Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. - Wikidata - awgldk - TriplyDB

Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization.

Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization.

http://www.wikidata.org/entity/Q30159868

about

PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression Motor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membrane Disruption of PTPRO causes childhood-onset nephrotic syndrome Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible Occurrence of minimal change nephrotic syndrome in classical Hodgkin lymphoma is closely related to the induction of c-mip in Hodgkin-Reed Sternberg cells and podocytes Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1 TRPC6 in glomerular health and disease: what we know and what we believe Podocytes Cell biology and pathology of podocytes Roles of adaptor proteins in podocyte biology The function of endocytosis in podocytes Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis Calcium regulates podocyte actin dynamics.Solution structure analysis of cytoplasmic domain of podocyte protein Neph1 using small/wide angle x-ray scattering (SWAXS)Trans-interaction of nephrin and Neph1/Neph3 induces cell adhesion that associates with decreased tyrosine phosphorylation of nephrin Antiangiogenic treatment diminishes renal injury and dysfunction via regulation of local AKT in early experimental diabetes Protein interactions of the vesicular glutamate transporter VGLUT1 SIRPα interacts with nephrin at the podocyte slit diaphragm CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival Antibodies to protein tyrosine phosphatase receptor type O (PTPro) increase glomerular albumin permeability (P(alb))TM4SF10 and ADAP interaction in podocytes: role in Fyn activity and nephrin phosphorylation Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization Allosteric N-WASP activation by an inter-SH3 domain linker in Nck Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics Direct regulation of nephrin tyrosine phosphorylation by Nck adaptor proteins.Stoichiometry of Nck-dependent actin polymerization in living cells Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation.Nck proteins maintain the adult glomerular filtration barrier.Nck adapter proteins: functional versatility in T cells Podocyte biology and pathogenesis of kidney disease Hemopexin induces nephrin-dependent reorganization of the actin cytoskeleton in podocytes.Sns and Kirre, the Drosophila orthologs of Nephrin and Neph1, direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes.Role of dynamin, synaptojanin, and endophilin in podocyte foot processes.Structural Analysis of the Myo1c and Neph1 Complex Provides Insight into the Intracellular Movement of Neph1 An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms.Inducible nephrin transgene expression in podocytes rescues nephrin-deficient mice from perinatal death Nephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release.Beneficial effects of the Rho kinase inhibitor Y27632 in murine puromycin aminonucleoside nephrosis alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy.Phosphoproteomic analysis reveals regulatory mechanisms at the kidney filtration barrier

P2860

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P2860

Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization.

http://www.wikidata.org/entity/Q30159868

description

2006 nî lūn-bûn

@nan

2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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2006 թվականի մարտին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

@zh-hk

2006年論文

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2006年論文

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2006年论文

@wuu

name

Nephrin ectodomain engagement ...... ent, and actin polymerization.

@ast

Nephrin ectodomain engagement ...... ent, and actin polymerization.

@en

type

label

Nephrin ectodomain engagement ...... ent, and actin polymerization.

@ast

Nephrin ectodomain engagement ...... ent, and actin polymerization.

@en

prefLabel

Nephrin ectodomain engagement ...... ent, and actin polymerization.

@ast

Nephrin ectodomain engagement ...... ent, and actin polymerization.

@en

P1433

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P932

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P356

P1433

Journal of Clinical Investigation

P1476

Nephrin ectodomain engagement ...... ent, and actin polymerization.

@en

P2093

Abdul Soofi

http://www.w3.org/2001/XMLSchema#string

Deepak Nihalani

http://www.w3.org/2001/XMLSchema#string

Iulia Kovari

http://www.w3.org/2001/XMLSchema#string

Kevin Patrie

http://www.w3.org/2001/XMLSchema#string

Lawrence B Holzman

http://www.w3.org/2001/XMLSchema#string

Rakesh Verma

http://www.w3.org/2001/XMLSchema#string

P2860

Modulation of protein translation by Nck-1.

Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation

Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN

Nckbeta adapter regulates actin polymerization in NIH 3T3 fibroblasts in response to platelet-derived growth factor bb

Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin

Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.

Deconstructing the cadherin-catenin-actin complex

Nephrin is specifically located at the slit diaphragm of glomerular podocytes

P304

1346-1359

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scholarly article

P356

10.1172/JCI27414

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P407

P433

5

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P478

116

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2006-03-16T00:00:00Z

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7234813

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P698

16543952

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P921

phosphorylation

P932

1401486

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