Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation.
about
Essential role of the coxsackie- and adenovirus receptor (CAR) in development of the lymphatic system in micePodoplanin - a small glycoprotein with many facesA Closer Look at Schlemm's Canal Cell Physiology: Implications for BiomimeticsDevelopment of the mammalian lymphatic vasculaturePlatelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling.Podoplanin: emerging functions in development, the immune system, and cancerThe CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture.CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos.A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy.Platelet ITAM signaling is critical for vascular integrity in inflammation.The N-terminal SH2 domain of Syk is required for (hem)ITAM, but not integrin, signaling in mouse platelets.RASA3 is a critical inhibitor of RAP1-dependent platelet activationRecent advances in the pathobiology and management of Kasabach-Merritt phenomenon.Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond.The role of RNA interference in the developmental separation of blood and lymphatic vasculatureClinicopathological correlations of podoplanin (gp38) expression in rheumatoid synovium and its potential contribution to fibroblast platelet crosstalk.Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregationMutation of threonine 34 in mouse podoplanin-Fc reduces CLEC-2 binding and toxicity in vivo while retaining antilymphangiogenic activity.Integrin-α5β1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation.ProxTom lymphatic vessel reporter mice reveal Prox1 expression in the adrenal medulla, megakaryocytes, and plateletsMucin-type O-glycosylation is critical for vascular integrity.Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and functionBiomaterial guides for lymphatic endothelial cell alignment and migrationConnexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothoraxPlatelets: versatile effector cells in hemostasis, inflammation, and the immune continuumLymphatic vascular morphogenesis in development, physiology, and diseaseAn overview of lymphatic vessels and their emerging role in cardiovascular diseaseEmergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription.Human podoplanin-positive monocytes and platelets enhance lymphangiogenesis through the activation of the podoplanin/CLEC-2 axisThe new era of the lymphatic system: no longer secondary to the blood vascular systemPlatelets regulate lymphatic vascular development through CLEC-2-SLP-76 signalingMyeloid cells and lymphangiogenesis.Role of bone marrow-derived lymphatic endothelial progenitor cells for lymphatic neovascularization.Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation.Molecular regulation of lymphangiogenesis in development and tumor microenvironment.Morphological study of tooth development in podoplanin-deficient mice.Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterningMultiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development.The SYK tyrosine kinase: a crucial player in diverse biological functions.
P2860
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P2860
Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Novel function for blood plate ...... ood and lymphatic circulation.
@ast
Novel function for blood plate ...... ood and lymphatic circulation.
@en
type
label
Novel function for blood plate ...... ood and lymphatic circulation.
@ast
Novel function for blood plate ...... ood and lymphatic circulation.
@en
prefLabel
Novel function for blood plate ...... ood and lymphatic circulation.
@ast
Novel function for blood plate ...... ood and lymphatic circulation.
@en
P2093
P50
P921
P1433
P1476
Novel function for blood plate ...... lood and lymphatic circulation
@en
P2093
Bernd R Binder
Damla Olcaydu
Dontscho Kerjaschki
Elke Fuertbauer
Jan Zaujec
Kari Alitalo
Markus Moser
Paula Haiko
Peter Chrenek
Reinhard Fässler
P304
P356
10.1182/BLOOD-2009-04-216069
P407
P577
2010-01-28T00:00:00Z