A simple model of backbone flexibility improves modeling of side-chain conformational variability
about
A smoothed backbone-dependent rotamer library for proteins derived from adaptive kernel density estimates and regressionsPrinciples and Overview of Sampling Methods for Modeling Macromolecular Structure and DynamicsA Correspondence Between Solution-State Dynamics of an Individual Protein and the Sequence and Conformational Diversity of its FamilyIncreasing Sequence Diversity with Flexible Backbone Protein Design: The Complete Redesign of a Protein Hydrophobic CoreProtein design: Past, present, and futureQuantifying Correlations Between Allosteric Sites in Thermodynamic EnsemblesProbing the flexibility of large conformational changes in protein structures through local perturbationsFlexible backbone sampling methods to model and design protein alternative conformationsPrediction of mutational tolerance in HIV-1 protease and reverse transcriptase using flexible backbone protein designAssessment of flexible backbone protein design methods for sequence library prediction in the therapeutic antibody Herceptin-HER2 interfacePredicting the tolerated sequences for proteins and protein interfaces using RosettaBackrub flexible backbone designRosettaBackrub--a web server for flexible backbone protein structure modeling and designNovel Ricin Subunit Antigens With Enhanced Capacity to Elicit Toxin-Neutralizing Antibody Responses in Mice.GRID: a high-resolution protein structure refinement algorithm.Rapid flexible docking using a stochastic rotamer library of ligandsThe role of local backrub motions in evolved and designed mutationsAssessing the native state conformational distribution of ubiquitin by peptide acidityRosetta:MSF: a modular framework for multi-state computational protein design.Accessing ns-micros side chain dynamics in ubiquitin with methyl RDCs.Finding Our Way in the Dark Proteome.Computer-aided design of functional protein interactions.Computational design of protein-ligand interfaces: potential in therapeutic development.Multistate approaches in computational protein design.Data driven flexible backbone protein design.Protein backbone ensemble generation explores the local structural space of unseen natural homologs.Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigenConservation of side-chain dynamics within a protein family.Correlation between local structural dynamics of proteins inferred from NMR ensembles and evolutionary dynamics of homologues of known structure.MetREx: a protein design approach for the exploration of sequence-reactivity relationships in metalloenzymes.
P2860
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P2860
A simple model of backbone flexibility improves modeling of side-chain conformational variability
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A simple model of backbone fle ...... ain conformational variability
@ast
A simple model of backbone fle ...... ain conformational variability
@en
type
label
A simple model of backbone fle ...... ain conformational variability
@ast
A simple model of backbone fle ...... ain conformational variability
@en
prefLabel
A simple model of backbone fle ...... ain conformational variability
@ast
A simple model of backbone fle ...... ain conformational variability
@en
P2093
P2860
P3181
P1476
A simple model of backbone fle ...... ain conformational variability
@en
P2093
Anthony J Linares
Colin A Smith
Gregory D Friedland
P2860
P304
P3181
P356
10.1016/J.JMB.2008.05.006
P407
P577
2008-07-18T00:00:00Z