Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies - Wikidata - awgldk - TriplyDB

Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

http://www.wikidata.org/entity/Q29615606

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Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development Passenger deletions generate therapeutic vulnerabilities in cancer Mechanistic evaluation of the novel HSP90 inhibitor NVP-AUY922 in adult and pediatric glioblastoma The PI3K pathway as drug target in human cancer Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma Recent advances in the molecular understanding of glioblastoma Kappa opioids promote the proliferation of astrocytes via Gbetagamma and beta-arrestin 2-dependent MAPK-mediated pathways Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity Comprehensive genomic characterization defines human glioblastoma genes and core pathways Fibroblast growth factor (FGF) and FGF receptor-mediated autocrine signaling in non-small-cell lung cancer cells Genetics and biology of pancreatic ductal adenocarcinoma Glioma Stem Cells: Signaling, Microenvironment, and Therapy Ligand-Independent EGFR Signaling Molecular characterizations of glioblastoma, targeted therapy, and clinical results to date Challenges to targeting epidermal growth factor receptor in glioblastoma: escape mechanisms and combinatorial treatment strategies The dynamic nature of the kinome Glioblastoma cancer stem cells: Biomarker and therapeutic advances Targeted molecular therapies against epidermal growth factor receptor: past experiences and challenges Will kinase inhibitors make it as glioblastoma drugs?Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma Quantitative phenotypic and pathway profiling guides rational drug combination strategies Contemporary murine models in preclinical astrocytoma drug development Role of mesenchymal-epithelial transition amplification in resistance to anti-epidermal growth factor receptor agents CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors Characterizing tyrosine phosphorylation signaling in lung cancer using SH2 profiling Met receptor acts uniquely for survival and morphogenesis of EGFR-dependent normal mammary epithelial and cancer cells Neuroblastoma tyrosine kinase signaling networks involve FYN and LYN in endosomes and lipid rafts Evaluation of tyrosine kinase inhibitor combinations for glioblastoma therapy Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2)SF2312 is a natural phosphonate inhibitor of enolase EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer.Activating mutations in ALK provide a therapeutic target in neuroblastoma.Predictors and Modulators of Synthetic Lethality: An Update on PARP Inhibitors and Personalized Medicine The phosphoinositide 3-kinase pathway and therapy resistance in cancer Current Therapeutic Advances Targeting EGFR and EGFRvIII in Glioblastoma

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Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

http://www.wikidata.org/entity/Q29615606

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2007 nî lūn-bûn

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2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2007 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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Coactivation of receptor tyros ...... or cells to targeted therapies

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Coactivation of receptor tyros ...... or cells to targeted therapies

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Coactivation of receptor tyros ...... or cells to targeted therapies

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Bradner JE

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Brennan C

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Chin L

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DePinho RA

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Nabioullin R

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Stommel JM

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P2860

Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

The phosphoinositide 3-kinase pathway

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

A small molecule-kinase interaction map for clinical kinase inhibitors

ERBB receptors and cancer: the complexity of targeted inhibitors

Malignant glioma: genetics and biology of a grave matter.

The "Gab" in signal transduction.

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287-90

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