The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*
about
Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1-ARF6 pathwayABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptomsThe human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein familiesGermline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidismProto-oncogene PBF/PTTG1IP regulates thyroid cell growth and represses radioiodide treatmentFunctional expression of the thyrotropin receptor in C cells: new insights into their involvement in the hypothalamic-pituitary-thyroid axisHomeostatic Control of the Thyroid-Pituitary Axis: Perspectives for Diagnosis and TreatmentCurrent loss-of-function mutations in the thyrotropin receptor gene: when to investigate, clinical effects, and treatmentPersistent cAMP-signals triggered by internalized G-protein-coupled receptorsRole for p300 in Pax 8 induction of thyroperoxidase gene expressionMining Chemical Activity Status from High-Throughput Screening AssaysIdentification and structural characterization of the neuronal luteinizing hormone receptor associated with sensory systemsThe impact of long-term exposure to space environment on adult mammalian organisms: a study on mouse thyroid and testisTSH Receptor Signaling Abrogation by a Novel Small MoleculeThe Synergistic Activity of Thyroid Transcription Factor 1 and Pax 8 Relies on the Promoter/Enhancer InterplayStructural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at WorkA tyrosine residue on the TSH receptor stabilizes multimer formationSterol regulatory element-binding proteins are regulators of the NIS gene in thyroid cells.TSH receptor function is required for normal thyroid differentiation in zebrafish.Human TSH receptor ligands as pharmacological probes with potential clinical applicationThe DREAM protein is associated with thyroid enlargement and nodular development.Thyrostimulin, but not thyroid-stimulating hormone (TSH), acts as a paracrine regulator to activate the TSH receptor in mammalian ovaryThyrotropin (TSH) receptor residue E251 in the extracellular leucine-rich repeat domain is critical for linking TSH binding to receptor activationLive imaging of follicle stimulating hormone receptors in gonads and bones using near infrared II fluorophoreNovel insight from transgenic mice into thyroid hormone resistance and the regulation of thyrotropin.Flavonoids, Thyroid Iodide Uptake and Thyroid Cancer-A Review.Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.A small molecule inverse agonist for the human thyroid-stimulating hormone receptorSubclinical thyroid dysfunction and incident hip fracture in older adultsThe endocytic catalysts, Rab5a and Rab7, are tandem regulators of thyroid hormone productionMice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion.The genetics of the thyroid stimulating hormone receptor: history and relevanceThe expression of the thyroid-stimulating hormone (TSH) receptor and the cAMP-dependent protein kinase RII beta regulatory subunit confers TSH-cAMP-dependent growth to mouse fibroblasts.Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice.Influence of the hinge region and its adjacent domains on binding and signaling patterns of the thyrotropin and follitropin receptor.The potential for selective pharmacological therapies through biased receptor signalingAntibody protection reveals extended epitopes on the human TSH receptor.Recent developments in the investigation of thyroid regulation and thyroid carcinogenesisMutations that silence constitutive signaling activity in the allosteric ligand-binding site of the thyrotropin receptor.
P2860
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P2860
The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*
description
1992 nî lūn-bûn
@nan
1992 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*
@ast
The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*
@en
type
label
The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*
@ast
The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*
@en
prefLabel
The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*
@ast
The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*
@en
P3181
P1433
P1476
The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*
@en
P2093
GILBERT VASSART
JACQUES E. DUMONT
P304
P3181
P356
10.1210/EDRV-13-3-596
10.1210/ER.13.3.596
P577
1992-08-01T00:00:00Z