Discodermolide: a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta
about
Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the "Supply Problem"Cancer wars: natural products strike backAxonal Transport and Neurodegeneration: How Marine Drugs Can Be Used for the Development of TherapeuticsDiversity of microbes associated with the marine sponge, Haliclona simulans, isolated from Irish waters and identification of polyketide synthase genes from the sponge metagenome.Biological activities of aqueous and organic extracts from tropical marine sponges.Natural product synthesis at the interface of chemistry and biology.Synthesis of (+)-discodermolide by catalytic stereoselective borylation reactions.Bioactive natural products from Papua New Guinea marine sponges.Natural products from the Lithistida: a review of the literature since 2000.Conformation-activity relationships of polyketide natural products.Utilizing the power of microbial genetics to bridge the gap between the promise and the application of marine natural products.Epothilones: novel microtubule-stabilising agents.Microtubule drugs: action, selectivity, and resistance across the kingdoms of life.The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents: curative effects of desoxyepothilones B and F against human tumor xenografts in nude mice.Anticancer drugs from nature--natural products as a unique source of new microtubule-stabilizing agents.Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products.Metabolites from symbiotic bacteria.Microtubule stabilising agents for cancer chemotherapy.Marine natural products with P-glycoprotein inhibitor properties.Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges.Recent progress with microtubule stabilizers: new compounds, binding modes and cellular activities.Conformational analysis of δ-lactones by DFT calculations: the parent compound and its monomethyl and selected dimethyl derivatives.Developing Streptomyces venezuelae as a cell factory for the production of small molecules used in drug discovery.Structural Basis of Microtubule Stabilization by Discodermolide.Antioxidant, anti-inflammatory, and antiproliferative activities of organic fractions from the Mediterranean brown seaweed Cystoseira sedoides.Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol.Design, synthesis and biological evaluation of a macrocyclic discodermolide/dictyostatin hybrid.Mariculture and natural production of the antitumoural (+)-discodermolide by the Caribbean marine sponge Discodermia dissoluta.A facile synthesis of 5,5-dideutero-4-dimethyl(phenyl)silyl-6-undecyl-tetrahydropyran-2-one as a deuterium labeled synthon for (-)-tetrahydrolipstatin and (+)-δ-hexadecanolide.Quinoline-2-carboimine copper complex immobilized on amine functionalized silica coated magnetite nanoparticles: a novel and magnetically retrievable catalyst for the synthesis of carbamates via C-H activation of formamides.Generation of molecular complexity from cyclooctatetraene using dienyliron and olefin metathesis methodology.The Negishi Cross-Coupling in the Synthesis of Natural Products and Bioactive Molecules
P2860
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P2860
Discodermolide: a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta
description
1990 nî lūn-bûn
@nan
1990 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Discodermolide: a new bioactiv ...... e sponge Discodermia dissoluta
@ast
Discodermolide: a new bioactiv ...... e sponge Discodermia dissoluta
@en
type
label
Discodermolide: a new bioactiv ...... e sponge Discodermia dissoluta
@ast
Discodermolide: a new bioactiv ...... e sponge Discodermia dissoluta
@en
prefLabel
Discodermolide: a new bioactiv ...... e sponge Discodermia dissoluta
@ast
Discodermolide: a new bioactiv ...... e sponge Discodermia dissoluta
@en
P2093
P3181
P356
P1476
Discodermolide: a new bioactiv ...... e sponge Discodermia dissoluta
@en
P2093
Gayle K. Schulte
Malika Gunasekera
Ross E. Longley
Sarath P. Gunasekera
P304
P3181
P356
10.1021/JO00303A029
P407
P577
1990-08-01T00:00:00Z