Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation - Wikidata - awgldk - TriplyDB

Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation

Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation

http://www.wikidata.org/entity/Q34599958

about

Epigenetic Regulation of Bone Remodeling and Its Impacts in Osteoporosis Bromodomain and Extra-terminal (BET) Protein Inhibitors Suppress Chondrocyte Differentiation and Restrain Bone Growth.MMP-9 facilitates selective proteolysis of the histone H3 tail at genes necessary for proficient osteoclastogenesis.The role of osteoclast differentiation and function in skeletal homeostasis Osteoclasts-Key Players in Skeletal Health and Disease.Pharmacological targeting of BET proteins inhibits renal fibroblast activation and alleviates renal fibrosis Inhibition of bromodomain and extra-terminal proteins (BET) as a potential therapeutic approach in haematological malignancies: emerging preclinical and clinical evidence.BRD4 localization to lineage-specific enhancers is associated with a distinct transcription factor repertoire.Epigenetic Regulation of Myeloid Cells.Epigenetic regulation of bone cells.Epigenetic drug discovery: breaking through the immune barrier.Immune disease-associated variants in gene enhancers point to BET epigenetic mechanisms for therapeutic intervention.Metabolic-epigenetic coupling in osteoclast differentiation Epigenetic alterations in rheumatoid arthritis fibroblast-like synoviocytes.Review: Enhancers in Autoimmune Arthritis: Implications and Therapeutic Potential.MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERRα Cutting Edge: EZH2 Promotes Osteoclastogenesis by Epigenetic Silencing of the Negative Regulator IRF8.I-BET151 inhibits expression of RANKL, OPG, MMP3 and MMP9 in ankylosing spondylitis in vivo and in vitro.Epigenetics of inflammatory arthritis.In silico design and bioevaluation of selective benzotriazepine BRD4 inhibitors with potent antiosteoclastogenic activity.Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis.The many ways of osteoclast activation.Interplay between genetic and epigenetic mechanisms in rheumatoid arthritis.Enhancer variants reveal a conserved transcription factor network governed by PU.1 during osteoclast differentiation.A Role for MYC in Lithium-Stimulated Repair of the Colonic Epithelium After DSS-Induced Damage in Mice.Bi-directional regulation of cartilage metabolism by inhibiting BET proteins-analysis of the effect of I-BET151 on human chondrocytes and murine joints.

P2860

Q28077554-E2281516-3BC5-49C1-8E14-613AF433050B Q36185007-3C036D04-1527-4C20-A4F4-2CDFC437F302 Q36480906-5A0D040B-9E3C-4BFE-A4E0-61CF414B557D Q36941660-7C3CEFAB-BB40-42D3-8DA4-BBA93406CFAD Q37036135-01718242-5B9E-4ECE-987F-15814FBD42FC Q37688355-DDF93741-C339-406C-8A04-77AA796E6337 Q38542092-A3750A82-7A97-4B91-A906-9BDCDC8B36E0 Q38744593-ACEBF98F-6903-4513-A2F8-A87BF87323CF Q38874524-0CE22CAC-89BB-4272-A3F9-C639F5EB1903 Q38880734-9DF306BA-77EF-46F2-8743-5BB3921C8477 Q38986705-D15954C5-4478-4184-A325-A16ED16E8586 Q39031414-FF6DD76C-3BE5-427C-B54A-898EE7CF59AB Q39089536-E46BC3F2-F44A-4227-939C-E5CE80DF1492 Q39189613-1508D635-055D-4E78-94CD-E5837DEAC874 Q39407376-96795C46-9138-49E3-B475-1E37063AA887 Q41661783-4E8E1F04-6DCF-433C-A3AC-B0838C506C76 Q41858539-269D8912-EDBE-4813-95F8-74436C2F26FE Q42676009-7C170CCA-4606-4DE9-8A58-F0B958FF9F48 Q45967099-B3369CB7-E5A3-4B20-9B42-100B8930CB99 Q48109630-BCE61059-6D71-4E8D-AB38-DD2ED7CFFC40 Q50882156-BCC154A4-E25B-41EF-9CDB-775BA44CBE88 Q50988892-78BDA0B4-7155-46CA-9320-D3743FA60482 Q51092697-1CCF42CB-5DEA-46E6-95AD-1304AC1A7088 Q52331557-C71F1A67-8C49-4406-8877-C7E2106AF95C Q53362870-C6D47070-A82E-49EB-A7B6-5958558EEBD9 Q55287138-161AB06D-07C6-4C20-BFAD-CDDDB63588DD

P2860

Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation

http://www.wikidata.org/entity/Q34599958

description

2014 nî lūn-bûn

@nan

2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Inhibition of osteoclastogenes ...... eins and epigenetic regulation

@ast

Inhibition of osteoclastogenes ...... eins and epigenetic regulation

@en

Inhibition of osteoclastogenes ...... eins and epigenetic regulation

@nl

type

label

Inhibition of osteoclastogenes ...... eins and epigenetic regulation

@ast

Inhibition of osteoclastogenes ...... eins and epigenetic regulation

@en

Inhibition of osteoclastogenes ...... eins and epigenetic regulation

@nl

prefLabel

Inhibition of osteoclastogenes ...... eins and epigenetic regulation

@ast

Inhibition of osteoclastogenes ...... eins and epigenetic regulation

@en

Inhibition of osteoclastogenes ...... eins and epigenetic regulation

@nl

P1433

Q34599958-C1145983-54DA-4F00-AC1D-518B1B33DDD1

P1476

Q34599958-7B634496-8719-4DB8-A3A2-60E68E56401F

P2093

Q34599958-01D12E33-9528-4203-AC1B-ECC9CDE5B01F

Q34599958-024C20C7-D4BA-41F5-9390-2CD4A6D155E2

Q34599958-11BBD588-3A3A-4F9A-A418-A8187AC97711

Q34599958-397316A2-E0F2-4373-919C-7A2A8A62D26F

Q34599958-4D6405E5-CC1D-4C00-8280-A6622EC02499

Q34599958-507793F7-2528-4A17-B0F1-1971E2341CD5

Q34599958-60573DFE-9613-435D-8018-BA2A04C6C472

Q34599958-621EDA72-52DA-42C5-A539-754FCBDDAD22

Q34599958-9257ADC1-7FC8-48BB-AF29-1FF99C62391B

Q34599958-BC7F5874-E553-41AB-9018-DD02B6169345

P2860

Q34599958-17C886B9-977E-4EB9-BBF5-7786F7B4FB7E

Q34599958-18BD52AD-BB1D-45A0-924D-81C5050CE29A

Q34599958-1D72F26F-2D56-4128-82BE-33BE00CA8BB5

Q34599958-1F56116E-E1CF-40C1-B991-06B778D76C2E

Q34599958-26864CD0-17D3-4AC0-8DF2-6A4A58420EA7

Q34599958-286A7799-E670-4457-B98A-B2B3FC927391

Q34599958-2A1C029C-2BA5-44B5-A645-66397E9992B8

Q34599958-2CCEB23D-121E-4017-97BC-F128768DF7C8

Q34599958-33809622-1A44-40F7-80F1-6BA15FC8A81D

Q34599958-34A43D20-F96A-4352-81D1-9F2BE66F7406

P2888

Q34599958-EE8A37B8-3DFB-4444-BE97-F3AF357D04E5

P304

Q34599958-1CBEE2C9-1E01-41D6-9848-1E25CF0B5CEE

P31

Q34599958-43A34898-041C-46B2-AFDB-014256B1A96A

P356

Q34599958-16CFF84F-F2C1-4665-962D-153D452DC1DB

P407

Q34599958-456A535A-D7DB-4E1E-90DE-9E07BD799920

P478

Q34599958-0AFD30B1-2615-4DFA-9E93-4090DBC155C1

P50

Q34599958-2143B2E5-0275-4E5F-A1BF-95DC16E95BFB

Q34599958-E1CE345C-5780-4BBF-BE63-DD8EC724A26F

P577

Q34599958-48084A19-797D-4BD4-AF15-078266AD8FA5

P5875

Q34599958-A77C69F2-88EC-47D6-9404-A997CAB0CBE6

P6179

Q34599958-87C51502-6A77-44D2-8D4E-4C4D4B6370AD

P698

Q34599958-206CB2FB-B9BE-4AC4-B426-9C7C8924468F

P932

Q34599958-7B420A09-BD51-4E04-AADD-F063014F1F49

P356

P1433

Nature Communications

P1476

Inhibition of osteoclastogenes ...... eins and epigenetic regulation

@en

P2093

Anna Yarilina

http://www.w3.org/2001/XMLSchema#string

Baohong Zhao

http://www.w3.org/2001/XMLSchema#string

Elisha Lim

http://www.w3.org/2001/XMLSchema#string

Eugenia Giannopoulou

http://www.w3.org/2001/XMLSchema#string

Jason Witherington

http://www.w3.org/2001/XMLSchema#string

Kevin Lee

http://www.w3.org/2001/XMLSchema#string

Kyung-Hyun Park-Min

http://www.w3.org/2001/XMLSchema#string

Lionel B Ivashkiv

http://www.w3.org/2001/XMLSchema#string

Nicholas Smithers

http://www.w3.org/2001/XMLSchema#string

Paul P Tak

http://www.w3.org/2001/XMLSchema#string

P2860

Selective inhibition of BET bromodomains

Bisphosphonates: mechanism of action and role in clinical practice

Osteoimmunology: interactions of the bone and immune system

Feedback inhibition of osteoclastogenesis during inflammation by IL-10, M-CSF receptor shedding, and induction of IRF8

Suppression of inflammation by a synthetic histone mimic

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

Identification of a novel series of BET family bromodomain inhibitors: binding mode and profile of I-BET151 (GSK1210151A)

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

BET domain co-regulators in obesity, inflammation and cancer

Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems

P2888

P304

5418

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NCOMMS6418

http://www.w3.org/2001/XMLSchema#string

P407

P478

5

http://www.w3.org/2001/XMLSchema#string

P50

Marjolein van der Meulen

P577

2014-11-13T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

268226450

http://www.w3.org/2001/XMLSchema#string

P6179

1048153740

http://www.w3.org/2001/XMLSchema#string

P698

25391636

http://www.w3.org/2001/XMLSchema#string

P932

4249944

http://www.w3.org/2001/XMLSchema#string