Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite
about
Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteasesMerozoite surface proteins in red blood cell invasion, immunity and vaccines against malariaThe roles of intramembrane proteases in protozoan parasitesParasites, proteomes and systems: has Descartes' clock run out of time?Mechanisms of cellular invasion by intracellular parasitesAntibodies to reticulocyte binding protein-like homologue 4 inhibit invasion of Plasmodium falciparum into human erythrocytesPlasmodium falciparum merozoite invasion is inhibited by antibodies that target the PfRh2a and b binding domainsShedding of TRAP by a rhomboid protease from the malaria sporozoite surface is essential for gliding motility and sporozoite infectivityMaking the cut: central roles of intramembrane proteolysis in pathogenic microorganismsOpen-cap conformation of intramembrane protease GlpGStructural Determination of Functional Units of the Nucleotide Binding Domain (NBD94) of the Reticulocyte Binding Protein Py235 of Plasmodium yoeliiThe structural basis for catalysis and substrate specificity of a rhomboid proteaseBestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidasesActivity-based probes for rhomboid proteases discovered in a mass spectrometry-based assayLarge Lateral Movement of Transmembrane Helix S5 Is Not Required for Substrate Access to the Active Site of Rhomboid Intramembrane ProteaseConformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S′ SubsitesNovel putative glycosylphosphatidylinositol-anchored micronemal antigen of Plasmodium falciparum that binds to erythrocytesBiochemical analysis of the Plasmodium falciparum erythrocyte-binding antigen-175 (EBA175)-glycophorin-A interaction: implications for vaccine designA Presenilin-like protease associated with Plasmodium falciparum micronemes is involved in erythrocyte invasionA Trichomonas vaginalis Rhomboid Protease and Its Substrate Modulate Parasite Attachment and Cytolysis of Host CellsDelineation of stage specific expression of Plasmodium falciparum EBA-175 by biologically functional region II monoclonal antibodiesThe Plasmodium falciparum rhoptry protein RhopH3 plays essential roles in host cell invasion and nutrient uptakePlasmodium falciparum erythrocyte-binding antigen 175 triggers a biophysical change in the red blood cell that facilitates invasionStructures of membrane proteins.Structure and mechanism of rhomboid proteaseFormation of the food vacuole in Plasmodium falciparum: a potential role for the 19 kDa fragment of merozoite surface protein 1 (MSP1(19))In silico identification of specialized secretory-organelle proteins in apicomplexan parasites and in vivo validation in Toxoplasma gondii.Distinct roles of Plasmodium rhomboid 1 in parasite development and malaria pathogenesisMonocyclic β-lactams are selective, mechanism-based inhibitors of rhomboid intramembrane proteasesPlasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole.Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substratesJuxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodiesHow apicomplexan parasites move in and out of cells.Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode.Protease-associated cellular networks in malaria parasite Plasmodium falciparum.Loss-of-function analyses defines vital and redundant functions of the Plasmodium rhomboid protease family.Functional analysis of rhomboid proteases during Toxoplasma invasion.An Entamoeba histolytica rhomboid protease with atypical specificity cleaves a surface lectin involved in phagocytosis and immune evasion.A new class of rhomboid protease inhibitors discovered by activity-based fluorescence polarizationTaking the plunge: integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysis
P2860
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P2860
Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Intramembrane proteolysis medi ...... vasion by the malaria parasite
@ast
Intramembrane proteolysis medi ...... vasion by the malaria parasite
@en
type
label
Intramembrane proteolysis medi ...... vasion by the malaria parasite
@ast
Intramembrane proteolysis medi ...... vasion by the malaria parasite
@en
prefLabel
Intramembrane proteolysis medi ...... vasion by the malaria parasite
@ast
Intramembrane proteolysis medi ...... vasion by the malaria parasite
@en
P2093
P2860
P921
P3181
P356
P1476
Intramembrane proteolysis medi ...... vasion by the malaria parasite
@en
P2093
Chrislaine Withers-Martinez
Fiona Hackett
Michael J Blackman
Nicole Struck
Rebecca A O'Donnell
Steven A Howell
Tim W Gilberger
Zita Krnajski
P2860
P304
P3181
P356
10.1083/JCB.200604136
P407
P577
2006-09-01T00:00:00Z