Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity - Wikidata - awgldk - TriplyDB

Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity

Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity

http://www.wikidata.org/entity/Q30175692

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Amyloid-β Receptors: The Good, the Bad, and the Prion Protein Administration of a selective β2 adrenergic receptor antagonist exacerbates neuropathology and cognitive deficits in a mouse model of Alzheimer's disease The dendritic hypothesis for Alzheimer's disease pathophysiology.Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunities Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers.A long lasting β1 adrenergic receptor stimulation of cAMP/protein kinase A (PKA) signal in cardiac myocytes.Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.Genetic suppression of β2-adrenergic receptors ameliorates tau pathology in a mouse model of tauopathies.Interactions between social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China.Amyloid beta peptide-(1-42) induces internalization and degradation of beta2 adrenergic receptors in prefrontal cortical neurons Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: the case for isradipine.AP-2β regulates amyloid beta-protein stimulation of apolipoprotein E transcription in astrocytes.β2-Adrenergic receptor supports prolonged theta tetanus-induced LTP β2 adrenergic receptor, protein kinase A (PKA) and c-Jun N-terminal kinase (JNK) signaling pathways mediate tau pathology in Alzheimer disease models.APP Receptor? To Be or Not To Be.Adenylyl cyclase anchoring by a kinase anchor protein AKAP5 (AKAP79/150) is important for postsynaptic β-adrenergic signaling.Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the β2-adrenergic receptor in neurons.Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis.Allosteric function and dysfunction of the prion protein.The role of Beta-adrenergic receptor blockers in Alzheimer's disease: potential genetic and cellular signaling mechanisms.Genetically encoded fluorescent biosensors for live-cell visualization of protein phosphorylation.Reflections on glycogen and β-amyloid: why does glycogenolytic β2-adrenoceptor stimulation not rescue memory after β-amyloid?The Binding Receptors of Aβ: an Alternative Therapeutic Target for Alzheimer's Disease.Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus.Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor.Derailed intraneuronal signalling drives pathogenesis in sporadic and familial Alzheimer's disease.β2-adrenergic receptor and astrocyte glucose metabolism.Phosphoinositides: Two-Path Signaling in Neuronal Response to Oligomeric Amyloid β Peptide.The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade.Functionally distinct and selectively phosphorylated GPCR subpopulations co-exist in a single cell.Cellular Receptors of Amyloid β Oligomers (AβOs) in Alzheimer's Disease

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Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity

http://www.wikidata.org/entity/Q30175692

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

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2010年论文

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name

Binding of amyloid beta peptid ...... nt AMPA receptor hyperactivity

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Binding of amyloid beta peptid ...... nt AMPA receptor hyperactivity

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type

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Binding of amyloid beta peptid ...... nt AMPA receptor hyperactivity

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Binding of amyloid beta peptid ...... nt AMPA receptor hyperactivity

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Binding of amyloid beta peptid ...... nt AMPA receptor hyperactivity

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Binding of amyloid beta peptid ...... nt AMPA receptor hyperactivity

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Binding of amyloid beta peptid ...... nt AMPA receptor hyperactivity

@en

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Charles L Cox

http://www.w3.org/2001/XMLSchema#string

Dayong Wang

http://www.w3.org/2001/XMLSchema#string

G Govindaiah

http://www.w3.org/2001/XMLSchema#string

Ruijie Liu

http://www.w3.org/2001/XMLSchema#string

Vania De Arcangelis

http://www.w3.org/2001/XMLSchema#string

Yang K Xiang

http://www.w3.org/2001/XMLSchema#string

P2860

Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule

Protein kinase A regulates AKAP250 (gravin) scaffold binding to the beta2-adrenergic receptor

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex

A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2

Assembly of a beta2-adrenergic receptor--GluR1 signalling complex for localized cAMP signalling

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

A specific amyloid-beta protein assembly in the brain impairs memory

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3511-3521

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scholarly article

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10.1096/FJ.10-156661

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9

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24

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43159977

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20395454

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positive regulation of AMPA receptor activity

Adrenergic receptor, beta 2

Adrenoceptor beta 2

regulation of mini excitatory postsynaptic potential

positive regulation of mini excitatory postsynaptic potential

negative regulation of mini excitatory postsynaptic potential

P932

2923357

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