The Abl family kinases: Mechanisms of regulation and signaling
about
Cytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-beta signaling by sequestration of the Smad proteinsc-Abl tyrosine kinase interacts with MAVS and regulates innate immune responseCharting the molecular network of the drug target Bcr-AblRNAi screen reveals an Abl kinase-dependent host cell pathway involved in Pseudomonas aeruginosa internalizationc-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expressionFluorescence Polarization Screening Assays for Small Molecule Allosteric Modulators of ABL Kinase FunctionAbl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survivalc-Abl tyrosine kinase plays a critical role in β2 integrin-dependent neutrophil migration by regulating Vav1 activity.Enhancement of B-cell receptor signaling by a point mutation of adaptor protein 3BP2 identified in human inherited disease cherubism.Proteins that bind the Src homology 3 domain of CrkI have distinct roles in Crk transformationAbl promotes cadherin-dependent adhesion and signaling in myoblasts.c-Abl regulates estrogen receptor alpha transcription activity through its stabilization by phosphorylation.The NF-kappaB pathway blockade by the IKK inhibitor PS1145 can overcome imatinib resistance.RNA interference screen identifies Abl kinase and PDGFR signaling in Chlamydia trachomatis entry.c-Abl tyrosine kinase regulates cardiac growth and development.c-Abl regulates gastrointestinal muscularis propria homeostasis via ERKsc-Abl activates janus kinase 2 in normal hematopoietic cells.Drosophila Abelson kinase mediates cell invasion and proliferation through two distinct MAPK pathways.Abl kinases are required for invadopodia formation and chemokine-induced invasion.MicroRNA-4723 inhibits prostate cancer growth through inactivation of the Abelson family of nonreceptor protein tyrosine kinases.Differential and opposing effects of imatinib on LPS- and ventilator-induced lung injury.Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies.c-Abl silencing reduced the inhibitory effects of TGF-β1 on apoptosis in systemic sclerosis dermal fibroblasts.c-Abl tyrosine kinase regulates serum-induced nuclear export of diacylglycerol kinase α by phosphorylation at Tyr-218Discovery of Novel Antiangiogenic Marine Natural Product Scaffolds.Abl tyrosine kinases regulate cell-cell adhesion through Rho GTPases.Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis.Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivo.Structure and dynamic regulation of Abl kinases.Aberrant cytokine signaling in leukemia.A role for c-Abl in cell senescence and spontaneous immortalization.Abl kinases regulate autophagy by promoting the trafficking and function of lysosomal componentsActivated c-Abl tyrosine kinase in malignant solid tumors.ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling.N-myristoylated c-Abl tyrosine kinase localizes to the endoplasmic reticulum upon binding to an allosteric inhibitor.DNA damage stress response in germ cells: role of c-Abl and clinical implications.Kinase activation in circulating cells: opportunities for biomarkers for diagnosis and therapeutic monitoring.Non-receptor protein tyrosine kinases signaling pathways in normal and cancer cells.New insights into the interaction of Mycobacterium tuberculosis and human macrophages.New perspectives on the roles of Abl tyrosine kinase in axon patterning.
P2860
Q24316283-59B4109F-9E1F-475F-AC25-7F83066E0883Q24317392-EA075449-9A0F-48D6-8AE7-6FC97EBFEDB8Q24317707-D65A70E2-80FE-44BA-9D11-1AA53DBD3C84Q28472290-80692FDF-D1BF-4CCD-B067-45D0FF15BFE9Q28504995-54F0E03F-FF8F-44F2-A8B8-1BB28E817E29Q28546849-8BA9A8C4-61D5-4B53-966B-93495F00091AQ28586705-926473D8-24B3-45D3-AA4D-E9A63200D114Q30009942-E2B3026F-3F49-4094-96E0-53A47F73AE19Q30010265-A6416C65-B41D-42E9-A48A-92223D0D87A4Q30156056-8337EB6C-DFA2-4440-A411-D38E5C13A74EQ30156102-F3D3D311-3B69-45E0-A639-06833CA8797FQ30156984-DCA46D35-8987-499C-A9F9-997EA95DF6DEQ33226589-7CEBD507-7894-476C-8E3C-5C8E642E88A2Q33325917-3E46AC9F-4B15-4A72-91FC-4C88182685AAQ33667001-4592CAA2-E69B-41FC-98B1-E6CC3A24BA02Q33804078-09D2817F-7D4E-45F6-A780-3C59D7E1FD9CQ33985308-68DCF37B-1281-4627-8B2C-6B179583681CQ34056631-53595815-3B73-4DB3-B72D-B8B61BCFAB86Q34401096-9477DC26-57EC-4D17-9DC2-778E8D03F397Q35040740-226CC1B2-F15B-4283-B257-A7D0CA195770Q35115797-53051CC6-78B5-44E7-9FD7-EE331E5BBE31Q35166848-44B65A10-24C3-4924-8AB5-8BE0E574078DQ35602670-9633D7E7-B8F2-4B6A-B23A-8BEC55865037Q35773985-2E05723C-2A3B-4467-B3E0-02EDADE3496AQ35957698-12902883-AC6E-4C3B-A43F-D64CFA996F78Q36140702-6CFED851-72C5-464A-8F60-2A682C26A9B1Q36229334-E614850C-7FD4-463F-B550-5E501E965B3EQ36322777-55B304C4-286A-4BFD-9624-0A6BADF31DBDQ36635994-03339FE9-9225-4CBC-B2FE-F7ADFD2B7C6EQ36970192-0B3FE3AE-D64A-4237-AF9A-9BCA15E21C8EQ36993393-CF4BAF1C-9391-4EAE-8B2E-6741190CA2A3Q37015051-B8A7460A-B857-4534-A2A4-9370EC935951Q37129818-CCB11928-E00F-4A6E-A651-32C43622FD84Q37189265-A47B7058-238C-46CD-86A3-1707EF1417E2Q37431212-996D5698-FF77-43D4-BC1C-E25186983739Q37785492-06672DD4-FF0E-40EF-802E-A5193F695A61Q38088832-8F757278-0906-4843-8413-62F7458B5A46Q38180461-3049C7E3-6682-452D-B444-36C42D0B1A29Q38206868-9389E023-5C99-40DC-B79A-B67AE3355A3DQ39290721-67D35537-C2A5-46B4-8065-63810223B462
P2860
The Abl family kinases: Mechanisms of regulation and signaling
description
2002 թուականին հրատարակուած գիտական յօդուած
@hyw
2002 թվականին հրատարակված գիտական հոդված
@hy
article
@en
artículu científicu espublizáu en 2002
@ast
wetenschappelijk artikel (gepubliceerd in 2002)
@nl
наукова стаття, опублікована у 2002
@uk
مقالة علمية (نشرت عام 2002)
@ar
ലേഖനം
@ml
name
The Abl family kinases: Mechanisms of regulation and signaling
@ast
The Abl family kinases: Mechanisms of regulation and signaling
@en
type
label
The Abl family kinases: Mechanisms of regulation and signaling
@ast
The Abl family kinases: Mechanisms of regulation and signaling
@en
prefLabel
The Abl family kinases: Mechanisms of regulation and signaling
@ast
The Abl family kinases: Mechanisms of regulation and signaling
@en
P1476
The Abl family kinases: Mechanisms of regulation and signaling
@en
P2093
Ann Marie Pendergast
P304
P356
10.1016/S0065-230X(02)85003-5
P577
2002-01-01T00:00:00Z