Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
about
RanGTP and CLASP1 cooperate to position the mitotic spindle.Cortical dynein is critical for proper spindle positioning in human cellsOn the Archaeal Origins of Eukaryotes and the Challenges of Inferring Phenotype from GenotypeThe RanGTP Pathway: From Nucleo-Cytoplasmic Transport to Spindle Assembly and BeyondThe Ran Pathway in Drosophila melanogaster MitosisCytoskeletal dynamics: a view from the membraneEpithelial homeostasisOriented divisions, fate decisionsMultisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegansEffect of Cell Shape and Dimensionality on Spindle Orientation and Mitotic TimingInterphase adhesion geometry is transmitted to an internal regulator for spindle orientation via caveolin-1.Direct Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin Clouds.Characterization of ring-like F-actin structure as a mechanical partner for spindle positioning in mitosisF-actin mechanics control spindle centring in the mouse zygote.Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientationSplitting the cell, building the organism: Mechanisms of cell division in metazoan embryosFunctions and mechanics of dynein motor proteinsDNA Damage Response Checkpoint Activation Drives KP1019 Dependent Pre-Anaphase Cell Cycle Delay in S. cerevisiaeCENP-32 is required to maintain centrosomal dominance in bipolar spindle assemblyNuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane.NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein functionCortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphaseThe tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation.Cell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation.Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1.Chromosomal gain promotes formation of a steep RanGTP gradient that drives mitosis in aneuploid cells.An improved optical tweezers assay for measuring the force generation of single kinesin molecules.Dynein light chain 1 and a spindle-associated adaptor promote dynein asymmetry and spindle orientation.MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progressionEvidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cellsThe novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells.Automated tracking of mitotic spindle pole positions shows that LGN is required for spindle rotation but not orientation maintenance.LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex.Direct observation of microtubule pushing by cortical dynein in living cells.Changes in cytoplasmic volume are sufficient to drive spindle scalingExcess centrosomes disrupt endothelial cell migration via centrosome scattering.Force on spindle microtubule minus ends moves chromosomesDlg1 controls planar spindle orientation in the neuroepithelium through direct interaction with LGN.RHAMM deficiency disrupts folliculogenesis resulting in female hypofertility.A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends.
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P248
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P2860
Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Chromosome- and spindle-pole-d ...... indle position and orientation
@ast
Chromosome- and spindle-pole-d ...... indle position and orientation
@en
type
label
Chromosome- and spindle-pole-d ...... indle position and orientation
@ast
Chromosome- and spindle-pole-d ...... indle position and orientation
@en
prefLabel
Chromosome- and spindle-pole-d ...... indle position and orientation
@ast
Chromosome- and spindle-pole-d ...... indle position and orientation
@en
P2860
P921
P3181
P356
P1433
P1476
Chromosome- and spindle-pole-d ...... indle position and orientation
@en
P2093
Tomomi Kiyomitsu
P2860
P2888
P304
P3181
P356
10.1038/NCB2440
P577
2012-02-12T00:00:00Z
P5875
P6179
1015245293