Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population - Wikidata - awgldk - TriplyDB

Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

http://www.wikidata.org/entity/Q29616266

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Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak Natural selection fails to optimize mutation rates for long-term adaptation on rugged fitness landscapes Evolution favors protein mutational robustness in sufficiently large populations Insights into arbovirus evolution and adaptation from experimental studies A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replication Silencing of hepatitis A virus infection by small interfering RNAs Viral mutation rates Arbovirus high fidelity variant loses fitness in mosquitoes and mice Viral Polymerase-Helicase Complexes Regulate Replication Fidelity To Overcome Intracellular Nucleotide Depletion Arboviral bottlenecks and challenges to maintaining diversity and fitness during mosquito transmission Genetic Drift, Purifying Selection and Vector Genotype Shape Dengue Virus Intra-host Genetic Diversity in Mosquitoes A full-length infectious cDNA clone of Zika virus from the 2015 epidemic in Brazil as a genetic platform for studies of virus-host interactions and vaccine development Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance Viral quasispecies evolution Genetic Variability of Bovine Viral Diarrhea Virus and Evidence for a Possible Genetic Bottleneck during Vertical Transmission in Persistently Infected Cattle Different domains of the RNA polymerase of infectious bursal disease virus contribute to virulence Structural dynamics as a contributor to error-prone replication by an RNA-dependent RNA polymerase.Group Selection and Contribution of Minority Variants during Virus Adaptation Determines Virus Fitness and Phenotype Spatial pattern switching enables cyclic evolution in spatial epidemics Murine Model for Dengue Virus-Induced Lethal Disease with Increased Vascular Permeability Recent Advances in Deciphering Viral and Host Determinants of Dengue Virus Replication and Pathogenesis The West Nile virus mutant spectrum is host-dependant and a determinant of mortality in mice Genome 3'-end repair in dengue virus type 2 Identification of genetic determinants of a tick-borne flavivirus associated with host-specific adaptation and pathogenicity Growth of an RNA virus in single cells reveals a broad fitness distribution Counteracting Quasispecies Adaptability: Extinction of a Ribavirin-Resistant Virus Mutant by an Alternative Mutagenic Treatment The Marmoset Model of GB Virus B Infections: Adaptation to Host Phenotypic Variation Lack of Adaptation of Chimeric GB Virus B/Hepatitis C Virus in the Marmoset Model: Possible Effects of Bottleneck Experimental Passage of St. Louis Encephalitis Virus In Vivo in Mosquitoes and Chickens Reveals Evolutionarily Significant Virus Characteristics The quasispecies nature and biological implications of the hepatitis C virus Rapid Accumulation of Virulent Rift Valley Fever Virus in Mice from an Attenuated Virus Carrying a Single Nucleotide Substitution in the M RNA Structure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to Ribavirin A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts Mechanisms of viral mutation Mutagenic Effects of Ribavirin on Hepatitis E Virus-Viral Extinction versus Selection of Fitness-Enhancing Mutations Genomic approaches for understanding dengue: insights from the virus, vector, and host Evasion of host immune defenses by human papillomavirus Sequence diversity of dengue virus type 2 in brain and thymus of infected interferon receptor ko mice: implications for dengue virulence

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P2860

Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

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2006年の論文

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Arnold JJ

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Cameron CE

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P2860

RNA virus error catastrophe: direct molecular test by using ribavirin

Efficient Virus Extinction by Combinations of a Mutagen and Antiviral Inhibitors

Mutagenesis versus Inhibition in the Efficiency of Extinction of Foot-and-Mouth Disease Virus

Guanidine-selected mutants of poliovirus: mapping of point mutations to polypeptide 2C

Basic concepts in RNA virus evolution

Rapid evolution of RNA genomes

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

RNA virus mutations and fitness for survival

Viruses at the edge of adaptation.

Poliovirus spreads from muscle to the central nervous system by neural pathways.

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