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Epigenetics and human disease: translating basic biology into clinical applications

Epigenetics and human disease: translating basic biology into clinical applications

http://www.wikidata.org/entity/Q28768502

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Epigenetic modifications in cancer DNA Methyltransferase Activity Assays: Advances and Challenges A perspective on dietary phytochemicals and cancer chemoprevention: oxidative stress, nrf2, and epigenomics The emerging role of epigenetics in cardiovascular disease Epigenetics of Alzheimer's disease and frontotemporal dementia In utero alcohol exposure, epigenetic changes, and their consequences Considering maternal dietary modulators for epigenetic regulation and programming of the fetal epigenome Viruses and human breast cancer Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer Role of early life exposure and environment on neurodegeneration: implications on brain disorders Oxidative stress, epigenetics, and cancer stem cells in arsenic carcinogenesis and prevention Molecular Epidemiology, prenatal exposure and prevention of cancer The Neurobiology and Psychology of Pedophilia: Recent Advances and Challenges.In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma.Role of DNA methyltransferase 3A mRNA expression in Egyptian patients with idiopathic thrombocytopenic purpura.Multi-platform whole-genome microarray analyses refine the epigenetic signature of breast cancer metastasis with gene expression and copy number Abnormal DNA methylation as a cell-free circulating DNA biomarker for colorectal cancer detection: A review of literature.Influence of MTHFR Genetic Background on p16 and MGMT Methylation in Oral Squamous Cell Cancer Genome-wide Association Studies for Osteoporosis: A 2013 Update.Epigenetics in metal carcinogenesis: nickel, arsenic, chromium and cadmium.Effect of body mass index on global DNA methylation in healthy Korean women.Breast cancer proteomics: a review for clinicians.Pharmacogenomics of oral antidiabetic medications: current data and pharmacoepigenomic perspective.Choline's role in maintaining liver function: new evidence for epigenetic mechanisms.Epigenetic modulation of intestinal cholesterol transporter Niemann-Pick C1-like 1 (NPC1L1) gene expression by DNA methylation.An efficient high-throughput screening method for MYST family acetyltransferases, a new class of epigenetic drug targets.Epigenetic changes induced by curcumin and other natural compounds.Computational Epigenetics: the new scientific paradigm.Cellular reprogramming for understanding and treating human disease.DNA methylation and microRNA biomarkers for noninvasive detection of gastric and colorectal cancer.Expression profiling of DNA methylation-mediated epigenetic gene-silencing factors in breast cancer.Current progress in pharmacogenetics.Epigenetic regulation in alcoholic liver disease.Heavy metals and epigenetic alterations in brain tumors.Epigenetic regulation of human β-defensin 2 and CC chemokine ligand 20 expression in gingival epithelial cells in response to oral bacteria.Systems biology approach to stage-wise characterization of epigenetic genes in lung adenocarcinoma.Sexual dimorphism in ischemic stroke: lessons from the laboratory.Reduced DNA methylation at the PEG3 DMR and KvDMR1 loci in children exposed to alcohol in utero: a South African Fetal Alcohol Syndrome cohort study A potential use of embryonic stem cell medium for the in vitro culture of preimplantation embryos What's out there making us sick?

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Epigenetics and human disease: translating basic biology into clinical applications

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2006 nî lūn-bûn

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2006年の論文

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2006年論文

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Canadian Medical Association Journal

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Epigenetics and human disease: translating basic biology into clinical applications

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David Rodenhiser

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Mellissa Mann

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P2860

Chromatin dynamics at DNA replication, transcription and repair

Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation

Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.

In vitro fertilization may increase the risk of Beckwith-Wiedemann syndrome related to the abnormal imprinting of the KCN1OT gene

On the epigenetic regulation of the human reelin promoter

In psychosis, cortical interneurons overexpress DNA-methyltransferase 1

Current status of human chromosome 14

Promoter methylation of cyclin D2 gene in gastric carcinoma.

Disruption of imprinted gene methylation and expression in cloned preimplantation stage mouse embryos

Mutations in the gene encoding methyl-CpG-binding protein 2 cause Rett syndrome

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341-348

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10.1503/CMAJ.050774

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7328385

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