autocrine loops.Epidermal growth factor receptor polymorphisms and risk for toxicity in paediatric patients treated with gefitinib.Discovery of EST-SSRs in lung cancer: tagged ESTs with SSRs lead to differential amino acid and protein expression patterns in cancerous tissues.Functional EGFR germline polymorphisms may confer risk for EGFR somatic mutations in non-small cell lung cancer, with a predominant effect on exon 19 microdeletions Non-Small-Cell Lung Cancer Clinicopathologic Features and Survival Outcomes in Asian Pacific Islanders Residing in the United States: A SEER Analysis Epidermal growth factor receptor gene polymorphisms are associated with prognostic features of breast cancer Molecular epidemiology of lung cancer and geographic variations with special reference to EGFR mutations.Correlation between familial cancer history and epidermal growth factor receptor mutations in Taiwanese never smokers with non-small cell lung cancer: a case-control study.Lack of EGFR-activating mutations in European patients with triple-negative breast cancer could emphasise geographic and ethnic variations in breast cancer mutation profiles CA-SSR1 Polymorphism in Intron 1 of the EGFR Gene in Patients with Malignant Tumors Who Develop Acneiform Rash Associated with the Use of Cetuximab.Epidermal growth factor receptor abnormalities in the pathogenesis and progression of lung adenocarcinomas.Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer.EGFR mutation incidence in non-small-cell lung cancer of adenocarcinoma histology: a systematic review and global map by ethnicity (mutMapII).EGFR polymorphism as a predictor of clinical outcome in advanced lung cancer patients treated with EGFR-TKI.Polymorphisms in intron 1 of the EGFR gene in non-small cell lung cancer patients.Molecular genetic alterations in egfr CA-SSR-1 microsatellite and egfr copy number changes are associated with aggressiveness in thymoma.Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer.Chasing targets for EGFR tyrosine kinase inhibitors in non-small-cell lung cancer: Asian perspectives.Emerging ethnic differences in lung cancer therapy.Genetic predictors of MEK dependence in non-small cell lung cancer.EGFR-targeted therapies in lung cancer: predictors of response and toxicity -216G/T (rs712829), a functional variant of the EGFR promoter, is associated with the pleural metastasis of lung adenocarcinoma.EGFR pathway polymorphisms and bladder cancer susceptibility and prognosis.Effect of disrupting seven-in-absentia homolog 2 function on lung cancer cell growth Epidermal growth factor receptor (EGFR) polymorphisms and breast cancer among Hispanic and non-Hispanic white women: the Breast Cancer Health Disparities Study.Sequential molecular changes during multistage pathogenesis of small peripheral adenocarcinomas of the lung.The comparison of outcomes from tyrosine kinase inhibitor monotherapy in second- or third-line for advanced non-small-cell lung cancer patients with wild-type or unknown EGFR status Limited copy number-high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies Evaluation of 7q31 region improves the accuracy of EGFR FISH assay in non small cell lung cancer.The Pharmacogenetic Rescue of Side-Lined Anticancer Drugs to the Front-Line: Gefitinib as a Case Example.Differences in outcome and toxicity between Asian and caucasian patients with lung cancer treated with systemic therapy.EGF receptor-targeted therapy in non-small-cell lung cancer: role of germline polymorphisms in outcome and toxicity.Monoclonal antibodies in lung cancer.Class act: safety comparison of approved tyrosine kinase inhibitors for non-small-cell lung carcinoma.Gene expression of MAGE-A3 and PRAME tumor antigens and EGFR mutational status in Taiwanese non-small cell lung cancer patients.

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P2860

Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers

http://www.wikidata.org/entity/Q28757672

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2007 nî lūn-bûn

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2007年の論文

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Polymorphisms, mutations, and ...... in non-small cell lung cancers

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Polymorphisms, mutations, and ...... in non-small cell lung cancers

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Polymorphisms, mutations, and ...... in non-small cell lung cancers

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Adi F Gazdar

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Antonio Marchetti

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P2860

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib.

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers

HER-2, EGFR, COX-2 expression status correlated to microvessel density and survival in resected non-small cell lung cancer.

Modulation of EGFR gene transcription by secondary structures, a polymorphic repetitive sequence and mutations--a link between genetics and epigenetics.

Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins.

Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer.

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