A motif-based profile scanning approach for genome-wide prediction of signaling pathways.
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The conservation pattern of short linear motifs is highly correlated with the function of interacting protein domainsPhospholipase C delta-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cellsShort Linear Motifs recognized by SH2, SH3 and Ser/Thr Kinase domains are conserved in disordered protein regionsA quantitative protein interaction network for the ErbB receptors using protein microarraysErk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASPA method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domainInteractions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesisPoly-small ubiquitin-like modifier (PolySUMO)-binding proteins identified through a string searchA novel proteomic screen for peptide-protein interactionsA novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKsIdentification and characterization of the interaction between tuberin and 14-3-3zetaThe phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repressionRegulation of TSC2 by 14-3-3 bindingp21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized Rho exchange factorKank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signalingActivity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioningDistinct phosphorylation requirements regulate cortactin activation by TirEPEC and its binding to N-WASPA single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domainsIdentification of a proline-rich Akt substrate as a 14-3-3 binding partnerDomain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation.WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrateProfiling of tyrosine phosphorylation pathways in human cells using mass spectrometry.Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IVTrypanosoma cruzi targets Akt in host cells as an intracellular antiapoptotic strategyProtein kinase Cα phosphorylates a novel argininosuccinate synthase site at serine 328 during calcium-dependent stimulation of endothelial nitric-oxide synthase in vascular endothelial cellsBiography of Lewis C. CantleyPhosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKBAKT/PKB signaling: navigating downstreamScansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifsELM server: A new resource for investigating short functional sites in modular eukaryotic proteinsLIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signalingA genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase CTwo newly characterized germinal center B-cell-associated genes, GCET1 and GCET2, have differential expression in normal and neoplastic B cellsAutomated modelling of signal transduction networks.Phospho.ELM: a database of experimentally verified phosphorylation sites in eukaryotic proteinsSystematic discovery of new recognition peptides mediating protein interaction networksProtein kinases associated with the yeast phosphoproteome.Mapping and analysis of phosphorylation sites: a quick guide for cell biologistsElucidation of the binding preferences of peptide recognition modules: SH3 and PDZ domainsStructural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha
P2860
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P2860
A motif-based profile scanning approach for genome-wide prediction of signaling pathways.
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A motif-based profile scanning approach for genome-wide prediction of signaling pathways.
@ast
A motif-based profile scanning approach for genome-wide prediction of signaling pathways.
@en
type
label
A motif-based profile scanning approach for genome-wide prediction of signaling pathways.
@ast
A motif-based profile scanning approach for genome-wide prediction of signaling pathways.
@en
prefLabel
A motif-based profile scanning approach for genome-wide prediction of signaling pathways.
@ast
A motif-based profile scanning approach for genome-wide prediction of signaling pathways.
@en
P2093
P356
P1433
P1476
A motif-based profile scanning approach for genome-wide prediction of signaling pathways.
@en
P2093
P2888
P304
P356
10.1038/86737
P577
2001-04-01T00:00:00Z