RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer - Wikidata - awgldk - TriplyDB

RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer

RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer

http://www.wikidata.org/entity/Q29012761

about

RhoC regulates the proliferation of gastric cancer cells through interaction with IQGAP1 Rac and Rho GTPases in cancer cell motility control Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival Pyk2 and Src mediate signaling to CCL18-induced breast cancer metastasis The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma Notch1 regulates the functional contribution of RhoC to cervical carcinoma progression Bif-1 promotes tumor cell migration and metastasis via Cdc42 expression and activity.RhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer.Cell aggregation induces phosphorylation of PECAM-1 and Pyk2 and promotes tumor cell anchorage-independent growth.Pyk2 activation triggers epidermal growth factor receptor signaling and cell motility after wounding sheets of epithelial cells.Phosphorylation of focal adhesion kinase at Tyr397 in gastric carcinomas and its clinical significance.Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes.Overexpression of Ras homologous C (RhoC) induces malignant transformation of hepatocytes in vitro and in nude mouse xenografts.HCMV pUS28 initiates pro-migratory signaling via activation of Pyk2 kinase Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness Human beta-defensin-1 suppresses tumor migration and invasion and is an independent predictor for survival of oral squamous cell carcinoma patients Statins and prostate cancer: role of cholesterol inhibition vs. prevention of small GTP-binding proteins RhoC and ROCKs regulate cancer cell interactions with endothelial cells.Oncogenic activation in prostate cancer progression and metastasis: Molecular insights and future challenges.Calcium/calmodulin-dependent protein kinase kinase 2 regulates macrophage-mediated inflammatory responses.miR-509 suppresses brain metastasis of breast cancer cells by modulating RhoC and TNF-α.HOXD10 acts as a tumor-suppressive factor via inhibition of the RHOC/AKT/MAPK pathway in human cholangiocellular carcinoma Blockade of extracellular NM23 or its endothelial target slows breast cancer growth and metastasis.Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome.Roles of rho GTPases in intracellular transport and cellular transformation.Breast cancer metastasis suppressor 1 coordinately regulates metastasis-associated microRNA expression The dual kinase complex FAK-Src as a promising therapeutic target in cancer CaMKK2: a novel target for shaping the androgen-regulated tumor ecosystem.GAP-independent functions of DLC1 in metastasis.Rho GTPases modulate malignant transformation of tumor cells.RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis.RhoC and guanine nucleotide exchange factor Net1 in androgen-unresponsive mouse mammary carcinoma SC-4 cells and human prostate cancer after short-term endocrine therapy.Rho GTPases and cancer.Inhibitory effects of antagonists of growth hormone-releasing hormone on growth and invasiveness of PC3 human prostate cancer.Human bone marrow-derived mesenchymal stem cells produced TGFbeta contributes to progression and metastasis of prostate cancer.The interaction of PKN3 with RhoC promotes malignant growth.Akt and RhoA inhibition promotes anoikis of aggregated B16F10 melanoma cells.Tumor suppressor microRNA-493 decreases cell motility and migration ability in human bladder cancer cells by downregulating RhoC and FZD4.Involvement of the Syk-mTOR pathway in follicular lymphoma cell invasion and angiogenesis.Interleukin-24 inhibits osteosarcoma cell migration and invasion via the JNK/c-Jun signaling pathways.

P2860

Q21090846-258F289B-9F30-49F9-829C-F0017CB0978F Q21245504-793028ED-11AD-423D-8A62-FB533CEBE031 Q24313400-82D3E6F1-B152-4DC7-B0E3-265AA2E12C5E Q28300598-67F77CF6-FE41-4A50-A0AD-6C318A8FF239 Q28477884-CBDE4064-C484-407B-BFF1-360A6432A085 Q29542551-7BD00C32-260A-443D-B217-252BD152848B Q30008851-5C1B5EEB-F261-4EE8-ABBA-C1AFADF3AC12 Q30301104-4DA4334D-1169-4E4A-BDF1-9CCA3F4BE3E8 Q33645244-B26008DA-47C0-4C9A-92E7-3995F75BE581 Q33809899-903B526D-BDF7-4780-A890-CA73CB5A519E Q34162284-BBD30F76-997C-4B67-A4AD-13E111BBE4A8 Q34388520-57C5A026-D3C9-4D94-A2C0-6681958D3E94 Q34575426-98280DB8-C59B-432B-AB2E-CB10266A1F75 Q34631652-49CC4192-C088-41C8-8CBE-9F775E1E7105 Q35022183-8B3A43DB-4161-4D44-9FFA-CA3F3DAAB526 Q35128306-61ACEF29-5186-49FE-9ED1-B03464C3D6B7 Q35264079-76AD6C76-B41F-4FD3-9F41-EC3039F486C5 Q35665403-E9864355-FC7A-4268-A1E8-CE2184F00E53 Q35838821-AFEA6D4B-DB3D-48B7-8188-8EB5F6D6D166 Q35879433-EF8523CD-32E0-4C33-9770-43449A245361 Q35931711-F2910A1E-066A-4BAE-9413-F5F5945264C8 Q36041680-8D0DC46A-DBF2-4159-B238-F8D3F9A69416 Q36086478-57B4576A-117F-4709-9E50-E9C6E5C7D28A Q36236135-E4F9197E-E791-4BA5-A4A1-F475CEDB223D Q36820419-C855DB59-8FDC-41E2-8A13-7E221A3E78FB Q37359847-94364F3A-1D7F-431F-B367-90170EDDBB52 Q37771259-3CE7F37B-B571-4155-A784-D3AA26494D8C Q38075267-F1363481-22CB-40FA-8ABB-922619EC4E70 Q38171331-DDB3A2E7-1694-4C74-8CD5-B1BF1E356F62 Q38230951-53BA50D8-5F46-4C14-B2CA-138792305330 Q38274663-B190D58E-0637-48EF-AE75-73DAC853DE61 Q38330186-4F73BE5D-FF38-4E28-8863-7D529550C4CA Q39283279-20460AAE-AC1E-4482-9242-0174A047279E Q39317388-F51F93CF-2A5F-4139-99B2-ED95FB466913 Q39339902-B4CEB19D-953F-4AE2-ABB9-3C43898B6620 Q39417786-BE7938D2-3CE9-4D65-A005-FD54CF427AFA Q39445926-1ADE0337-266D-4276-A829-C0DC23866233 Q39447197-1E34114A-7A41-4AC1-A0F0-0A2C21DB5DD7 Q39472188-EB9AA45B-491F-4101-AF18-E6D860A78D81 Q41919121-68CE2E37-9A11-4817-B5E1-43237F151303

P2860

RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer

http://www.wikidata.org/entity/Q29012761

description

2008 nî lūn-bûn

@nan

2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer

@ast

RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer

@en

type

label

RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer

@ast

RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer

@en

prefLabel

RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer

@ast

RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer

@en

P1433

Q29012761-0518966C-AAFB-4F3D-A2D0-E197A51DA78C

P1476

Q29012761-2B42438D-8ADD-464B-A82E-EBCA011865FE

P2093

Q29012761-0C69E994-20B3-4C13-82B1-F26E871BD18F

Q29012761-0EA78E6F-37B3-40A2-9289-055E54FF3A79

Q29012761-311EEF30-FD36-4383-8660-057EC319FCB0

Q29012761-38CF8CE0-15B0-4EF0-B1D6-9965E356B3A5

Q29012761-399FFD65-3DA8-49D7-8047-4623FEF1F4B3

Q29012761-48C47D68-7095-4CCE-BED3-3E2DEE9EFBD9

Q29012761-54BBBDEC-6F28-47BC-BFEB-E774FF7A09B5

Q29012761-73DD3C83-DA16-4822-B4AC-518250C8651E

Q29012761-78433140-6066-4362-98B8-A97B1CE04172

Q29012761-830E4AC6-AA72-4A34-BB1F-718969F37A92

P2860

Q29012761-08E1874A-81A5-4C2C-A014-83DFF124E5FC

Q29012761-0C90103C-A7A3-4237-A935-F7A8364DDAE3

Q29012761-1309D119-5A52-4FA2-8A50-08FE55624AC9

Q29012761-22E5BB3D-FB3E-40B0-A056-6F0678353793

Q29012761-308208F2-7359-4835-9A6C-3B5848193752

Q29012761-333FCB5D-877C-4A0A-BACB-8476179AD00B

Q29012761-35793D81-D26A-4193-B48B-54CB852A2EB3

Q29012761-432C998B-0301-48A6-A81D-238AF36EB6C6

Q29012761-44B89C6E-8BB5-4DCF-A441-7CD2E32AA61B

Q29012761-44E95E39-8AD7-4313-AEDA-1CAA5B591A3B

P304

Q29012761-15482D90-0E41-468B-A677-40F9A8975AEC

P31

Q29012761-10DCDB98-2AA1-4037-958B-BB0CD22FBB82

P356

Q29012761-E8D04345-94DD-49C3-AD91-539BDE62BD10

P407

Q29012761-351498C2-571E-44DF-B374-ACA5C35B8AE5

P433

Q29012761-B1E25D7F-B7C8-484B-9BDE-7B9699624761

P478

Q29012761-60533346-5D74-43EB-ACC0-BCB9073191B7

P577

Q29012761-5F233B4F-D6F4-477D-8BA1-2953E8941983

P698

Q29012761-FE60B80C-E60F-40D8-95F1-CBCC67173EA1

P932

Q29012761-2E16C9CF-4ACE-43D2-9FC8-6A81507D2453

P356

0008-5472.CAN-07-6700

P1433

Cancer Research

P1476

RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer

@en

P2093

A. Kobayashi

http://www.w3.org/2001/XMLSchema#string

E. Furuta

http://www.w3.org/2001/XMLSchema#string

F. Xing

http://www.w3.org/2001/XMLSchema#string

H. Okuda

http://www.w3.org/2001/XMLSchema#string

K. Miura

http://www.w3.org/2001/XMLSchema#string

K. Saito

http://www.w3.org/2001/XMLSchema#string

K. Watabe

http://www.w3.org/2001/XMLSchema#string

M. Iiizumi

http://www.w3.org/2001/XMLSchema#string

M. Watabe

http://www.w3.org/2001/XMLSchema#string

S. Bandyopadhyay

http://www.w3.org/2001/XMLSchema#string

P2860

Semaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway

RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis.

ARK5 is a tumor invasion-associated factor downstream of Akt signaling

RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion

FAK integrates growth-factor and integrin signals to promote cell migration

Signaling through focal adhesion kinase

Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer

RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility

Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility

Rho and Rac take center stage

P304

7613-7620

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/0008-5472.CAN-07-6700

http://www.w3.org/2001/XMLSchema#string

P407

P433

18

http://www.w3.org/2001/XMLSchema#string

P478

68

http://www.w3.org/2001/XMLSchema#string

P577

2008-09-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

18794150

http://www.w3.org/2001/XMLSchema#string

P932

2741300

http://www.w3.org/2001/XMLSchema#string