Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent.
about
Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway.A novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cellsLipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activityRegulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphateOleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40Molecular cloning and expression regulation of PRG-3, a new member of the plasticity-related gene familySphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosisSelective blockade of lysophosphatidic acid LPA3 receptors reduces murine renal ischemia-reperfusion injury.Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors.Distinct generation, pharmacology, and distribution of sphingosine 1-phosphate and dihydrosphingosine 1-phosphate in human neural progenitor cells.Development of a phosphatase-resistant, L-tyrosine derived LPA1/LPA3 dual antagonist.Cell density-dependent expression of EDG family receptors and mesangial cell proliferation: role in lysophosphatidic acid-mediated cell growth.Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist.Discovery of new G protein-coupled receptors for lipid mediators.Expression of ectolipid phosphate phosphohydrolases in 3T3F442A preadipocytes and adipocytes. Involvement in the control of lysophosphatidic acid production.Lipid phosphate phosphatase-1 expression in cancer cells attenuates tumor growth and metastasis in mice.Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditions.Roles of LPA in ovarian cancer development and progression.Lysophosphatidic acid receptor-3 increases tumorigenicity and aggressiveness of rat hepatoma RH7777 cells.Possible involvement of lysophosphatidic acid receptor-5 gene in the acquisition of growth advantage of rat tumor cells.Lysophospholipid signaling: beyond the EDGs.Lipid phosphate phosphatase-1 regulates lysophosphatidic acid- and platelet-derived-growth-factor-induced cell migration.Regulation of cell survival by lipid phosphate phosphatases involves the modulation of intracellular phosphatidic acid and sphingosine 1-phosphate pools.Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.Enhancement of survival by LPA via Erk1/Erk2 and PI 3-kinase/Akt pathways in a murine hepatocyte cell line.G-protein-coupled receptor stimulation of the p42/p44 mitogen-activated protein kinase pathway is attenuated by lipid phosphate phosphatases 1, 1a, and 2 in human embryonic kidney 293 cells.A lysophosphatidic acid analogue is revealed as a potent inhibitor of phosphatidylcholine synthesis, inducing apoptosis.Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor.Lipid phosphate phosphatases: more than one way to put the brakes on LPA signaling?Serum lysophosphatidic acid is produced through diverse phospholipase pathways.Injury-elicited differential transcriptional regulation of phospholipid growth factor receptors in the cornea.Lysophosphatidic acid promotes the proliferation of adult Schwann cells isolated from axotomized sciatic nerve.
P2860
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P2860
Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent.
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Lysophosphatidic acid-induced ...... d is Edg-receptor independent.
@ast
Lysophosphatidic acid-induced ...... d is Edg-receptor independent.
@en
type
label
Lysophosphatidic acid-induced ...... d is Edg-receptor independent.
@ast
Lysophosphatidic acid-induced ...... d is Edg-receptor independent.
@en
prefLabel
Lysophosphatidic acid-induced ...... d is Edg-receptor independent.
@ast
Lysophosphatidic acid-induced ...... d is Edg-receptor independent.
@en
P2093
P356
P1476
Lysophosphatidic acid-induced ...... nd is Edg-receptor independent
@en
P2093
P304
P356
10.1074/JBC.M007782200
P407
P577
2000-10-19T00:00:00Z