Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
about
Anaplerotic triheptanoin diet enhances mitochondrial substrate use to remodel the metabolome and improve lifespan, motor function, and sociability in MeCP2-null miceComparative study of methyl-CpG-binding domain proteinsAlterations of GABAergic signaling in autism spectrum disordersThe knockout mouse projectEpigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.The Ski protein family is required for MeCP2-mediated transcriptional repressionThe human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNAInteraction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardationThe methyl-CpG binding protein MBD1 is required for PML-RARalpha function.CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndromeReduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndromeSpecific binding of the methyl binding domain protein 2 at the BRCA1-NBR2 locus.CpG binding protein is crucial for early embryonic developmentExpression of MeCP2 in postmitotic neurons rescues Rett syndrome in micePathophysiology of locus ceruleus neurons in a mouse model of Rett syndromeRett syndrome and MeCP2: linking epigenetics and neuronal functionEmerging pharmacotherapies for neurodevelopmental disordersPathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndromeTranscription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivoSignaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous systemPartial reversal of Rett Syndrome-like symptoms in MeCP2 mutant miceLoss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalitiesThe odyssey of MeCP2 and parental imprintingRett syndrome: clinical review and genetic updateCGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndromeExpression, purification and characterization of methyl DNA binding protein from Bombyx mori.Modifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in DiseaseThe PI3K signaling pathway as a pharmacological target in Autism related disorders and Schizophrenia.Recent advances in understanding synaptic abnormalities in Rett syndromeModeling psychiatric disorders for developing effective treatmentsFunctional alterations of astrocytes in mental disorders: pharmacological significance as a drug targetMECP2 disorders: from the clinic to mice and backInvestigation of Rett syndrome using pluripotent stem cellsThe "quad-partite" synapse: microglia-synapse interactions in the developing and mature CNSAstrocytes conspire with neurons during progression of neurological diseaseThe impact of MeCP2 loss- or gain-of-function on synaptic plasticityThe molecular basis of cognitive deficits in pervasive developmental disordersHow do immune cells support and shape the brain in health, disease, and aging?Abnormalities of the DNA methylation mark and its machinery: an emerging cause of neurologic dysfunction
P2860
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P2860
Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Deficiency of methyl-CpG bindi ...... a Rett-like phenotype in mice
@ast
Deficiency of methyl-CpG bindi ...... a Rett-like phenotype in mice
@en
type
label
Deficiency of methyl-CpG bindi ...... a Rett-like phenotype in mice
@ast
Deficiency of methyl-CpG bindi ...... a Rett-like phenotype in mice
@en
prefLabel
Deficiency of methyl-CpG bindi ...... a Rett-like phenotype in mice
@ast
Deficiency of methyl-CpG bindi ...... a Rett-like phenotype in mice
@en
P2093
P3181
P356
P1433
P1476
Deficiency of methyl-CpG bindi ...... a Rett-like phenotype in mice
@en
P2093
P2888
P304
P3181
P356
10.1038/85906
P407
P577
2001-03-01T00:00:00Z
P5875
P6179
1029028960