Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response.
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The major vault protein is a novel substrate for the tyrosine phosphatase SHP-2 and scaffold protein in epidermal growth factor signalingDNA damage-induced G2/M checkpoint in SV40 large T antigen-immortalized embryonic fibroblast cells requires SHP-2 tyrosine phosphataseA Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation.Enhanced cancer stem cell properties of a mitotically quiescent subpopulation of p75NTR-positive cells in esophageal squamous cell carcinoma.Alterations of cell cycle control proteins SHP‑1/2, p16, CDK4 and cyclin D1 in radioresistant nasopharyngeal carcinoma cellsNovel functions of the phosphatase SHP2 in the DNA replication and damage checkpoints.Activating mutations in protein tyrosine phosphatase Ptpn11 (Shp2) enhance reactive oxygen species production that contributes to myeloproliferative disorderProtein Tyrosine Phosphatase SHP-2 (PTPN11) in Hematopoiesis and Leukemogenesis.SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl.SHP-2 tyrosine phosphatase inhibits p73-dependent apoptosis and expression of a subset of p53 target genes induced by EGCG.Mechanisms of PECAM-1-mediated cytoprotection and implications for cancer cell survival.SHP-2 tyrosine phosphatase in human diseases.Dynamic changes in nuclear localization of a DNA-binding protein tyrosine phosphatase TCPTP in response to DNA damage and replication arrest.Inhibition of protein-tyrosine phosphatases by mild oxidative stresses is dependent on S-nitrosylation.Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling.Induction of fibroblast apolipoprotein E expression during apoptosis, starvation-induced growth arrest and mitosis.Phosphatase-dependent and -independent functions of Shp2 in neural crest cells underlie LEOPARD syndrome pathogenesis.Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase.A negative role of SHP-2 tyrosine phosphatase in growth factor-dependent hematopoietic cell survival.SHP-2 phosphatase regulates DNA damage-induced apoptosis and G2/M arrest in catalytically dependent and independent manners, respectively.Molecular functions of SIRPα and its role in cancer.
P2860
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P2860
Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response.
@ast
Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response.
@en
type
label
Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response.
@ast
Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response.
@en
prefLabel
Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response.
@ast
Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response.
@en
P2093
P2860
P356
P1476
Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response.
@en
P2093
Cheng-Kui Qu
Christian C Haudenschild
Liangping Yuan
Wen-Mei Yu
Zhimin Yuan
P2860
P304
15208-15216
P356
10.1074/JBC.M211327200
P407
P577
2003-02-19T00:00:00Z