NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. - Wikidata - awgldk - TriplyDB

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism.

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism.

http://www.wikidata.org/entity/Q30157499

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Cherubism: best clinical practice Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer HCO3-/Cl- anion exchanger SLC4A2 is required for proper osteoclast differentiation and function Signaling Pathways in Osteoclast Differentiation Regulation of NFATc1 in Osteoclast Differentiation Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1 The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone Tmem178 acts in a novel negative feedback loop targeting NFATc1 to regulate bone mass Transcription factor C/EBPbeta isoform ratio regulates osteoclastogenesis through MafB Inhibitory Effects of KP-A159, a Thiazolopyridine Derivative, on Osteoclast Differentiation, Function, and Inflammatory Bone Loss via Suppression of RANKL-Induced MAP Kinase Signaling Pathway OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo Loss of SH3 domain-binding protein 2 function suppresses bone destruction in tumor necrosis factor-driven and collagen-induced arthritis in mice SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFATc1 and TNF-α-mediated inflammatory bone loss.3BP2 adapter protein is required for receptor activator of NFκB ligand (RANKL)-induced osteoclast differentiation of RAW264.7 cells.Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development Epicardial calcineurin-NFAT signals through Smad2 to direct coronary smooth muscle cell and arterial wall development.Nuclear factor of activated T cells mediates fluid shear stress- and tensile strain-induced Cox2 in human and murine bone cells.Blimp1-mediated repression of negative regulators is required for osteoclast differentiation.Down-regulation of Irf8 by Lyz2-cre/loxP accelerates osteoclast differentiation in vitro.Pro416Arg cherubism mutation in Sh3bp2 knock-in mice affects osteoblasts and alters bone mineral and matrix properties Calcineurin regulates innate antifungal immunity in neutrophils.Osteoclasts: more than 'bone eaters'.Transcriptional regulation of bone and joint remodeling by NFAT SH3BP2 gain-of-function mutation exacerbates inflammation and bone loss in a murine collagen-induced arthritis model Lhx2 regulates bone remodeling in mice by modulating RANKL signaling in osteoclasts.Trophic activity of human P2X7 receptor isoforms A and B in osteosarcoma.Mitf regulates osteoclastogenesis by modulating NFATc1 activity.NFATc1 controls skeletal muscle fiber type and is a negative regulator of MyoD activity.Water extract of the fruits of Alpinia oxyphylla inhibits osteoclast differentiation and bone loss.Connective tissue growth factor (CTGF) transactivates nuclear factor of activated T-cells (NFAT) in cells of the osteoblastic lineage TNF activates calcium-nuclear factor of activated T cells (NFAT)c1 signaling pathways in human macrophages.Reciprocal regulation of Notch and nuclear factor of activated T-cells (NFAT) c1 transactivation in osteoblasts Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation Methanol Extract of Croton Pycnanthus Benth. Inhibits Osteoclast Differentiation by Suppressing the MAPK and NF-κB Signaling Pathways Breast cancer at bone metastatic sites: recent discoveries and treatment targets.Activation of Nfatc2 in osteoblasts causes osteopenia.Osteoimmunology at the nexus of arthritis, osteoporosis, cancer, and infection.Molecular mechanisms of the biphasic effects of interferon-γ on osteoclastogenesis.Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome Stage-specific functions of leukemia/lymphoma-related factor (LRF) in the transcriptional control of osteoclast development.

P2860

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P2860

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism.

http://www.wikidata.org/entity/Q30157499

description

2008 nî lūn-bûn

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2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

NFATc1 in mice represses osteo ...... rom inflammation in cherubism.

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NFATc1 in mice represses osteo ...... rom inflammation in cherubism.

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type

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NFATc1 in mice represses osteo ...... rom inflammation in cherubism.

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NFATc1 in mice represses osteo ...... rom inflammation in cherubism.

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NFATc1 in mice represses osteo ...... rom inflammation in cherubism.

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NFATc1 in mice represses osteo ...... rom inflammation in cherubism.

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Journal of Clinical Investigation

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NFATc1 in mice represses osteo ...... rom inflammation in cherubism.

@en

P2093

Antonios O Aliprantis

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Arnold Park

http://www.w3.org/2001/XMLSchema#string

Bjorn R Olsen

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Kirsten S Sigrist

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Laurie H Glimcher

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Michael C Ostrowski

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Rosalyn Sulyanto

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Sudarshana M Sharma

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Yasuyoshi Ueki

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P2860

Biology of RANK, RANKL, and osteoprotegerin

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

The gene for cherubism maps to chromosome 4p16.

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice

Markers of mouse macrophage development detected by monoclonal antibodies

Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis

RANKL-RANK signaling in osteoclastogenesis and bone disease

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects

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3775-3789

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10.1172/JCI35711

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P433

11

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P478

118

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2008-10-09T00:00:00Z

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23310539

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18846253

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2564610

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