Mechanism of activation of Pak1 kinase by membrane localization.
about
The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreadingVav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation.Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathwayDok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak.Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylationRegulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1The Bcr kinase downregulates Ras signaling by phosphorylating AF-6 and binding to its PDZ domainDissecting Nck/Dock signaling pathways in Drosophila visual system.Functions and regulation of circular dorsal rufflesPhosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphologyBinding of activated alpha2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMKAltered nitric oxide production mediates matrix-specific PAK2 and NF-κB activation by flowMaturin is a novel protein required for differentiation during primary neurogenesisDissecting activation of the PAK1 kinase at protrusions in living cells.Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B.Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility.BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility.p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway.Bcr is a negative regulator of the Wnt signalling pathwayRepublished: tracing PAKs from GI inflammation to cancerCortactin: a multifunctional regulator of cellular invasivenessEmerging functions of p21-activated kinases in human cancer cells.Inhibition of Cdc42-mediated activation of mixed lineage kinase 3 by the tumor suppressor protein merlin.Kaposi's sarcoma-associated herpesvirus microRNAs repress breakpoint cluster region protein expression, enhance Rac1 activity, and increase in vitro angiogenesis.Regulation of adherens junction dynamics by phosphorylation switches.Structurally unique interaction of RBD-like and PH domains is crucial for yeast pheromone signalingRoles of P21-activated kinases and associated proteins in epithelial wound healing.Tracing PAKs from GI inflammation to cancer.Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase.Rab7 Regulates CDH1 Endocytosis, Circular Dorsal Ruffles Genesis, and Thyroglobulin Internalization in a Thyroid Cell Line.XPak3 promotes cell cycle withdrawal during primary neurogenesis in Xenopus laevis.p21-activated kinases regulate actin remodeling in glomerular podocytes.Human immunodeficiency virus type 1 Nef activates p21-activated kinase via recruitment into lipid raftsLocalization of p21-activated protein kinase gamma-PAK/Pak2 in the endoplasmic reticulum is required for induction of cytostasis.Cell adhesion regulates the interaction between Nck and p21-activated kinase.NCK and PAK participate in the signaling pathway by which vascular endothelial growth factor stimulates the assembly of focal adhesions.Angiotensin II-induced stimulation of p21-activated kinase and c-Jun NH2-terminal kinase is mediated by Rac1 and Nck.Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1.
P2860
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P2860
Mechanism of activation of Pak1 kinase by membrane localization.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mechanism of activation of Pak1 kinase by membrane localization.
@ast
Mechanism of activation of Pak1 kinase by membrane localization.
@en
type
label
Mechanism of activation of Pak1 kinase by membrane localization.
@ast
Mechanism of activation of Pak1 kinase by membrane localization.
@en
prefLabel
Mechanism of activation of Pak1 kinase by membrane localization.
@ast
Mechanism of activation of Pak1 kinase by membrane localization.
@en
P2860
P356
P1433
P1476
Mechanism of activation of Pak1 kinase by membrane localization.
@en
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202361
P407
P577
1999-01-01T00:00:00Z
P5875
P6179
1046357207