Phage display selection of ligand residues important for Src homology 3 domain binding specificity - Wikidata - awgldk - TriplyDB

Phage display selection of ligand residues important for Src homology 3 domain binding specificity

Phage display selection of ligand residues important for Src homology 3 domain binding specificity

http://www.wikidata.org/entity/Q30192920

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ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.The essential role of profilin in the assembly of actin for microspike formation.Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase SET-related cell division autoantigen-1 (CDA1) arrests cell growth Physical and functional interaction of Fyn tyrosine kinase with a brain-enriched Rho GTPase-activating protein TCGAP Src kinase activation by direct interaction with the integrin beta cytoplasmic domain Regulation of FynT function by dual domain docking on PAG/Cbp Novel Src homology 3 domain-binding motifs identified from proteomic screen of a Pro-rich region Ahi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrations A mechanism for combinatorial regulation of electrical activity: Potassium channel subunits capable of functioning as Src homology 3-dependent adaptors Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylation Identification of a new Pyk2 target protein with Arf-GAP activity The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity Computational analysis and prediction of the binding motif and protein interacting partners of the Abl SH3 domain.SH3 domains come of age Crystal Structure of the Src Family Kinase Hck SH3-SH2 Linker Regulatory Region Supports an SH3-dominant Activation Mechanism Directed Evolution Reveals the Binding Motif Preference of the LC8/DYNLL Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands Interaction with the SH3 domain protein Bem1 regulates signaling by the Saccharomyces cerevisiae p21-activated kinase Ste20 Direct interaction between the cytoplasmic tail of ADAM 12 and the Src homology 3 domain of p85alpha activates phosphatidylinositol 3-kinase in C2C12 cells Sequence requirements for association of protein-tyrosine phosphatase PEP with the Src homology 3 domain of inhibitory tyrosine protein kinase p50(csk)Identification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected Src homology 3 domains 'Srcasm: a novel Src activating and signaling molecule Directed discovery of bivalent peptide ligands to an SH3 domain Inhibition of N1-Src kinase by a specific SH3 peptide ligand reveals a role for N1-Src in neurite elongation by L1-CAM.The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease.Directed Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase.The N2-Src neuronal splice variant of C-Src has altered SH3 domain ligand specificity and a higher constitutive activity than N1-Src.The Tyrosine Kinase c-Src Specifically Binds to the Active Integrin αIIbβ3 to Initiate Outside-in Signaling in Platelets A Discovery Strategy for Selective Inhibitors of c-Src in Complex with the Focal Adhesion Kinase SH3/SH2-binding Region.Differential sensitivity of Src-family kinases to activation by SH3 domain displacement.Characterization of domain-peptide interaction interface: prediction of SH3 domain-mediated protein-protein interaction network in yeast by generic structure-based models.Arginine mimetics using α-guanidino acids: introduction of functional groups and stereochemistry adjacent to recognition guanidiniums in peptides Isolation of monobodies that bind specifically to the SH3 domain of the Fyn tyrosine protein kinase.Structure-based characterization of the binding of peptide to the human endophilin-1 Src homology 3 domain using position-dependent noncovalent potential analysis.HIV-1 Tat binds to SH3 domains: cellular and viral outcome of Tat/Grb2 interaction Exploring the activity space of peptides binding to diverse SH3 domains using principal property descriptors derived from amino acid rotamers.Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling.Characterization of domain-peptide interaction interface: a generic structure-based model to decipher the binding specificity of SH3 domains.

P2860

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P2860

Phage display selection of ligand residues important for Src homology 3 domain binding specificity

http://www.wikidata.org/entity/Q30192920

description

1995 nî lūn-bûn

@nan

1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

1995 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

1995年の論文

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1995年学术文章

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1995年学术文章

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1995年学术文章

@zh-hans

1995年学术文章

@zh-my

1995年学术文章

@zh-sg

1995年學術文章

@yue

name

Phage display selection of lig ...... y 3 domain binding specificity

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Phage display selection of lig ...... y 3 domain binding specificity

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type

label

Phage display selection of lig ...... y 3 domain binding specificity

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Phage display selection of lig ...... y 3 domain binding specificity

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prefLabel

Phage display selection of lig ...... y 3 domain binding specificity

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Phage display selection of lig ...... y 3 domain binding specificity

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P1433

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P356

PNAS.92.24.10909

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Phage display selection of lig ...... y 3 domain binding specificity

@en

P2093

J S Brugge

http://www.w3.org/2001/XMLSchema#string

M C Botfield

http://www.w3.org/2001/XMLSchema#string

M J Zoller

http://www.w3.org/2001/XMLSchema#string

P A Henry

http://www.w3.org/2001/XMLSchema#string

R J Rickles

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X M Zhou

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domains

Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions

Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

Protein modules and signalling networks

SH2 domains recognize specific phosphopeptide sequences

Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

Identification of a ten-amino acid proline-rich SH3 binding site

Proline-rich sequences that bind to Src homology 3 domains with individual specificities

Modular binding domains in signal transduction proteins

Structural basis for the binding of proline-rich peptides to SH3 domains

P304

10909-10913

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scholarly article

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10.1073/PNAS.92.24.10909

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P433

24

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P478

92

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1995-11-01T00:00:00Z

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15719009

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7479908

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P932

40540

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