Intracellular signals that control cell proliferation in mammalian balance epithelia: key roles for phosphatidylinositol-3 kinase, mammalian target of rapamycin, and S6 kinases in preference to calcium, protein kinase C, and mitogen-activated protei

Intracellular signals that control cell proliferation in mammalian balance epithelia: key roles for phosphatidylinositol-3 kinase, mammalian target of rapamycin, and S6 kinases in preference to calcium, protein kinase C, and mitogen-activated protei

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http://www.wikidata.org/entity/Q30306742

Q30306742

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A historical to present-day account of efforts to answer the question: "what puts the brakes on mammalian hair cell regeneration?"Over half the hair cells in the mouse utricle first appear after birth, with significant numbers originating from early postnatal mitotic production in peripheral and striolar growth zones In vivo proliferative regeneration of balance hair cells in newborn mice.The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs Variations in shape-sensitive restriction points mirror differences in the regeneration capacities of avian and mammalian ears.Reinforcement of cell junctions correlates with the absence of hair cell regeneration in mammals and its occurrence in birds.Recent advances in hair cell regeneration research.Inner ear hair cells produced in vitro by a mesenchymal-to-epithelial transition The challenge of hair cell regeneration.EGFR signaling is required for regenerative proliferation in the cochlea: conservation in birds and mammals Concise review: Inner ear stem cells--an oxymoron, but why?Identification of modulators of hair cell regeneration in the zebrafish lateral line.ErbB expression: the mouse inner ear and maturation of the mitogenic response to heregulin.CD44 is a marker for the outer pillar cells in the early postnatal mouse inner ear.cAMP-induced auditory supporting cell proliferation is mediated by ERK MAPK signaling pathway.A disorganized innervation of the inner ear persists in the absence of ErbB2.Cellular targets of estrogen signaling in regeneration of inner ear sensory epithelia.Restrictions in cell cycle progression of adult vestibular supporting cells in response to ectopic cyclin D1 expression.The genetics of Ménière's disease.Inhibition of mTOR by Rapamycin Results in Auditory Hair Cell Damage and Decreased Spiral Ganglion Neuron Outgrowth and Neurite Formation In Vitro.A PI3K pathway mediates hair cell survival and opposes gentamicin toxicity in neonatal rat organ of Corti.Histopathology of Meniere's disease.

P2860

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P2860

Intracellular signals that control cell proliferation in mammalian balance epithelia: key roles for phosphatidylinositol-3 kinase, mammalian target of rapamycin, and S6 kinases in preference to calcium, protein kinase C, and mitogen-activated protei

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http://www.wikidata.org/entity/Q30306742

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2001 nî lūn-bûn

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2001 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2001 թվականի հունվարին հրատարակված գիտական հոդված

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2001年の論文

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年學術文章

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