Direct binding of activated c-Src to the beta 3-adrenergic receptor is required for MAP kinase activation.
about
{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligaseBeta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signallingDosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCRTyrosine kinases EnAbling adaptor molecules for chemokine-induced Rap1 activation in T cellsStructural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptorsExpression of beta adrenergic receptors in mouse oocytes and preimplantation embryosSrc-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptorCatechol-O-methyltransferase inhibition increases pain sensitivity through activation of both beta2- and beta3-adrenergic receptorsRegulation of GPCR activity, trafficking and localization by GPCR-interacting proteins.Src homology 3 binding sites in the P2Y2 nucleotide receptor interact with Src and regulate activities of Src, proline-rich tyrosine kinase 2, and growth factor receptors.Molecular conformation dictates signaling module formation: example of PKCepsilon and Src tyrosine kinase.Light-dependent association of Src with photoreceptor rod outer segment membrane proteins in vivo.Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, suppresses hepatic gluconeogenesis through 5'-AMP-activated protein kinase.Maximal beta3-adrenergic regulation of lipolysis involves Src and epidermal growth factor receptor-dependent ERK1/2 activation.Requirement of vimentin filament assembly for beta3-adrenergic receptor activation of ERK MAP kinase and lipolysis.Ligand-directed signalling at beta-adrenoceptorsAgonist-induced internalization and mitogen-activated protein kinase activation of the human prostaglandin EP4 receptor.New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades.Down-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticityArrestin-2 differentially regulates PAR4 and ADP receptor signaling in plateletsDiversity of G protein-coupled receptor signaling pathways to ERK/MAP kinaseStimulation of beta(3)-adrenoceptors causes phosphorylation of p38 mitogen-activated protein kinase via a stimulatory G protein-dependent pathway in 3T3-L1 adipocytes.Mouse beta 3a- and beta 3b-adrenoceptors expressed in Chinese hamster ovary cells display identical pharmacology but utilize distinct signalling pathways.The 'magic tail' of G protein-coupled receptors: an anchorage for functional protein networks.PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome.Obesity and asthma: directions for research.Protein-protein interactions at the adrenergic receptors.5-hydroxytryptamine 4 receptor activation of the extracellular signal-regulated kinase pathway depends on Src activation but not on G protein or beta-arrestin signaling.5-Hydroxytryptamine 5HT2C receptors form a protein complex with N-methyl-D-aspartate GluN2A subunits and activate phosphorylation of Src protein to modulate motoneuronal depolarization.Critical role of Src and SHP-2 in sst2 somatostatin receptor-mediated activation of SHP-1 and inhibition of cell proliferationEP2 Induces p38 Phosphorylation via the Activation of Src in HEK 293 Cells.Crosstalk between BCR/ABL oncoprotein and CXCR4 signaling through a Src family kinase in human leukemia cells.Suppression of hepatic glucose production by human neutrophil alpha-defensins through a signaling pathway distinct from insulin.Signal transduction pathways that contribute to myeloid differentiation.Arrestin-3 is essential for the activation of Fyn by the luteinizing hormone receptor (LHR) in MA-10 cells.Persistent Catechol-O-methyltransferase-dependent Pain Is Initiated by Peripheral β-Adrenergic ReceptorsA novel noncanonical signaling pathway for the μ-opioid receptor.Signaling pathways mediating beta3-adrenergic receptor-induced production of interleukin-6 in adipocytes.β-Adrenoceptor Signaling Networks in Adipocytes for Recruiting Stored Fat and Energy Expenditure.Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.
P2860
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P2860
Direct binding of activated c-Src to the beta 3-adrenergic receptor is required for MAP kinase activation.
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Direct binding of activated c- ...... red for MAP kinase activation.
@ast
Direct binding of activated c- ...... red for MAP kinase activation.
@en
type
label
Direct binding of activated c- ...... red for MAP kinase activation.
@ast
Direct binding of activated c- ...... red for MAP kinase activation.
@en
prefLabel
Direct binding of activated c- ...... red for MAP kinase activation.
@ast
Direct binding of activated c- ...... red for MAP kinase activation.
@en
P2093
P2860
P356
P1476
Direct binding of activated c- ...... red for MAP kinase activation.
@en
P2093
A V Medvedev
K L Pierce
K W Daniel
L M Luttrell
R J Lefkowitz
P2860
P304
38131-38134
P356
10.1074/JBC.C000592200
P407
P577
2000-12-01T00:00:00Z