Activating c-kit gene mutations in human germ cell tumors - Wikidata - awgldk - TriplyDB

Activating c-kit gene mutations in human germ cell tumors

Activating c-kit gene mutations in human germ cell tumors

http://www.wikidata.org/entity/Q30304054

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CD117 immunoexpression in canine mast cell tumours: correlations with pathological variables and proliferation markers Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells Somatic DNA mutation analysis in targeted therapy of solid tumours Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential.Identification of kit(M541L) somatic mutation in chronic eosinophilic leukemia, not otherwise specified and its implication in low-dose imatinib response Zebrafish Germ Cell Tumors The complexity of KIT gene mutations and chromosome rearrangements and their clinical correlation in gastrointestinal stromal (pacemaker cell) tumors Hotspot mutations in KIT receptor differentially modulate its allosterically coupled conformational dynamics: impact on activation and drug sensitivity Identification of a novel point mutation of mouse proto-oncogene c-kit through N-ethyl-N-nitrosourea mutagenesis Evaluation of the kinase domain of c-KIT in canine cutaneous mast cell tumors.Epstein-Barr virus associated B-cell lymphoma of brain developing in myelodysplastic syndrome with c-kit mutation (Try-557 -->stop).Recent developments in testicular germ cell tumor research.The clinicopathologic observation, c-KIT gene mutation and clonal status of gastrointestinal stromal tumor in the sacrum Molecular abnormalities in ovarian cancer subtypes other than high-grade serous carcinoma.Dissecting the molecular pathways of (testicular) germ cell tumour pathogenesis; from initiation to treatment-resistance.Correlation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal type Gastrointestinal stromal tumors (GIST): a model for molecule-based diagnosis and treatment of solid tumors.Unphosphorylated STAT5A stabilizes heterochromatin and suppresses tumor growth.Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults.Developmental model for the pathogenesis of testicular carcinoma in situ: genetic and environmental aspects.Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase.Class III receptor tyrosine kinases: role in leukaemogenesis.Management of resectable gastrointestinal stromal tumor.Local signalling environments and human male infertility: what we can learn from mouse models.Gastrointestinal stromal tumors: rationale for surgical adjuvant trials with imatinib.Gastrointestinal stromal tumor - an evolving concept.Kaposi's sarcoma-associated herpesvirus-induced upregulation of the c-kit proto-oncogene, as identified by gene expression profiling, is essential for the transformation of endothelial cells Flumatinib, a selective inhibitor of BCR-ABL/PDGFR/KIT, effectively overcomes drug resistance of certain KIT mutants.Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases.KIT mutations are common in testicular seminomas.Growth regulatory factors and signalling proteins in testicular germ cell tumours.Screening of C-kit gene Mutation in Acute Myeloid Leukaemia in Northern India Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers Biology of gastrointestinal stromal tumors: KIT mutations and beyond.Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors. A study of 200 cases KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors.p85β regulatory subunit of class IA PI3 kinase negatively regulates mast cell growth, maturation, and leukemogenesis.

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P2860

Activating c-kit gene mutations in human germ cell tumors

http://www.wikidata.org/entity/Q30304054

description

1999 nî lūn-bûn

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1999 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հունիսին հրատարակված գիտական հոդված

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1999年の論文

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1999年学术文章

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1999年学术文章

@zh-cn

1999年学术文章

@zh-hans

1999年学术文章

@zh-my

1999年学术文章

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1999年學術文章

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name

Activating c-kit gene mutations in human germ cell tumors

@ast

Activating c-kit gene mutations in human germ cell tumors

@en

type

label

Activating c-kit gene mutations in human germ cell tumors

@ast

Activating c-kit gene mutations in human germ cell tumors

@en

prefLabel

Activating c-kit gene mutations in human germ cell tumors

@ast

Activating c-kit gene mutations in human germ cell tumors

@en

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The American Journal of Pathology

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Activating c-kit gene mutations in human germ cell tumors

@en

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C A Moskaluk

http://www.w3.org/2001/XMLSchema#string

G W Krystal

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H F Frierson

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Q Tian

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P2860

Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors.

Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder.

Microdissection and polymerase chain reaction amplification of genomic DNA from histological tissue sections.

An activating mutation in the kit receptor abolishes the stroma requirement for growth of ELM erythroleukemia cells, but does not prevent their differentiation in response to erythropoietin.

Mechanisms of constitutive activation of c-kit receptor tyrosine kinase.

Autocrine growth of small cell lung cancer mediated by coexpression of c-kit and stem cell factor.

Coexpression of the c-kit and stem cell factor genes in breast carcinomas.

Stem cell factor and c-kit in the mammalian testis: lessons originating from Mother Nature's gene knockouts.

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