Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
about
The use of cystatin C to inhibit epithelial-mesenchymal transition and morphological transformation stimulated by transforming growth factor-beta.The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycleDisabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT)Loss of type III transforming growth factor beta receptor expression increases motility and invasiveness associated with epithelial to mesenchymal transition during pancreatic cancer progressionSumoylated SnoN represses transcription in a promoter-specific mannerThe mechanism of nuclear export of Smad3 involves exportin 4 and RanPin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteinsAP4 encodes a c-MYC-inducible repressor of p21A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stabilityTransforming growth factor-beta1, transforming growth factor-beta2, and transforming growth factor-beta3 enhance ovarian cancer metastatic potential by inducing a Smad3-dependent epithelial-to-mesenchymal transitionIdentification of PCTA, a TGIF antagonist that promotes PML function in TGF-beta signalling15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancersTAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal4E-BP1 is a target of Smad4 essential for TGFbeta-mediated inhibition of cell proliferationSOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignanciesHomeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-β cytostatic program and blocks the antiproliferative effect of TGF-βRequirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells.Breast cancer bone metastasis mediated by the Smad tumor suppressor pathwayIKKalpha, a critical regulator of epidermal differentiation and a suppressor of skin cancerPreclinical efficacy of cystatin C to target the oncogenic activity of transforming growth factor Beta in breast cancerInhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARAAxin and GSK3- control Smad3 protein stability and modulate TGF- signalingNo major association between TGFBR1*6A and prostate cancerSingle small-interfering RNA expression vector for silencing multiple transforming growth factor-beta pathway componentsSignal processing in the TGF-beta superfamily ligand-receptor networkCancer of the Pancreas: Molecular Pathways and Current Advancement in TreatmentMolecular and Cellular Effects of Hydrogen Peroxide on Human Lung Cancer Cells: Potential Therapeutic ImplicationsThe detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinomaStem Cells for Bone Regeneration: From Cell-Based Therapies to Decellularised Engineered Extracellular MatricesClinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathwayGenetic instability in the tumor microenvironment: a new look at an old neighborProlyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteinsTGF-β cascade regulation by PPP1 and its interactors -impact on prostate cancer development and therapyTGF-β and BMP signaling in osteoblast differentiation and bone formationCo-ordination of cell cycle and differentiation in the developing nervous systemTargeting TGF-β signaling in cancerCancer-associated fibroblasts in digestive tumorsA Comprehensive and System Review for the Pharmacological Mechanism of Action of Rhein, an Active Anthraquinone IngredientStructural and biophysical coupling of heparin and activin binding to follistatin isoform functionsStructure ofDrosophilaMad MH2 domain
P2860
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P2860
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
@ast
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
@en
type
label
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
@ast
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
@en
prefLabel
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
@ast
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
@en
P3181
P356
P1476
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
@en
P2093
Peter M Siegel
P2888
P304
P3181
P356
10.1038/NRC1208
P407
P577
2003-11-01T00:00:00Z
P5875
P6179
1004573220