Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog
about
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and functionGenome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development.Histogenesis of retinal dysplasia in trisomy 13Characterization of two patched receptors for the vertebrate hedgehog protein familyMutations in NPC1 highlight a conserved NPC1-specific cysteine-rich domainPatched1 interacts with cyclin B1 to regulate cell cycle progressionMediator modulates Gli3-dependent Sonic hedgehog signalingMost germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the PATCHED protein, and no genotype-phenotype correlations are evidentA mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalitiesMice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic developmentDistinct roles of PTCH2 splice variants in Hedgehog signallingOxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cellsEvidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somiteRegulation of patched by sonic hedgehog in the developing neural tubeIndian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formationThe transcription factor paired-related homeobox 1 (Prrx1) inhibits adipogenesis by activating transforming growth factor-β (TGFβ) signalingThe BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanismsTiming neurogenesis and differentiation: insights from quantitative clonal analyses of cerebellar granule cellsEstablishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedbackThe magnitude of hedgehog signaling activity defines skin tumor phenotypeModeling congenital disease and inborn errors of development in Drosophila melanogasterSonic hedgehog signaling in the development of the mouse hypothalamusAberrant activation of the hedgehog signaling pathway in malignant hematological neoplasmsCholesterol metabolism is required for intracellular hedgehog signal transduction in vivoTectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition.Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagusMaking a grade: Sonic Hedgehog signalling and the control of neural cell fateRetinoic acid specifically downregulates Fgf4 and inhibits posterior cell proliferation in the developing mouse autopodTbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1bScube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouseA novel KRAB domain-containing zinc finger transcription factor ZNF431 directly represses Patched1 transcriptionTtc21b is required to restrict sonic hedgehog activity in the developing mouse forebrainHippi is essential for node cilia assembly and Sonic hedgehog signalingFeedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lungThe SIL gene is required for mouse embryonic axial development and left-right specificationHand transcription factors cooperatively regulate development of the distal midline mesenchymePhosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse developmentGcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordiaTemporal deletion of Arl13b reveals that a mispatterned neural tube corrects cell fate over time
P2860
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P2860
Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Conservation of the hedgehog/p ...... mouse patched gene by Hedgehog
@ast
Conservation of the hedgehog/p ...... mouse patched gene by Hedgehog
@en
type
label
Conservation of the hedgehog/p ...... mouse patched gene by Hedgehog
@ast
Conservation of the hedgehog/p ...... mouse patched gene by Hedgehog
@en
prefLabel
Conservation of the hedgehog/p ...... mouse patched gene by Hedgehog
@ast
Conservation of the hedgehog/p ...... mouse patched gene by Hedgehog
@en
P2093
P3181
P356
P1433
P1476
Conservation of the hedgehog/p ...... mouse patched gene by Hedgehog
@en
P2093
Goodrich LV
Johnson RL
McMahon JA
Milenkovic L
P304
P3181
P356
10.1101/GAD.10.3.301
P407
P577
1996-02-01T00:00:00Z