EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis
about
Multifaceted role of the polycomb-group gene EZH2 in hematological malignancies.The Expanding Role of the BCL6 Oncoprotein as a Cancer Therapeutic Target.Murine models of germinal center derived-lymphomas.Drug discovery and therapeutic delivery for the treatment of B and T cell tumors.Polycomb Repressor Complex 2 in Genomic Instability and CancerEZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loopEpithelial EZH2 serves as an epigenetic determinant in experimental colitis by inhibiting TNFα-mediated inflammation and apoptosis.EZH2 suppression in glioblastoma shifts microglia toward M1 phenotype in tumor microenvironment.The polycomb group protein BMI-1 inhibitor PTC-209 is a potent anti-myeloma agent alone or in combination with epigenetic inhibitors targeting EZH2 and the BET bromodomains.EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody Production.BCL6 as a therapeutic target for lymphoma.FBXL10 contributes to the development of diffuse large B-cell lymphoma by epigenetically enhancing ERK1/2 signaling pathway.Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies.Chromatin modifying gene mutations in follicular lymphoma.Epigenetic mechanisms in health and disease: BCEC 2017.Potential Epigenetic Regulation in the Germinal Center Reaction of Lymphoid Tissues in HIV/SIV Infection.A Non-canonical BCOR-PRC1.1 Complex Represses Differentiation Programs in Human ESCs.Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs.NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells.Transcription Factor Co-expression Networks of Adipose RNA-Seq Data Reveal Regulatory Mechanisms of Obesity
P2860
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P2860
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis
description
2016 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2016
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scientific journal article
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wetenschappelijk artikel (gepubliceerd op 2016/08/08)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в серпні 2016
@uk
مقالة علمية (نشرت في 8-8-2016)
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name
EZH2 and BCL6 Cooperate to Ass ...... Formation and Lymphomagenesis
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EZH2 and BCL6 Cooperate to Ass ...... Formation and Lymphomagenesis
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type
label
EZH2 and BCL6 Cooperate to Ass ...... Formation and Lymphomagenesis
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EZH2 and BCL6 Cooperate to Ass ...... Formation and Lymphomagenesis
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prefLabel
EZH2 and BCL6 Cooperate to Ass ...... Formation and Lymphomagenesis
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EZH2 and BCL6 Cooperate to Ass ...... Formation and Lymphomagenesis
@en
P2093
P2860
P1433
P1476
EZH2 and BCL6 Cooperate to Ass ...... Formation and Lymphomagenesis
@en
P2093
Ari M. Melnick
Connie M. Corcoran
Jonathan D. Licht
Katerina Hatzi
Mariano G. Cárdenas
María Teresa Calvo Fernández
Matt Teater
Micah D. Gearhart
Michelle Y. Hamline
P2860
P304
P356
10.1016/J.CCELL.2016.07.006
P577
2016-08-08T00:00:00Z