Selection of target sites for mobile DNA integration in the human genome
about
HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiencyPrecision editing of large animal genomesA transposon and transposase system for human applicationThe Sleeping Beauty transposon system: a non-viral vector for gene therapyPreferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injectionLEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integrationApplications of DNA integrating elements: Facing the bias bullyAllosteric Inhibition of Human Immunodeficiency Virus IntegraseThe mechanism of retroviral integration from X-ray structures of its key intermediatesNMR structural analysis ofSleeping Beautytransposase binding to DNAAltering murine leukemia virus integration through disruption of the integrase and BET protein family interactionA new class of multimerization selective inhibitors of HIV-1 integraseIn vivo genome editing restores haemostasis in a mouse model of haemophiliaEndogenous non-retroviral RNA virus elements evidence a novel type of antiviral immunitypiRNAs derived from ancient viral processed pseudogenes as transgenerational sequence-specific immune memory in mammalsDNA transposon-based gene vehicles - scenes from an evolutionary driveComparative analysis of the recently discovered hAT transposon TcBuster in human cellsDirectly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latencyA nucleosomal surface defines an integration hotspot for the Saccharomyces cerevisiae Ty1 retrotransposonIntegration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data AnalysisRole of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting.EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic dataAlu and b1 repeats have been selectively retained in the upstream and intronic regions of genes of specific functional classes.Fidelity of target site duplication and sequence preference during integration of xenotropic murine leukemia virus-related virus.A functional screen for regulatory elements that improve retroviral vector gene expressionStem cell marking with promotor-deprived self-inactivating retroviral vectors does not lead to induced clonal imbalance.Genomic and functional assays demonstrate reduced gammaretroviral vector genotoxicity associated with use of the cHS4 chromatin insulator.Sleeping beauty transposition from nonintegrating lentivirus.GCN2 phosphorylates HIV-1 integrase and decreases HIV-1 replication by limiting viral integration.LEDGF hybrids efficiently retarget lentiviral integration into heterochromatin.Deciphering the code for retroviral integration target site selectionHigh-definition mapping of retroviral integration sites defines the fate of allogeneic T cells after donor lymphocyte infusion.The (r)evolution of SINE versus LINE distributions in primate genomes: sex chromosomes are important.HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2Stable transgene expression in primitive human CD34+ hematopoietic stem/progenitor cells, using the Sleeping Beauty transposon systemGenome-wide analysis of alpharetroviral integration in human hematopoietic stem/progenitor cells.Dynamics of gene-modified progenitor cells analyzed by tracking retroviral integration sites in a human SCID-X1 gene therapy trialMethods for integration site distribution analyses in animal cell genomesA gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing.LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes?
P2860
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P2860
Selection of target sites for mobile DNA integration in the human genome
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Selection of target sites for mobile DNA integration in the human genome
@ast
Selection of target sites for mobile DNA integration in the human genome
@en
Selection of target sites for mobile DNA integration in the human genome
@nl
type
label
Selection of target sites for mobile DNA integration in the human genome
@ast
Selection of target sites for mobile DNA integration in the human genome
@en
Selection of target sites for mobile DNA integration in the human genome
@nl
prefLabel
Selection of target sites for mobile DNA integration in the human genome
@ast
Selection of target sites for mobile DNA integration in the human genome
@en
Selection of target sites for mobile DNA integration in the human genome
@nl
P2860
P3181
P1476
Selection of target sites for mobile DNA integration in the human genome
@en
P2093
Charles Berry
Sridhar Hannenhalli
P2860
P3181
P356
10.1371/JOURNAL.PCBI.0020157
P407
P577
2006-11-24T00:00:00Z