An examination of dynamics crosstalk between SH2 and SH3 domains by hydrogen/deuterium exchange and mass spectrometry.
about
Linker length dependent binding of a focal adhesion kinase derived peptide to the Src SH3-SH2 domainsCrystal Structure of the Src Family Kinase Hck SH3-SH2 Linker Regulatory Region Supports an SH3-dominant Activation MechanismDynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its ActivityHydrogen Exchange Mass Spectrometry of Related Proteins with Divergent Sequences: A Comparative Study of HIV-1 Nef Allelic Variants.Dynamics of the Tec-family tyrosine kinase SH3 domains.Subtle Dynamic Changes Accompany Hck Activation by HIV-1 Nef and are Reversed by an Antiretroviral Kinase Inhibitor.Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitmentPartial cooperative unfolding in proteins as observed by hydrogen exchange mass spectrometry.HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, HckTyrosine phosphorylation in the SH3 domain disrupts negative regulatory interactions within the c-Abl kinase core.Abl N-terminal cap stabilization of SH3 domain dynamicsOn the importance of a funneled energy landscape for the assembly and regulation of multidomain Src tyrosine kinases.The Abl SH2-kinase linker naturally adopts a conformation competent for SH3 domain binding.Altered dynamics in Lck SH3 upon binding to the LBD1 domain of Herpesvirus saimiri TipIdentification and characterization of EX1 kinetics in H/D exchange mass spectrometry by peak width analysis.On the solution conformation and dynamics of the HIV-1 viral infectivity factorAllosteric loss-of-function mutations in HIV-1 Nef from a long-term non-progressor.Structure and dynamic regulation of Abl kinases.A mechanism for SRC kinase-dependent signaling by noncatalytic receptors.Localizing the membrane binding region of Group VIA Ca2+-independent phospholipase A2 using peptide amide hydrogen/deuterium exchange mass spectrometryCalcium binding rigidifies the C2 domain and the intradomain interaction of GIVA phospholipase A2 as revealed by hydrogen/deuterium exchange mass spectrometry.Identification of regions of rabbit muscle pyruvate kinase important for allosteric regulation by phenylalanine, detected by H/D exchange mass spectrometry.Functional characterization and conformational analysis of the Herpesvirus saimiri Tip-C484 protein.A selective NMR probe to monitor the conformational transition from inactive to active kinase.
P2860
Q24338375-AD3E09E1-4E87-49FA-83AF-4B3ACC2D2807Q27664248-93EBA475-E371-4087-9B35-EC4661138EDCQ27728152-29C35DA6-DE2A-4DF6-BF65-1E96ABB2A2F7Q30008993-5320D7BF-270C-4C0B-9C52-28960DBD9862Q30009032-17093789-F110-4B39-8B9D-8D9242F2163AQ30009091-0C631D83-B96B-4CD6-9447-66C2136E9269Q30009331-1D9BD430-A7E3-4D39-99F8-AAF1E581C341Q30009855-3D5BE663-5CEF-4898-B0B7-78872930C473Q30010155-9EEB2704-B6A5-4975-99EC-4C58E5DDE3A6Q30157519-50BDD914-36D1-4C7E-A85C-E1772C90F1FBQ30157684-AA288293-89BA-4594-82BF-912E3700D303Q30157892-40CA4838-E9D6-4E2E-A6E9-3260866800BAQ30158039-4556F812-84A3-43E6-9CAF-773BD8252F76Q30159625-DE01F038-EE8D-4BBE-AD4E-CA863B6BABD9Q33252189-43FD633F-ECE7-4992-86D4-5F74CE6169DEQ35113711-5C07E39E-6385-447D-8EF7-C224877BECF6Q36226151-072A66A3-A9B4-4C3F-BE96-6E5A9D276701Q36635994-A53BCF9C-97EC-4558-B063-20FF6EFB52C8Q37150264-F3621EA9-32BA-4A4C-BDAD-B120D07B1EA9Q37358176-97975393-1A29-461E-8C60-D7D220468C3EQ39646620-7E741272-614D-46FF-B6E9-EB78F907B93BQ39726334-790C65CA-C7CA-41FC-BEB5-D7641961C6A6Q41822040-15B61D96-2C8D-422F-AE7E-8B7FBE10A775Q43113518-459C19BB-1D2E-4AA4-ABAC-721B2BC2F7F8
P2860
An examination of dynamics crosstalk between SH2 and SH3 domains by hydrogen/deuterium exchange and mass spectrometry.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
An examination of dynamics cro ...... xchange and mass spectrometry.
@ast
An examination of dynamics cro ...... xchange and mass spectrometry.
@en
type
label
An examination of dynamics cro ...... xchange and mass spectrometry.
@ast
An examination of dynamics cro ...... xchange and mass spectrometry.
@en
prefLabel
An examination of dynamics cro ...... xchange and mass spectrometry.
@ast
An examination of dynamics cro ...... xchange and mass spectrometry.
@en
P2093
P2860
P356
P1433
P1476
An examination of dynamics cro ...... xchange and mass spectrometry.
@en
P2093
Anthony P Schiavone
Edwina C Lerner
James M Hochrein
Thomas E Smithgall
P2860
P356
10.1110/PS.051782206
P577
2005-12-01T00:00:00Z