Neuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer disease - Wikidata - awgldk - TriplyDB

Neuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer disease

Neuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer disease

http://www.wikidata.org/entity/Q28775941

about

Sequencing the chimpanzee genome: insights into human evolution and disease A unique biomedical resource at risk Using animal models to determine the significance of complement activation in Alzheimer's disease Primate aging in the mammalian scheme: the puzzle of extreme variation in brain aging Human-specific derived alleles of CD33 and other genes protect against postreproductive cognitive decline Nonhuman primate models of Alzheimer-like cerebral proteopathy Evolution in health and medicine Sackler colloquium: Evolution of the human lifespan and diseases of aging: roles of infection, inflammation, and nutrition The role of positive selection in determining the molecular cause of species differences in disease Analysis of Five Gene Sets in Chimpanzees Suggests Decoupling between the Action of Selection on Protein-Coding and on Noncoding Elements Proposed association between the hexanucleotide repeat of C9orf72 and opposability index of the thumb.The grandmother effect and the uniqueness of the human aging phenotype Age-related decreases in SYN levels associated with increases in MAP-2, apoE, and GFAP levels in the rhesus macaque prefrontal cortex and hippocampus.Cerebral amyloid β(42) deposits and microvascular pathology in ageing baboons.Structural variation in human apolipoprotein E3 and E4: secondary structure, tertiary structure, and size distribution.Detection of gene expression changes at chromosomal rearrangement breakpoints in evolution Animal models in the drug discovery pipeline for Alzheimer's disease Cross-sectional analysis of the association between age and corpus callosum size in chimpanzees (Pan troglodytes).Neuroprotective Activity of Sibjeondaebo-tang on Aβ Peptide-Induced Damages Tau isoform composition influences rate and extent of filament formation The domestic cat as a natural animal model of Alzheimer's disease.The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice Tauopathy with paired helical filaments in an aged chimpanzee Development of amyloid burden in African Green monkeys.Abeta42 neurotoxicity in primary co-cultures: effect of apoE isoform and Abeta conformation.Brain aging in humans, chimpanzees (Pan troglodytes), and rhesus macaques (Macaca mulatta): magnetic resonance imaging studies of macro- and microstructural changes Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor An exon-based comparative variant analysis pipeline to study the scale and role of frameshift and nonsense mutation in the human-chimpanzee divergence.Human neoteny revisited: The case of synaptic plasticity.Recent rodent models for Alzheimer's disease: clinical implications and basic research.Aerobic glycolysis in the primate brain: reconsidering the implications for growth and maintenance.Comparative Pathology of Aging Great Apes: Bonobos, Chimpanzees, Gorillas, and Orangutans.The Alzheimer's Disease-protective CD33 splice variant mediates adaptive loss of function via diversion to an intracellular pool.Non human primate models for Alzheimer's disease-related research and drug discovery.Alzheimer's disease: experimental models and reality.Spontaneous pancreatic islet amyloidosis in 40 baboons.Proteomic comparison of human and great ape blood plasma reveals conserved glycosylation and differences in thyroid hormone metabolism.Immunohistochemical characteristics of the constituents of senile plaques and amyloid angiopathy in aged cynomolgus monkeys.Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer's disease model mice and macaques.Regional DNA methylation differences between humans and chimpanzees are associated with genetic changes, transcriptional divergence and disease genes.

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P2860

Neuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer disease

http://www.wikidata.org/entity/Q28775941

description

1994 nî lūn-bûn

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1994 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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Neuropathology and apolipoprot ...... ications for Alzheimer disease

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Neuropathology and apolipoprot ...... ications for Alzheimer disease

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Neuropathology and apolipoprot ...... ications for Alzheimer disease

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Neuropathology and apolipoprot ...... ications for Alzheimer disease

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Proceedings of the National Academy of Sciences of the United States of America

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Neuropathology and apolipoprot ...... ications for Alzheimer disease

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B T Hyman

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P2860

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

Amyloid plaque core protein in Alzheimer disease and Down syndrome

Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins

Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

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Alzheimer's disease

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