Epitope mapping of a bactericidal monoclonal antibody against the factor H binding protein of Neisseria meningitidis.
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Structural and Computational Biology in the Design of Immunogenic Vaccine AntigensRole of factor H binding protein in Neisseria meningitidis virulence and its potential as a vaccine candidate to broadly protect against meningococcal diseaseSolution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen of Neisseria meningitidisStructure of the C-terminal Domain of Neisseria Heparin Binding Antigen (NHBA), One of the Main Antigens of a Novel Vaccine against Neisseria meningitidisDefining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigenMonoclonal antibodies to meningococcal factor H binding protein with overlapping epitopes and discordant functional activityThe modular architecture of meningococcal factor H-binding protein.Impaired immunogenicity of a meningococcal factor H-binding protein vaccine engineered to eliminate factor h binding.A meningococcal factor H binding protein mutant that eliminates factor H binding enhances protective antibody responses to vaccinationMechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodiesComplement-mediated bactericidal activity of anti-factor H binding protein monoclonal antibodies against the meningococcus relies upon blocking factor H binding.A Mutant Library Approach to Identify Improved Meningococcal Factor H Binding Protein Vaccine Antigens.Combined roles of human IgG subclass, alternative complement pathway activation, and epitope density in the bactericidal activity of antibodies to meningococcal factor h binding protein.Molecular Engineering of Ghfp, the Gonococcal Orthologue of Neisseria meningitidis Factor H Binding Protein.Functional Analysis of the Human Antibody Response to Meningococcal Factor H Binding ProteinA broadly cross-reactive monoclonal antibody against an epitope on the n-terminus of meningococcal fHbp.The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: immunological, functional and structural characterization of the antigens.Human IgG1, IgG3, and IgG3 Hinge-Truncated Mutants Show Different Protection Capabilities against Meningococci Depending on the Target Antigen and Epitope Specificity.Discovery of protective B-cell epitopes for development of antimicrobial vaccines and antibody therapeutics.Variation of the factor H-binding protein of Neisseria meningitidisNeisseria meningitidis factor H-binding protein fHbp: a key virulence factor and vaccine antigen.Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp.Human protective response induced by meningococcus B vaccine is mediated by the synergy of multiple bactericidal epitopes.
P2860
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P2860
Epitope mapping of a bactericidal monoclonal antibody against the factor H binding protein of Neisseria meningitidis.
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Epitope mapping of a bacterici ...... ein of Neisseria meningitidis.
@ast
Epitope mapping of a bacterici ...... ein of Neisseria meningitidis.
@en
type
label
Epitope mapping of a bacterici ...... ein of Neisseria meningitidis.
@ast
Epitope mapping of a bacterici ...... ein of Neisseria meningitidis.
@en
prefLabel
Epitope mapping of a bacterici ...... ein of Neisseria meningitidis.
@ast
Epitope mapping of a bacterici ...... ein of Neisseria meningitidis.
@en
P2093
P1476
Epitope mapping of a bacterici ...... tein of Neisseria meningitidis
@en
P2093
Daniele Veggi
Federica Di Marcello
Giacomo Romagnoli
Laura Santini
Lucia Banci
Maria Scarselli
Mariagrazia Pizza
Marzia M Giuliani
Maurizio Comanducci
Rino Rappuoli
P304
P356
10.1016/J.JMB.2008.12.005
P407
P577
2008-12-11T00:00:00Z